{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Misuse&page=11",
    "query": {
      "condition": "Substance Misuse",
      "page": 11
    },
    "page_size": 10
  },
  "pagination": {
    "page": 11,
    "page_size": 10,
    "total_count": 258,
    "total_pages": 26,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Misuse&page=12&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Substance+Misuse&page=10&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T17:37:54.722Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06456294",
      "title": "Evaluation of a Medication Health Center to Promote Opioid Safety",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overdose"
      ],
      "interventions": [
        {
          "name": "MHC Outreach Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2022-06-15",
      "completion_date": "2025-01-01",
      "has_results": false,
      "last_update_posted_date": "2024-06-14",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06456294"
    },
    {
      "nct_id": "NCT05142267",
      "title": "Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid Use Disorder",
        "Back Pain",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone",
          "type": "DRUG"
        },
        {
          "name": "Naloxone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 101,
      "start_date": "2022-03-02",
      "completion_date": "2026-04-07",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05142267"
    },
    {
      "nct_id": "NCT03495245",
      "title": "Identification of Potential Biomarkers for Pain",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fibromyalgia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rowan University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2018-03-28",
      "completion_date": "2021-09-30",
      "has_results": false,
      "last_update_posted_date": "2019-11-19",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Stratford, New Jersey",
      "locations": [
        {
          "city": "Stratford",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03495245"
    },
    {
      "nct_id": "NCT06273228",
      "title": "Parenting Young Children in Pediatrics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parenting",
        "Parent-Child Relations",
        "Substance Use Disorders",
        "Stress",
        "Depression",
        "Anxiety",
        "Parenting Self-efficacy",
        "Pediatrics"
      ],
      "interventions": [
        {
          "name": "Family Check-Up Online",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oregon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 18,
      "start_date": "2023-09-27",
      "completion_date": "2024-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-03-14",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06273228"
    },
    {
      "nct_id": "NCT07797933",
      "title": "A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk Aim 3",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overdose"
      ],
      "interventions": [
        {
          "name": "Brief youth overdose prevention education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 648,
      "start_date": "2026-11",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2026-10-01",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07797933"
    },
    {
      "nct_id": "NCT03337100",
      "title": "The Impact of Co-Dispensing Naloxone to Patients Prescribed Chronic Opioid Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overdose",
        "Risk Behavior"
      ],
      "interventions": [
        {
          "name": "Co-Dispensing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2017-11-27",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-03-03",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03337100"
    },
    {
      "nct_id": "NCT03972163",
      "title": "Standardized Patient-Centered Medication Review in Home Hospice",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hospices",
        "Poly Pharmacy",
        "Deprescriptions",
        "Caregivers",
        "Palliative Care",
        "Prescription Drug Overuse",
        "Interdisciplinary Communication"
      ],
      "interventions": [
        {
          "name": "NIA Medication Management - Active Comparator",
          "type": "BEHAVIORAL"
        },
        {
          "name": "STOPPFrail (Screening Tool of Older Persons Prescriptions)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "\"Discontinuing Medication Appropriately\" and \"Understanding the Art of Communication about Deprescribing\"",
          "type": "BEHAVIORAL"
        },
        {
          "name": "\"Key Approaches to Support Informal Family Caregivers in Managing Medications\"",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Massachusetts, Worcester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "65 Years to 110 Years"
      },
      "enrollment_count": 23,
      "start_date": "2020-01-15",
      "completion_date": "2023-12-31",
      "has_results": true,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Danvers, Massachusetts",
      "locations": [
        {
          "city": "Danvers",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03972163"
    },
    {
      "nct_id": "NCT01849029",
      "title": "Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post Traumatic Stress Disorders",
        "Unsafe Sex",
        "Substance Use Disorders"
      ],
      "interventions": [
        {
          "name": "Cognitive Processing Therapy-Cognitive",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2013-10-15",
      "completion_date": "2017-07-30",
      "has_results": false,
      "last_update_posted_date": "2017-08-22",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Toppenish, Washington",
      "locations": [
        {
          "city": "Toppenish",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01849029"
    },
    {
      "nct_id": "NCT05362357",
      "title": "iSTART: A Campus & Community Initiative for Services in Tec-health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Use",
        "Binge Drinking",
        "Marijuana Use",
        "Alcohol Drinking",
        "Prescription Opioid Misuse",
        "Illicit Drug Use"
      ],
      "interventions": [
        {
          "name": "iSTART Web-app",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "California State University, Northridge",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 1100,
      "start_date": "2021-02-20",
      "completion_date": "2023-12-04",
      "has_results": false,
      "last_update_posted_date": "2024-02-07",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Northridge, California",
      "locations": [
        {
          "city": "Northridge",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05362357"
    },
    {
      "nct_id": "NCT02660606",
      "title": "A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Opioid-Related Disorders",
        "Opiate Addiction",
        "Narcotic Abuse",
        "Drug Abuse"
      ],
      "interventions": [
        {
          "name": "Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Member Companies of the Opioid PMR Consortium",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2015-01-02",
      "completion_date": "2016-01-18",
      "has_results": false,
      "last_update_posted_date": "2020-04-15",
      "last_synced_at": "2026-10-23T17:37:54.722Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02660606"
    }
  ]
}