{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Relapse",
    "query": {
      "condition": "Substance Abuse Relapse"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 29,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Abuse+Relapse&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T09:30:50.275Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00944554",
      "title": "Relapse Prevention With Varenicline",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Recurrence",
        "Smoking Cessation",
        "Substance-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 104,
      "start_date": "2008-10",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2017-08-03",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00944554"
    },
    {
      "nct_id": "NCT01320748",
      "title": "fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Abuse",
        "Substance Dependence",
        "Alcohol Abuse",
        "Drug Use",
        "Relapse"
      ],
      "interventions": [
        {
          "name": "Dual Processing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Relapse Prevention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Inova Health Care Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2011-02",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2018-11-30",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Falls Church, Virginia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Falls Church",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01320748"
    },
    {
      "nct_id": "NCT01663337",
      "title": "Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PTSD",
        "Alcohol Abuse",
        "Alcohol Dependence"
      ],
      "interventions": [
        {
          "name": "Cognitive Processing Therapy (CPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Relapse Prevention (RP)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 235,
      "start_date": "2013-03",
      "completion_date": "2019-01",
      "has_results": false,
      "last_update_posted_date": "2018-07-18",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01663337"
    },
    {
      "nct_id": "NCT00373295",
      "title": "Effect of Baclofen on Marijuana Withdrawal and Relapse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Marijuana Dependence"
      ],
      "interventions": [
        {
          "name": "Baclofen",
          "type": "DRUG"
        },
        {
          "name": "Marijuana",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 13,
      "start_date": "2006-05",
      "completion_date": "2010-01",
      "has_results": true,
      "last_update_posted_date": "2017-05-10",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00373295"
    },
    {
      "nct_id": "NCT02125539",
      "title": "Field Trial of a Relapse Prevention Program for Adolescents Receiving Substance Use Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Substance-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Navigating my Journey program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Inflexxion, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "13 Years to 21 Years"
      },
      "enrollment_count": 160,
      "start_date": "2014-09",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-07-27",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "Newton, Massachusetts",
      "locations": [
        {
          "city": "Newton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02125539"
    },
    {
      "nct_id": "NCT00589641",
      "title": "Relapse Prevention for Suicidal Dually Diagnosed Youths",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Suicide, Attempted",
        "Suicide, Ideation",
        "Depression",
        "Substance Abuse"
      ],
      "interventions": [
        {
          "name": "CBT-RP (relapse prevention) + Enhanced TAU",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced TAU Alone",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "13 Years to 19 Years"
      },
      "enrollment_count": 13,
      "start_date": "2005-07",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2014-07-10",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00589641"
    },
    {
      "nct_id": "NCT06415721",
      "title": "Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use Disorder",
        "Alcohol Abuse",
        "Alcoholism",
        "Drinking Behavior",
        "Drinking Problem"
      ],
      "interventions": [
        {
          "name": "Active Transcranial Magnetic Simulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Palo Alto Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-08-25",
      "completion_date": "2026-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-13",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06415721"
    },
    {
      "nct_id": "NCT00218075",
      "title": "Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cocaine Abuse",
        "Cocaine-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Levodopa",
          "type": "DRUG"
        },
        {
          "name": "Carbidopa",
          "type": "DRUG"
        },
        {
          "name": "Clinical Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Relapse Prevention Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Contingency Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 200,
      "start_date": "2000-03",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2016-01-05",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00218075"
    },
    {
      "nct_id": "NCT01035632",
      "title": "Study of Smoking Abstinence",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Substance Abuse Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2006-04-07",
      "completion_date": "2011-01-12",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01035632"
    },
    {
      "nct_id": "NCT01967641",
      "title": "Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Opioid Dependence"
      ],
      "interventions": [
        {
          "name": "buprenorphine/naloxone combination",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 51,
      "start_date": "2005-11",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2019-04-24",
      "last_synced_at": "2026-07-23T09:30:50.275Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01967641"
    }
  ]
}