{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Superimposed+Preeclampsia",
    "query": {
      "condition": "Superimposed Preeclampsia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Superimposed+Preeclampsia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:43:47.350Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03815110",
      "title": "Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preeclampsia and Eclampsia",
        "Preeclampsia Severe",
        "Gestational Hypertension",
        "Chronic Hypertension in Obstetric Context",
        "Superimposed Pre-Eclampsia",
        "Preeclampsia Mild"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1050,
      "start_date": "2018-12-20",
      "completion_date": "2022-10-01",
      "has_results": false,
      "last_update_posted_date": "2022-11-28",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 18,
      "location_summary": "Los Angeles, California • San Diego, California • San Francisco, California + 13 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03815110"
    },
    {
      "nct_id": "NCT02213094",
      "title": "Phase I Study of Nicotinamide for Early Onset Preeclampsia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pregnancy Induced Hypertension",
        "Superimposed Preeclampsia",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Nicotinamide 500 mg",
          "type": "DRUG"
        },
        {
          "name": "Nicotinamide 1000 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2014-01-01",
      "completion_date": "2015-12-03",
      "has_results": true,
      "last_update_posted_date": "2018-11-02",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02213094"
    },
    {
      "nct_id": "NCT06785116",
      "title": "A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gestational Hypertension",
        "Hypertension in Pregnancy",
        "Pre-Eclampsia",
        "Superimposed Pre-Eclampsia",
        "Cardiovascular Complication"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Dapagliflozin 10mg Tab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2025-03-02",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-04",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06785116"
    },
    {
      "nct_id": "NCT06359015",
      "title": "Metformin and Esomeprazole in Preterm Pre-eclampsia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preeclampsia Severe",
        "Pre-Eclampsia",
        "Preeclampsia",
        "Preeclampsia Second Trimester",
        "Preeclampsia Complicating Childbirth",
        "Preeclampsia Puerperium",
        "Preterm"
      ],
      "interventions": [
        {
          "name": "Metformin",
          "type": "DRUG"
        },
        {
          "name": "Esomeprazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Christiana Care Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 4,
      "start_date": "2021-02-11",
      "completion_date": "2025-05-08",
      "has_results": false,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06359015"
    },
    {
      "nct_id": "NCT03824119",
      "title": "Postpartum NSAIDS and Maternal Hypertension",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preeclampsia",
        "Gestational Hypertension",
        "Superimposed Preeclampsia",
        "Chronic Hypertension in Obstetric Context"
      ],
      "interventions": [
        {
          "name": "Ibuprofen 600 mg",
          "type": "DRUG"
        },
        {
          "name": "Standard Postpartum Care without NSAIDs",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2018-12-11",
      "completion_date": "2022-12-11",
      "has_results": false,
      "last_update_posted_date": "2020-11-06",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03824119"
    },
    {
      "nct_id": "NCT04660032",
      "title": "Nudge to Drive Transitions of Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preeclampsia",
        "Preeclampsia Severe",
        "Gestational Hypertension",
        "Hypertensive Disorder of Pregnancy",
        "Superimposed Pre-Eclampsia"
      ],
      "interventions": [
        {
          "name": "Nudge",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 224,
      "start_date": "2021-02-08",
      "completion_date": "2023-04-20",
      "has_results": true,
      "last_update_posted_date": "2024-08-05",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04660032"
    },
    {
      "nct_id": "NCT02989025",
      "title": "Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pregnancy",
        "Preeclampsia (PE)"
      ],
      "interventions": [
        {
          "name": "17 OHPC",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Mississippi Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2017-05-22",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Jackson, Mississippi",
      "locations": [
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02989025"
    },
    {
      "nct_id": "NCT03441711",
      "title": "sFlt-1:PlGF Ratio in Diagnosing Superimposed Preeclampsia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preeclampsia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 45 Years · Female only"
      },
      "enrollment_count": 87,
      "start_date": "2016-02",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2020-11-13",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03441711"
    },
    {
      "nct_id": "NCT03298802",
      "title": "Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pre-Eclampsia",
        "Gestational Hypertension",
        "Superimposed Pre-Eclampsia",
        "Hypertension, Pregnancy-Induced",
        "Postpartum Pregnancy-Induced Hypertension",
        "Postpartum Preeclampsia"
      ],
      "interventions": [
        {
          "name": "Hydrochlorothiazide 50mg Tablet",
          "type": "DRUG"
        },
        {
          "name": "Placebo Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 612,
      "start_date": "2017-11-21",
      "completion_date": "2024-08-30",
      "has_results": false,
      "last_update_posted_date": "2023-12-05",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 2,
      "location_summary": "Austin, Texas • Galveston, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03298802"
    },
    {
      "nct_id": "NCT02920593",
      "title": "A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gestational Hypertension",
        "Toxemia",
        "Superimposed Preeclampsia",
        "Eclampsia",
        "HELLP Syndrome"
      ],
      "interventions": [
        {
          "name": "Vitamin D3",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 412,
      "start_date": "2016-10",
      "completion_date": "2019-03-31",
      "has_results": false,
      "last_update_posted_date": "2017-10-05",
      "last_synced_at": "2026-05-22T05:43:47.350Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02920593"
    }
  ]
}