{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Problem&page=3",
    "query": {
      "condition": "Substance Abuse Problem",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 505,
    "total_pages": 51,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Problem&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Problem&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-07T11:49:49.775Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00288886",
      "title": "Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Substance Use Disorders",
        "Alcohol Abuse",
        "Alcoholism",
        "Substance Dependence",
        "Substance Abuse"
      ],
      "interventions": [
        {
          "name": "Contracting, Prompting and Reinforcement arm",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control arm",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 183,
      "start_date": "2007-03",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2015-04-24",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 2,
      "location_summary": "Jackson, Mississippi • Salem, Virginia",
      "locations": [
        {
          "city": "Jackson",
          "state": "Mississippi"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00288886"
    },
    {
      "nct_id": "NCT00218725",
      "title": "Effectiveness of Cognitive Therapy for Suicide Attempters With Drug Dependence Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Suicide, Attempted",
        "Substance-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Cognitive Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enriched Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2005-05",
      "completion_date": "2005-10",
      "has_results": false,
      "last_update_posted_date": "2015-09-29",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00218725"
    },
    {
      "nct_id": "NCT03268759",
      "title": "Development of Reward Processing in Prenatally Exposed Adolescents and Young Adults",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pre-natal Cocaine Exposure",
        "Risk-Taking"
      ],
      "interventions": [
        {
          "name": "fMRI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "18 Years to 20 Years"
      },
      "enrollment_count": 78,
      "start_date": "2017-09-15",
      "completion_date": "2020-09-14",
      "has_results": false,
      "last_update_posted_date": "2021-05-04",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03268759"
    },
    {
      "nct_id": "NCT00000346",
      "title": "Cognitive Correlates of Substance Abuse - 11",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Amphetamine-Related Disorders"
      ],
      "interventions": [
        {
          "name": "counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 80,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-01-11",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000346"
    },
    {
      "nct_id": "NCT00734903",
      "title": "Women Veterans' Substance Abuse Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Use Disorders"
      ],
      "interventions": [
        {
          "name": "A Woman's Path to Recovery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "12-Step Facilitation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 66,
      "start_date": "2010-10",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2018-11-05",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 2,
      "location_summary": "Bedford, Massachusetts • Boston, Massachusetts",
      "locations": [
        {
          "city": "Bedford",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00734903"
    },
    {
      "nct_id": "NCT02487745",
      "title": "The Long-Term Treatment of Drug Addiction and Unemployment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Abuse, Intravenous"
      ],
      "interventions": [
        {
          "name": "Abstinence-contingent wage supplements",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Individual Placement and Support (IPS) supported employment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 91,
      "start_date": "2015-11",
      "completion_date": "2020-09",
      "has_results": true,
      "last_update_posted_date": "2022-08-11",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02487745"
    },
    {
      "nct_id": "NCT01539941",
      "title": "Family-Based Protocol for Medication Integration in Treatment of Comorbid ASU/ADHD in Routine Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Adolescent Substance Abuse",
        "Attention Deficit Hyperactivity Disorder"
      ],
      "interventions": [
        {
          "name": "Medication integration protocol",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The National Center on Addiction and Substance Abuse at Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 14,
      "start_date": "2011-08",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2015-08-04",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01539941"
    },
    {
      "nct_id": "NCT00223639",
      "title": "New Medications to Treat Alcohol Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alcoholism"
      ],
      "interventions": [
        {
          "name": "Topiramate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bankole Johnson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 29,
      "start_date": "2005-09",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2012-02-07",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 2,
      "location_summary": "Charlottesville, Virginia • Richmond, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00223639"
    },
    {
      "nct_id": "NCT01656837",
      "title": "Family-Based Treatment for Parental Substance Abuse and Child Maltreatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Abuse",
        "Child Abuse",
        "Child Neglect"
      ],
      "interventions": [
        {
          "name": "Comprehensive Community Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MST-BSF",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 191,
      "start_date": "2011-04",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2016-09-30",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 1,
      "location_summary": "New Britain, Connecticut",
      "locations": [
        {
          "city": "New Britain",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01656837"
    },
    {
      "nct_id": "NCT00842517",
      "title": "Long Term Maintenance of Drug Abstinence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cocaine Dependence",
        "Cocaine Abuse"
      ],
      "interventions": [
        {
          "name": "Contingency Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Treatment Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 166,
      "start_date": "2004-09",
      "completion_date": "2008-08",
      "has_results": false,
      "last_update_posted_date": "2023-03-28",
      "last_synced_at": "2026-11-07T11:49:49.775Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00842517"
    }
  ]
}