{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Spine+Condition",
    "query": {
      "condition": "Spine Condition"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 502,
    "total_pages": 51,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Spine+Condition&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-21T21:32:16.174Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05534321",
      "title": "Prophylactic Radiotherapy of MInimally Symptomatic Spinal Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Spine Metastases"
      ],
      "interventions": [
        {
          "name": "Prophylactic Radiotherapy",
          "type": "RADIATION"
        },
        {
          "name": "Standard of care systemic therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "Baptist Health South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2022-08-29",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05534321"
    },
    {
      "nct_id": "NCT04421209",
      "title": "Analgesic Effects of Perioperative Propranolol Administration for Spine Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lumbar Disc Disease",
        "Spinal Fusion",
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "Propranolol Hcl 40mg Tab",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-12",
      "completion_date": "2021-09-30",
      "has_results": false,
      "last_update_posted_date": "2021-03-16",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04421209"
    },
    {
      "nct_id": "NCT02802033",
      "title": "A Multicenter Prospective Registry for the Management of Degenerative Spine Disorders",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Diseases, Spinal Cord"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "AO Innovation Translation Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 908,
      "start_date": "2016-01",
      "completion_date": "2025-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 5,
      "location_summary": "Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02802033"
    },
    {
      "nct_id": "NCT07325578",
      "title": "U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Tumor",
        "Osteoporosis",
        "Traumatic Fracture"
      ],
      "interventions": [
        {
          "name": "Percutaneous procedure in the MSK structures of the pelvis and/or the spine",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Precision IO Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-04-28",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 3,
      "location_summary": "San Diego, California • Miami, Florida • Chicago, Illinois",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07325578"
    },
    {
      "nct_id": "NCT05110833",
      "title": "Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine Surgery",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intervertebral Disc Degeneration",
        "Intervertebral Disc Displacement",
        "Spinal Curvatures",
        "Spinal Stenosis",
        "Spondylitis",
        "Spondylosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Allina Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2020-05-01",
      "completion_date": "2026-04",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05110833"
    },
    {
      "nct_id": "NCT04420143",
      "title": "MLX/XLX ACR Expandable Lumbar Interbody Implants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Disc Disease",
        "Spondylolisthesis",
        "Degenerative Scoliosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NuVasive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 109,
      "start_date": "2020-01-27",
      "completion_date": "2020-10-23",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 4,
      "location_summary": "Orange, California • Jacksonville, Florida • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04420143"
    },
    {
      "nct_id": "NCT01292252",
      "title": "Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lumbar Spondylosis",
        "Lumbar Spondylolisthesis",
        "Adult Degenerative Lumbar Scoliosis"
      ],
      "interventions": [
        {
          "name": "teriparatide",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Shane Burch",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "60 Years to 90 Years"
      },
      "enrollment_count": 36,
      "start_date": "2011-08",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2021-05-03",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01292252"
    },
    {
      "nct_id": "NCT06143228",
      "title": "Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Whiplash Injury of Cervical Spine",
        "Muscle Weakness"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "D'Youville College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "19 Years to 70 Years"
      },
      "enrollment_count": 65,
      "start_date": "2023-12-30",
      "completion_date": "2024-12-30",
      "has_results": false,
      "last_update_posted_date": "2024-02-22",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 2,
      "location_summary": "Tallahassee, Florida • Tampa, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06143228"
    },
    {
      "nct_id": "NCT06439953",
      "title": "Irrisept Solution for Instrumented Spine Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Op Complication",
        "Spine Surgery",
        "Site Infection",
        "Surgical Site Infection",
        "Spinal Instrumentation",
        "Index Spinal Instrumentation",
        "Layer-by-Layer Closure",
        "Locoregional Flap-Based Closure"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate solution",
          "type": "DEVICE"
        },
        {
          "name": "Vancomycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Rhode Island Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2024-10-01",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-11-20",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06439953"
    },
    {
      "nct_id": "NCT04792983",
      "title": "Cognition and the Immunology of Postoperative Outcomes",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Impairment",
        "Frail Elderly Syndrome",
        "Delirium",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "No intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2019-09-06",
      "completion_date": "2025-07-31",
      "has_results": false,
      "last_update_posted_date": "2021-03-12",
      "last_synced_at": "2026-07-21T21:32:16.174Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04792983"
    }
  ]
}