{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Structural+Cardiac+Defects",
    "query": {
      "condition": "Structural Cardiac Defects"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T18:04:23.205Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00165984",
      "title": "Influence of Genetic Polymorphisms on Ventricular Structure and Function in Patients With Single Ventricle Anatomy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 224,
      "start_date": "2004-01",
      "completion_date": "2010-08",
      "has_results": true,
      "last_update_posted_date": "2012-05-02",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00165984"
    },
    {
      "nct_id": "NCT06590467",
      "title": "Abbott Structural Heart Device Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Diseases",
        "ASD - Atrial Septal Defect",
        "VSD - Muscular Ventricular Septal Defect",
        "PFO - Patent Foramen Ovale",
        "PIVSD - Post Infarct Muscular Ventricular Septal Defect",
        "Valvular Heart Disease"
      ],
      "interventions": [
        {
          "name": "Amplatzer™ Occlusion Devices",
          "type": "DEVICE"
        },
        {
          "name": "Epic™ Surgical Tissue Heart Valve devices",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2500,
      "start_date": "2024-08-21",
      "completion_date": "2039-11",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 5,
      "location_summary": "New Brunswick, New Jersey • New York, New York • Philadelphia, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06590467"
    },
    {
      "nct_id": "NCT05514626",
      "title": "Three-dimensional (3D) Holographic Display for Ultrasound-Guided Structural Heart Disease Procedures",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Structural Cardiac Defects"
      ],
      "interventions": [
        {
          "name": "3D Holographic Display",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "RealView Imaging",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2022-03-24",
      "completion_date": "2023-06-30",
      "has_results": false,
      "last_update_posted_date": "2022-08-24",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05514626"
    },
    {
      "nct_id": "NCT06693674",
      "title": "Effect of Sacubitril-Valsartan on Cardiac Structure and Function",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Entresto Pill",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2025-02-03",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06693674"
    },
    {
      "nct_id": "NCT03482141",
      "title": "Clinical Utility of Prenatal Whole Exome Sequencing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Structural Anomalies",
        "Cardiac Anomalies",
        "Central Nervous System Anomalies",
        "Thorax Anomalies",
        "Genito-urinary Anomalies",
        "Gastrointestinal Anomalies",
        "Skeletal Anomalies",
        "Multiple Anomalies"
      ],
      "interventions": [
        {
          "name": "Whole Exome Sequencing (WES)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 316,
      "start_date": "2017-08-01",
      "completion_date": "2022-05-13",
      "has_results": true,
      "last_update_posted_date": "2023-04-14",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03482141"
    },
    {
      "nct_id": "NCT00564122",
      "title": "The Accuracy of an Artificially-intelligent Stethoscope",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Murmurs",
        "Congenital Heart Disease",
        "Structural Heart Disease"
      ],
      "interventions": [
        {
          "name": "Artificially-Intelligent Stethoscope",
          "type": "DEVICE"
        },
        {
          "name": "Physical Examination",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Akron Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 300,
      "start_date": "2007-12",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2011-11-01",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 3,
      "location_summary": "Akron, Ohio • Beachwood, Ohio • Boardman, Ohio",
      "locations": [
        {
          "city": "Akron",
          "state": "Ohio"
        },
        {
          "city": "Beachwood",
          "state": "Ohio"
        },
        {
          "city": "Boardman",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00564122"
    },
    {
      "nct_id": "NCT04950192",
      "title": "Philips Intracardiac Echocardiography (ICE) Clinical Registry",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Fibrillation",
        "Stroke",
        "Valve Disease, Heart",
        "Atrial Septal Defect",
        "Patent Foramen Ovale",
        "Mitral Valve Disease",
        "Tricuspid Valve Disease",
        "Aortic Valve Disease"
      ],
      "interventions": [
        {
          "name": "ICE Image guidance",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Clinical & Medical Affairs Global",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 155,
      "start_date": "2021-10-25",
      "completion_date": "2023-07-30",
      "has_results": true,
      "last_update_posted_date": "2025-01-06",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 5,
      "location_summary": "Aurora, Colorado • Chicago, Illinois • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04950192"
    },
    {
      "nct_id": "NCT03152773",
      "title": "Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Artery Hypertension",
        "Congenital Heart Disease",
        "Structural Heart Disease"
      ],
      "interventions": [
        {
          "name": "MRI Heart guidewire catheterization",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 22,
      "start_date": "2017-08-02",
      "completion_date": "2021-12-14",
      "has_results": true,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-07-22T18:04:23.205Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03152773"
    }
  ]
}