{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Subjective+Cognitive+Decline",
    "query": {
      "condition": "Subjective Cognitive Decline"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 40,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Subjective+Cognitive+Decline&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:10:43.457Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04005456",
      "title": "Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health, Subjective",
        "Gastrointestinal Dysfunction",
        "Cardiovascular Risk Factor",
        "Autoimmune Diseases",
        "Dental Diseases",
        "Hormone Disturbance",
        "Neurocognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Supplements and/or medical foods",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Behavioral change support program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Food plan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Metagenics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 400,
      "start_date": "2018-09-01",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-10-30",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Gig Harbor, Washington",
      "locations": [
        {
          "city": "Gig Harbor",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04005456"
    },
    {
      "nct_id": "NCT06340659",
      "title": "Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "At Risk for AD-dementia, With Subjective Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "HbAEx",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HbExergame",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "65 Years to 99 Years"
      },
      "enrollment_count": 104,
      "start_date": "2024-08-14",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-12",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06340659"
    },
    {
      "nct_id": "NCT06002477",
      "title": "Attentional Mechanisms in SCD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Subjective Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Mecamylamine Challenge",
          "type": "DRUG"
        },
        {
          "name": "Placebo Comparator Challenge",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2025-03-27",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-24",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06002477"
    },
    {
      "nct_id": "NCT06410807",
      "title": "Development of Web-Based Mind-Body Trainings for Adults With Subjective Concerns",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aging",
        "Focus Groups"
      ],
      "interventions": [
        {
          "name": "Focus groups",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2024-11-01",
      "completion_date": "2025-05-02",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06410807"
    },
    {
      "nct_id": "NCT02360917",
      "title": "Emerging From the Haze™- Measuring the Impact of a Psycho-education Program on Perceived Cognition After Breast Cancer Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognition",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Emerging from the Haze",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 31,
      "start_date": "2015-07-06",
      "completion_date": "2018-05-23",
      "has_results": false,
      "last_update_posted_date": "2018-11-01",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02360917"
    },
    {
      "nct_id": "NCT07395609",
      "title": "High Frequency Stimulation to Improve Cognition, Mobility, and Affect in Individuals With Subjective Cognitive Decline",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subjective Cognitive Decline (SCD)",
        "Healthy Subjects"
      ],
      "interventions": [
        {
          "name": "Flicker Stimulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Stimulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "40 Hz Visual Occlusion",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control - Visual Occlusion",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "65 Years to 89 Years"
      },
      "enrollment_count": 60,
      "start_date": "2026-05-15",
      "completion_date": "2028-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07395609"
    },
    {
      "nct_id": "NCT07130669",
      "title": "FACE Phase II (a Stage II Trial)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "MCI",
        "Subjective Cognitive Decline (SCD)",
        "Mild Behavioral Impairment"
      ],
      "interventions": [
        {
          "name": "Cognitive Remediation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Remediation II",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "60 Years to 89 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-10-31",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07130669"
    },
    {
      "nct_id": "NCT07019402",
      "title": "Internet-based Mind-Body Training for Brain Health",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subjective Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Internet-based Mindfulness-Based Stress Reduction (iMBSR)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Internet-based Lifestyle Education (iLifeEd)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-06-13",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07019402"
    },
    {
      "nct_id": "NCT05934136",
      "title": "Brain Health Program for Older Adults With Subjective Cognitive Decline",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Memory Loss (Excluding Dementia)",
        "Healthy Lifestyle",
        "Risk Reduction Behavior"
      ],
      "interventions": [
        {
          "name": "My Healthy Brain 1",
          "type": "BEHAVIORAL"
        },
        {
          "name": "My Healthy Brain 2",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-01-16",
      "completion_date": "2025-11-07",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05934136"
    },
    {
      "nct_id": "NCT02913664",
      "title": "Risk Reduction for Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Cognitively Normal Older Adults",
        "Hypertension",
        "Subjective Cognitive Decline",
        "Family History of Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine)",
          "type": "DRUG"
        },
        {
          "name": "Aerobic Exercise Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        },
        {
          "name": "Stretching Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 513,
      "start_date": "2017-02-02",
      "completion_date": "2022-01-31",
      "has_results": false,
      "last_update_posted_date": "2022-02-15",
      "last_synced_at": "2026-05-22T08:10:43.457Z",
      "location_count": 4,
      "location_summary": "Kansas City, Kansas • Baton Rouge, Louisiana • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02913664"
    }
  ]
}