{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Stage+1+Hypertension&page=2",
    "query": {
      "condition": "Stage 1 Hypertension",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Stage+1+Hypertension&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T08:30:09.314Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00624065",
      "title": "Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "carvedilol controlled release/lisinopril",
          "type": "DRUG"
        },
        {
          "name": "lisinopril + placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 348,
      "start_date": "2008-03",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2016-12-28",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 76,
      "location_summary": "Mobile, Alabama • Chandler, Arizona • Glendale, Arizona + 66 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Goodyear",
          "state": "Arizona"
        },
        {
          "city": "Litchifield Park/Arizona",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00624065"
    },
    {
      "nct_id": "NCT04761705",
      "title": "Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Ocular Hypertension",
        "Open Angle Glaucoma"
      ],
      "interventions": [
        {
          "name": "JV-GL1",
          "type": "DRUG"
        },
        {
          "name": "Latanoprost 0.005% Ophthalmic Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "JeniVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2021-03-10",
      "completion_date": "2025-07",
      "has_results": false,
      "last_update_posted_date": "2024-05-10",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 1,
      "location_summary": "Newport Beach, California",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04761705"
    },
    {
      "nct_id": "NCT03399604",
      "title": "Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Primary Pulmonary Hypertension"
      ],
      "interventions": [
        {
          "name": "LIQ861 Inhaled Treprostinil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Liquidia Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 121,
      "start_date": "2018-01-02",
      "completion_date": "2019-11-25",
      "has_results": true,
      "last_update_posted_date": "2024-07-30",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 38,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Sacramento, California + 30 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03399604"
    },
    {
      "nct_id": "NCT07223528",
      "title": "TEPH: Telaglenastat Efficacy in Pulmonary Hypertension",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Pulmonary Hypertension"
      ],
      "interventions": [
        {
          "name": "Telaglenastat",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chan, Stephen, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 28,
      "start_date": "2026-08",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223528"
    },
    {
      "nct_id": "NCT03904693",
      "title": "Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)"
      ],
      "interventions": [
        {
          "name": "FDC macitentan/tadalafil",
          "type": "DRUG"
        },
        {
          "name": "Macitentan 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Tadalafil 40 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo FDC",
          "type": "DRUG"
        },
        {
          "name": "Placebo macitentan",
          "type": "DRUG"
        },
        {
          "name": "Placebo tadalafil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Actelion",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 187,
      "start_date": "2019-07-29",
      "completion_date": "2024-09-27",
      "has_results": true,
      "last_update_posted_date": "2025-12-19",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 26,
      "location_summary": "Fullerton, California • Los Angeles, California • Atlanta, Georgia + 22 more",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        },
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03904693"
    },
    {
      "nct_id": "NCT05889650",
      "title": "External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Traumatic Brain Injury",
        "Intracranial Hypertension"
      ],
      "interventions": [
        {
          "name": "External Lumbar drainage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brain Trauma Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-06-24",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 6,
      "location_summary": "Gainesville, Florida • Kansas City, Kansas • Dallas, Texas + 3 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05889650"
    },
    {
      "nct_id": "NCT01463085",
      "title": "Clinical Trial to Assess the Effects of Low-fat Dairy on Systolic Blood Pressure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Low-fat dairy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dairy Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "20 Years to 69 Years"
      },
      "enrollment_count": 65,
      "start_date": "2011-08",
      "completion_date": "2012-08",
      "has_results": false,
      "last_update_posted_date": "2012-05-24",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 1,
      "location_summary": "Glen Ellyn, Illinois",
      "locations": [
        {
          "city": "Glen Ellyn",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01463085"
    },
    {
      "nct_id": "NCT01157364",
      "title": "Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Open-Angle Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "bimatoprost 20 µg generation 2",
          "type": "DRUG"
        },
        {
          "name": "bimatoprost 15 µg generation 2",
          "type": "DRUG"
        },
        {
          "name": "bimatoprost 10 µg generation 2",
          "type": "DRUG"
        },
        {
          "name": "bimatoprost 6 µg generation 2",
          "type": "DRUG"
        },
        {
          "name": "bimatoprost 15 µg generation 1",
          "type": "DRUG"
        },
        {
          "name": "bimatoprost 10 µg generation 1",
          "type": "DRUG"
        },
        {
          "name": "bimatoprost 0.03%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 109,
      "start_date": "2010-09-23",
      "completion_date": "2016-08-09",
      "has_results": true,
      "last_update_posted_date": "2020-03-30",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 36,
      "location_summary": "Artesia, California • La Jolla, California • Los Angeles, California + 31 more",
      "locations": [
        {
          "city": "Artesia",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Rancho Cordova",
          "state": "California"
        },
        {
          "city": "Redding",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01157364"
    },
    {
      "nct_id": "NCT02822222",
      "title": "Safety Study of RMJH-111b to Treat Essential Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Essential Hypertension"
      ],
      "interventions": [
        {
          "name": "Magnesium citrate, tribasic anhydrous soft gelatin capsule",
          "type": "DRUG"
        },
        {
          "name": "Placebo soft gelatin capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "RMJ Holdings, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 22,
      "start_date": "2016-06-10",
      "completion_date": "2016-07-07",
      "has_results": true,
      "last_update_posted_date": "2020-09-23",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 1,
      "location_summary": "Tustin, California",
      "locations": [
        {
          "city": "Tustin",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02822222"
    },
    {
      "nct_id": "NCT01520116",
      "title": "Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hypertension",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Primary Open Angle Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Stage 1 - ATS907 - Dose 1",
          "type": "DRUG"
        },
        {
          "name": "Stage 1 - ATS907 - Dose 2",
          "type": "DRUG"
        },
        {
          "name": "Stage 1 - ATS907 - Dose 3",
          "type": "DRUG"
        },
        {
          "name": "Stage 1 - ATS907 - Dose 4",
          "type": "DRUG"
        },
        {
          "name": "Stage 1 - Vehicle",
          "type": "DRUG"
        },
        {
          "name": "Stage 2 - ATS907 - Dose A - to be selected based on Stage 1",
          "type": "DRUG"
        },
        {
          "name": "Stage 2 - ATS907 - Dose B - to be selected based on Stage 1",
          "type": "DRUG"
        },
        {
          "name": "Timoptic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Altheos, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2012-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2012-11-01",
      "last_synced_at": "2026-07-24T08:30:09.314Z",
      "location_count": 5,
      "location_summary": "Artesia, California • Glendale, California • Saint Joseph, Michigan + 2 more",
      "locations": [
        {
          "city": "Artesia",
          "state": "California"
        },
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "Saint Joseph",
          "state": "Michigan"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01520116"
    }
  ]
}