{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Problem&page=8",
    "query": {
      "condition": "Substance Abuse Problem",
      "page": 8
    },
    "page_size": 10
  },
  "pagination": {
    "page": 8,
    "page_size": 10,
    "total_count": 505,
    "total_pages": 51,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Problem&page=9&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Problem&page=7&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-07T12:57:13.736Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00367172",
      "title": "Directly Observed Antiretroviral Therapy Among Active Drug Users",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV/AIDS",
        "Substance Abuse"
      ],
      "interventions": [
        {
          "name": "Directly Administered Antiretroviral Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 125,
      "start_date": "2001-06",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2020-03-31",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00367172"
    },
    {
      "nct_id": "NCT00985595",
      "title": "Learning Effective Approaches to Prevention",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Adolescent Substance Abuse"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The National Center on Addiction and Substance Abuse at Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 200,
      "start_date": "2006-01",
      "completion_date": "2012-03",
      "has_results": false,
      "last_update_posted_date": "2015-08-05",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00985595"
    },
    {
      "nct_id": "NCT03695653",
      "title": "Messaging Interventions to Reduce Alcohol Problems Project",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol-Related Disorders",
        "Alcohol Use Disorders",
        "Alcohol Drinking",
        "Alcoholism",
        "Alcohol Abuse"
      ],
      "interventions": [
        {
          "name": "Drink Tracking (MA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Adaptive Tailored (TA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tailored (TO)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Partnership to End Addiction",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 730,
      "start_date": "2019-05-24",
      "completion_date": "2023-11-01",
      "has_results": false,
      "last_update_posted_date": "2021-06-29",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03695653"
    },
    {
      "nct_id": "NCT00957775",
      "title": "Computer-delivered Psychosocial Intervention for Adolescent Substance Use Disorders",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance-Related Disorders",
        "Alcohol-Related Disorders",
        "Marijuana Abuse"
      ],
      "interventions": [
        {
          "name": "Usual care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Computer-delivered ACRA",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Development and Research Institutes, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 84,
      "start_date": "2009-08",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2009-08-12",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00957775"
    },
    {
      "nct_id": "NCT01571167",
      "title": "Varenicline as a Treatment for Methamphetamine Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Methamphetamine Dependence",
        "Methamphetamine Abuse",
        "Substance Abuse"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 17,
      "start_date": "2011-01",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2013-06-13",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01571167"
    },
    {
      "nct_id": "NCT01621711",
      "title": "Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Abuse",
        "Substance Dependence",
        "Substance, Addiction",
        "Alcohol Abuse"
      ],
      "interventions": [
        {
          "name": "Linkage patient activation intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 504,
      "start_date": "2011-03",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-05-02",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01621711"
    },
    {
      "nct_id": "NCT04603781",
      "title": "CBD Oil for Reducing Emotional Impact of COVID-19",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Anxiety Depression",
        "Alcohol Abuse",
        "Substance Abuse",
        "Anger",
        "Sleep Disturbance",
        "Stress Reaction"
      ],
      "interventions": [
        {
          "name": "CBD Isolate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Full Spectrum CBD Oil",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Broad-Spectrum CBD Oil",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Oil",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 200,
      "start_date": "2020-12-04",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-22",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04603781"
    },
    {
      "nct_id": "NCT00227877",
      "title": "Screening and Brief Advice to Reduce Teen Substance Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Related Disorders"
      ],
      "interventions": [
        {
          "name": "cSBA - New England, USA",
          "type": "BEHAVIORAL"
        },
        {
          "name": "cSBA - Prague, CZR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 2695,
      "start_date": "2005-12",
      "completion_date": "2010-02",
      "has_results": true,
      "last_update_posted_date": "2019-08-14",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 5,
      "location_summary": "Boston, Massachusetts • Cambridge, Massachusetts • Worcester, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Concord",
          "state": "New Hampshire"
        },
        {
          "city": "Milton",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00227877"
    },
    {
      "nct_id": "NCT01362634",
      "title": "A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infection",
        "Substance Abuse"
      ],
      "interventions": [
        {
          "name": "Trans-theoretical Process of Change Model-self",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trans-theoretical Process of Change Model - interviewer",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Nova Southeastern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 750,
      "start_date": "2011-08",
      "completion_date": "2017-07-31",
      "has_results": false,
      "last_update_posted_date": "2017-12-07",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01362634"
    },
    {
      "nct_id": "NCT01381133",
      "title": "Adolescent Outpatient and Continuing Care Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Substance Abuse",
        "Substance Dependence"
      ],
      "interventions": [
        {
          "name": "Chestnut Bloomington Outpatient (CBOP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Assertive Continuing Care (ACC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Chestnut Health Systems",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 320,
      "start_date": "2002-09",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2013-08-14",
      "last_synced_at": "2026-11-07T12:57:13.736Z",
      "location_count": 1,
      "location_summary": "Bloomington, Illinois",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01381133"
    }
  ]
}