{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Surfactant",
    "query": {
      "condition": "Surfactant"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Surfactant&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:44:29.086Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04659122",
      "title": "A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection or Severed Community Acquired Pneumonia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "COVID-19",
        "Undefined"
      ],
      "interventions": [
        {
          "name": "AT-100",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Airway Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2021-08-17",
      "completion_date": "2023-02-23",
      "has_results": false,
      "last_update_posted_date": "2023-08-14",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04659122"
    },
    {
      "nct_id": "NCT01203358",
      "title": "Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Exosurf",
          "type": "DRUG"
        },
        {
          "name": "Survanta",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "Up to 6 Hours"
      },
      "enrollment_count": 617,
      "start_date": "1991-01",
      "completion_date": "1992-01",
      "has_results": false,
      "last_update_posted_date": "2019-03-22",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 13,
      "location_summary": "Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01203358"
    },
    {
      "nct_id": "NCT06074380",
      "title": "Non Inferiority Trial Investigating Surfactants Administered Via MIST",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "MIST surfactant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "48 Hours",
        "sex": "ALL",
        "summary": "Up to 48 Hours"
      },
      "enrollment_count": 262,
      "start_date": "2024-01-01",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-07",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 1,
      "location_summary": "Evanston, Illinois",
      "locations": [
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06074380"
    },
    {
      "nct_id": "NCT07176117",
      "title": "Surfactant Using a Supraglottic Airway Device in Late Preterm to Early Term Infants",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome (Neonatal)",
        "Surfactant"
      ],
      "interventions": [
        {
          "name": "Surfactant Administration Through Laryngeal or Supraglottic Airway (SALSA)",
          "type": "PROCEDURE"
        },
        {
          "name": "Continuous Positive Airway Pressure (CPAP)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Sharp HealthCare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "33 Weeks",
        "maximum_age": "38 Weeks",
        "sex": "ALL",
        "summary": "33 Weeks to 38 Weeks"
      },
      "enrollment_count": 422,
      "start_date": "2025-11-20",
      "completion_date": "2031-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 3,
      "location_summary": "Chula Vista, California • La Mesa, California • San Diego, California",
      "locations": [
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07176117"
    },
    {
      "nct_id": "NCT00014859",
      "title": "Epidemiology of Surfactant Protein-B Deficiency",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lung Diseases",
        "Respiratory Distress Syndrome, Newborn",
        "Pulmonary Surfactant",
        "Lung Diseases, Interstitial"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 5176,
      "start_date": "2001-06-01",
      "completion_date": "2024-04-26",
      "has_results": false,
      "last_update_posted_date": "2024-04-29",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00014859"
    },
    {
      "nct_id": "NCT02615912",
      "title": "A Single-Center, Exploratory Study to Analyze the Dynamics of Skin Microflora Following Exposure to Surfactants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dermatitis"
      ],
      "interventions": [
        {
          "name": "PEG-40 Hydrogenated Castor Oil (Tagat CH40, Evonik) 1.5%",
          "type": "OTHER"
        },
        {
          "name": "Lauryl glucoside (Plantacare® 1200UP, BASF) 1.5%",
          "type": "OTHER"
        },
        {
          "name": "Sorbitan palmitate (SPANTM 40 (powder), Croda) 1.5%",
          "type": "OTHER"
        },
        {
          "name": "Silwet* DA-63 (Momentive) 1.5%",
          "type": "OTHER"
        },
        {
          "name": "Sodium lauryl sulfate (Sigma Aldrich) 1.0%",
          "type": "OTHER"
        },
        {
          "name": "Water (control)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kimberly-Clark Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 24,
      "start_date": "2015-11",
      "completion_date": "2016-02",
      "has_results": false,
      "last_update_posted_date": "2016-09-28",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 1,
      "location_summary": "Irving, Texas",
      "locations": [
        {
          "city": "Irving",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02615912"
    },
    {
      "nct_id": "NCT06776783",
      "title": "Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Distress Syndrome",
        "Pre-term Infants"
      ],
      "interventions": [
        {
          "name": "APC-0101 (SF-RI 1 surfactant for inhalation combined with a dedicated delivery system)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "OTHER"
      ],
      "sponsor": "Aerogen Pharma Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 520,
      "start_date": "2025-09-24",
      "completion_date": "2029-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 12,
      "location_summary": "Little Rock, Arkansas • La Jolla, California • Jacksonville, Florida + 9 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "South Bend",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06776783"
    },
    {
      "nct_id": "NCT02452476",
      "title": "A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "CHF5633",
          "type": "DRUG"
        },
        {
          "name": "Poractant alfa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chiesi Farmaceutici S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 123,
      "start_date": "2016-01-21",
      "completion_date": "2018-05-24",
      "has_results": true,
      "last_update_posted_date": "2021-08-13",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 23,
      "location_summary": "Mobile, Alabama • Los Angeles, California • Orange, California + 20 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02452476"
    },
    {
      "nct_id": "NCT00233324",
      "title": "Surfactant Positive Airway Pressure and Pulse Oximetry Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn, Diseases",
        "Other Preterm Infants",
        "Infant, Small for Gestational Age",
        "Premature Birth",
        "Bronchopulmonary Dysplasia",
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Surfactant",
          "type": "DRUG"
        },
        {
          "name": "Continuous Positive Airway Pressure (CPAP)",
          "type": "DEVICE"
        },
        {
          "name": "Supplemental oxygen with target saturation of 85 to 89%",
          "type": "DRUG"
        },
        {
          "name": "Supplemental oxygen with target saturation of 91 to 95%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Weeks",
        "maximum_age": "27 Weeks",
        "sex": "ALL",
        "summary": "24 Weeks to 27 Weeks"
      },
      "enrollment_count": 1316,
      "start_date": "2005-02",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2019-04-18",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 22,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00233324"
    },
    {
      "nct_id": "NCT05094700",
      "title": "A Study of a Polymeric Surfactant Technology Cleanser in Sensitive Skin Participants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dermatitis, Atopic",
        "Rosacea",
        "Acne Vulgaris",
        "Sensitive Skin"
      ],
      "interventions": [
        {
          "name": "Non-marketed Cosmetic Facial Cleanser",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 85,
      "start_date": "2021-10-25",
      "completion_date": "2021-11-30",
      "has_results": false,
      "last_update_posted_date": "2022-11-23",
      "last_synced_at": "2026-05-22T06:44:29.086Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05094700"
    }
  ]
}