{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Stage-1+Hypertension", "query": { "condition": "Stage-1 Hypertension" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 35, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Stage-1+Hypertension&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-23T22:24:06.605Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04402385", "title": "Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pre-Eclampsia", "Stage 1 Hypertension", "Elevated Blood Pressure" ], "interventions": [ { "name": "Aspirin 81 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 50, "start_date": "2020-08-06", "completion_date": "2022-06-22", "has_results": true, "last_update_posted_date": "2023-07-11", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT04402385" }, { "nct_id": "NCT01508026", "title": "Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Stage 1 Hypertension", "Stage 2 Hypertension" ], "interventions": [ { "name": "Nebivolol and Valsartan 1", "type": "DRUG" }, { "name": "Nebivolol and Valsartan 2", "type": "DRUG" }, { "name": "Nebivolol and Valsartan 3", "type": "DRUG" }, { "name": "Nebivolol 1", "type": "DRUG" }, { "name": "Nebivolol 2", "type": "DRUG" }, { "name": "Valsartan 1", "type": "DRUG" }, { "name": "Valsartan 2", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4161, "start_date": "2012-01", "completion_date": "2013-05", "has_results": false, "last_update_posted_date": "2014-04-25", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 413, "location_summary": "Birmingham, Alabama • Foley, Alabama • Gulf Shores, Alabama + 290 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01508026" }, { "nct_id": "NCT00422461", "title": "A Dose Finding Study Of PF-00489791 In Patients With Mild To Moderate High Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "placebo", "type": "DRUG" }, { "name": "PF-00489791", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 135, "start_date": "2007-02-27", "completion_date": "2008-01-28", "has_results": true, "last_update_posted_date": "2021-10-11", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 20, "location_summary": "Los Angeles, California • Santa Ana, California • Tustin, California + 15 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Santa Ana", "state": "California" }, { "city": "Tustin", "state": "California" }, { "city": "Farmington", "state": "Connecticut" }, { "city": "Waterbury", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00422461" }, { "nct_id": "NCT06834204", "title": "Advancing Care Coordination Between Cancer and Primary Care Teams for Complex Cancer Survivors", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cancer", "Breast Cancer Early Stage Breast Cancer (Stage 1-3)", "Bladder Cancer", "Prostate Cancer (Adenocarcinoma)", "Endometrial Cancer", "Hypertension", "Hyperlipidemia (E.G., Hypercholesterolemia)", "Diabetes Mellitus" ], "interventions": [ { "name": "PC2: Primary Care Connect", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 266, "start_date": "2026-04-24", "completion_date": "2029-04-30", "has_results": false, "last_update_posted_date": "2026-07-10", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 1, "location_summary": "New Brunswick, New Jersey", "locations": [ { "city": "New Brunswick", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT06834204" }, { "nct_id": "NCT00624065", "title": "Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "carvedilol controlled release/lisinopril", "type": "DRUG" }, { "name": "lisinopril + placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 348, "start_date": "2008-03", "completion_date": "2008-08", "has_results": true, "last_update_posted_date": "2016-12-28", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 76, "location_summary": "Mobile, Alabama • Chandler, Arizona • Glendale, Arizona + 66 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Goodyear", "state": "Arizona" }, { "city": "Litchifield Park/Arizona", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00624065" }, { "nct_id": "NCT01463085", "title": "Clinical Trial to Assess the Effects of Low-fat Dairy on Systolic Blood Pressure", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Low-fat dairy", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Dairy Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "69 Years", "sex": "ALL", "summary": "20 Years to 69 Years" }, "enrollment_count": 65, "start_date": "2011-08", "completion_date": "2012-08", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 1, "location_summary": "Glen Ellyn, Illinois", "locations": [ { "city": "Glen Ellyn", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01463085" }, { "nct_id": "NCT01157364", "title": "Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "bimatoprost 20 µg generation 2", "type": "DRUG" }, { "name": "bimatoprost 15 µg generation 2", "type": "DRUG" }, { "name": "bimatoprost 10 µg generation 2", "type": "DRUG" }, { "name": "bimatoprost 6 µg generation 2", "type": "DRUG" }, { "name": "bimatoprost 15 µg generation 1", "type": "DRUG" }, { "name": "bimatoprost 10 µg generation 1", "type": "DRUG" }, { "name": "bimatoprost 0.03%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 109, "start_date": "2010-09-23", "completion_date": "2016-08-09", "has_results": true, "last_update_posted_date": "2020-03-30", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 36, "location_summary": "Artesia, California • La Jolla, California • Los Angeles, California + 31 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Rancho Cordova", "state": "California" }, { "city": "Redding", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01157364" }, { "nct_id": "NCT01020435", "title": "Chiropractic for Hypertension in Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Spinal Manipulation", "type": "OTHER" }, { "name": "Sham Spinal Manipulation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Palmer College of Chiropractic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "21 Years to 75 Years" }, "enrollment_count": 51, "start_date": "2010-10", "completion_date": "2012-05", "has_results": true, "last_update_posted_date": "2018-02-07", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 1, "location_summary": "Davenport, Iowa", "locations": [ { "city": "Davenport", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT01020435" }, { "nct_id": "NCT00240448", "title": "A Randomized, Double-blind, Placebo Controlled Comparison of Telmisartan Hydrochlorothiazide (HCT) and Valsartan HCT in Hypertension (HTN) Stage I/II Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "telmisartan 80 mg/hydrochlorothiazide 25 mg", "type": "DRUG" }, { "name": "valsartan 160 mg/hydrochlorothiazide 25 mg", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1109, "start_date": "2003-09", "completion_date": null, "has_results": false, "last_update_posted_date": "2013-11-05", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 100, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 90 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Sctoosdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00240448" }, { "nct_id": "NCT00302809", "title": "Blood Pressure Lowering Effects of Grape Juice", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Concord Grape Juice", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Boston University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "21 Years to 75 Years" }, "enrollment_count": 60, "start_date": "2006-03", "completion_date": "2009-05", "has_results": false, "last_update_posted_date": "2009-06-18", "last_synced_at": "2026-07-23T22:24:06.605Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00302809" } ] }