{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Drug+Chronic",
    "query": {
      "condition": "Substance Abuse Drug Chronic"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 14,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Drug+Chronic&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:12:58.708Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06837662",
      "title": "The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Dependence",
        "Substance Abuse Disorders",
        "Complex Medical Patients",
        "Primary Care Patients With Chronic Conditions"
      ],
      "interventions": [
        {
          "name": "MOUD \"Plus\" Intervention (treatment as usual + coordinated counseling and referral to community based peer)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment As Usual (primary care with low threshold MOUD prescribing)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2025-03-24",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06837662"
    },
    {
      "nct_id": "NCT00612287",
      "title": "Sublingual Buprenorphine for Chronic Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "buprenorphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 40,
      "start_date": "2009-04",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2009-04-07",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00612287"
    },
    {
      "nct_id": "NCT00249587",
      "title": "Medication Adherence Therapy for Opioid Abusing Pain Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Pain",
        "Chronic Disease",
        "Prescription Opioid Abuse"
      ],
      "interventions": [
        {
          "name": "Methadone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2000-09",
      "completion_date": "2005-09",
      "has_results": false,
      "last_update_posted_date": "2017-01-10",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00249587"
    },
    {
      "nct_id": "NCT02955199",
      "title": "Stage III Community-based Efficacy Trial for Mothering From the Inside Out",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Addiction",
        "Substance Abuse Drug Chronic",
        "Child Neglect",
        "Child Neglect Emotional",
        "Child Abuse",
        "Parenting",
        "Parent-Child Problem",
        "Parent-Child Relations",
        "Parent / Child Problem",
        "Parenteral Drug Abuse",
        "Parents"
      ],
      "interventions": [
        {
          "name": "Mothering From the Inside Out (MIO)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Parent Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 97,
      "start_date": "2015-04",
      "completion_date": "2020-02",
      "has_results": false,
      "last_update_posted_date": "2021-07-14",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02955199"
    },
    {
      "nct_id": "NCT01857245",
      "title": "Intensive Models of HCV Care for Injection Drug Users",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hepatitis C",
        "Medication Adherence"
      ],
      "interventions": [
        {
          "name": "Intensive Models (mDOT and CGT) of HCV Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2013-10-01",
      "completion_date": "2017-04-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-03",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01857245"
    },
    {
      "nct_id": "NCT01003496",
      "title": "Comparing Acute and Continuous Drug Abuse Treatment: A Randomized Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Drug Addiction"
      ],
      "interventions": [
        {
          "name": "Treatment as Usual (TAU)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "TAU + Long-Term Recovery Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wright State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 204,
      "start_date": "2009-11-05",
      "completion_date": "2011-07-27",
      "has_results": false,
      "last_update_posted_date": "2022-03-09",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01003496"
    },
    {
      "nct_id": "NCT00596960",
      "title": "Study of the Effects of Motivational Enhancement Therapy on Alcohol Use in Chronic Hepatitis C Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Dependence",
        "Chronic Hepatitis C"
      ],
      "interventions": [
        {
          "name": "Motivational Enhancement Therapy (MET)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 139,
      "start_date": "2008-11",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2014-11-28",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 2,
      "location_summary": "Minneapolis, Minnesota • Portland, Oregon",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00596960"
    },
    {
      "nct_id": "NCT02583243",
      "title": "Project BEST: Buprenorphine Entry Into Substance Abuse Treatment",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Opioid-related Disorders",
        "HIV Infections",
        "Hepatitis C, Chronic",
        "Depression"
      ],
      "interventions": [
        {
          "name": "MET/CBT based individualized counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Buprenorphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 209,
      "start_date": "2005-05",
      "completion_date": "2008-08",
      "has_results": false,
      "last_update_posted_date": "2020-04-03",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02583243"
    },
    {
      "nct_id": "NCT02751762",
      "title": "A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Opioid-Related Disorders",
        "Opiate Addiction",
        "Narcotic Abuse",
        "Drug Abuse"
      ],
      "interventions": [
        {
          "name": "Observation Only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Member Companies of the Opioid PMR Consortium",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 3600,
      "start_date": "2017-11-01",
      "completion_date": "2023-01-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-29",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon • Seattle, Washington",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02751762"
    },
    {
      "nct_id": "NCT03947749",
      "title": "Linking Epigenomics With Prescription Opioid Abuse and High Impact Musculoskeletal Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pain, Chronic",
        "Prescription Drug Abuse (Not Dependent)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 275,
      "start_date": "2019-09-25",
      "completion_date": "2023-04-06",
      "has_results": false,
      "last_update_posted_date": "2023-08-14",
      "last_synced_at": "2026-05-22T08:12:58.708Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida • Jacksonville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03947749"
    }
  ]
}