{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Surgery+for+Congenital+Heart+Disease&page=2",
    "query": {
      "condition": "Surgery for Congenital Heart Disease",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Surgery+for+Congenital+Heart+Disease&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T18:06:00.175Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02891837",
      "title": "L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Lung Injury"
      ],
      "interventions": [
        {
          "name": "L-citrulline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Asklepion Pharmaceuticals, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 189,
      "start_date": "2016-08",
      "completion_date": "2019-07",
      "has_results": true,
      "last_update_posted_date": "2023-02-23",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 20,
      "location_summary": "Birmingham, Alabama • Loma Linda, California • Sacramento, California + 16 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02891837"
    },
    {
      "nct_id": "NCT04017975",
      "title": "Optical Tissue Identification for Myocardial Architecture",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ventricular Septal Defect",
        "Complete Atrioventricular Canal",
        "Tetralogy of Fallot With Pulmonary Stenosis"
      ],
      "interventions": [
        {
          "name": "Fluorescite",
          "type": "DRUG"
        },
        {
          "name": "Cellvizio 100 Series System with Confocal Miniprobes",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Aditya Kaza",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "30 Days to 18 Years"
      },
      "enrollment_count": 70,
      "start_date": "2019-12-20",
      "completion_date": "2023-09",
      "has_results": false,
      "last_update_posted_date": "2023-06-15",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04017975"
    },
    {
      "nct_id": "NCT03078413",
      "title": "Late Function After Surgery for Transposition of the Great Arteries",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transposition of Great Vessels"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2017-03-03",
      "completion_date": "2018-06-30",
      "has_results": false,
      "last_update_posted_date": "2018-11-19",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03078413"
    },
    {
      "nct_id": "NCT05006404",
      "title": "Autus Valve Pivotal Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Pulmonary Valve Replacement Surgery",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "18 Months to 16 Years"
      },
      "enrollment_count": 51,
      "start_date": "2024-02-05",
      "completion_date": "2036-02-05",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 12,
      "location_summary": "Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 9 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05006404"
    },
    {
      "nct_id": "NCT00278005",
      "title": "Infection in DiGeorge Following CHD Surgery",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "DiGeorge Syndrome",
        "Congenital Heart Defects"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Healthcare of Atlanta",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "Up to 15 Years"
      },
      "enrollment_count": 400,
      "start_date": "1998-01",
      "completion_date": "2008-03",
      "has_results": false,
      "last_update_posted_date": "2012-03-16",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00278005"
    },
    {
      "nct_id": "NCT06833320",
      "title": "Propranolol Treatment for Postoperative Chylothorax",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Chylothorax",
        "Congenital Heart Disease",
        "Open Heart Surgery",
        "Chylothorax"
      ],
      "interventions": [
        {
          "name": "Propranolol Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "June Wu",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "7 Days to 18 Years"
      },
      "enrollment_count": 50,
      "start_date": "2025-09-09",
      "completion_date": "2031-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06833320"
    },
    {
      "nct_id": "NCT00608140",
      "title": "Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mitral Valve Insufficiency",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Surgical mitral valvuloplasty with placement of annular ring (SMVR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Optimal medical therapy (OMT)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2008-03",
      "completion_date": "2010-03",
      "has_results": true,
      "last_update_posted_date": "2018-04-04",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 8,
      "location_summary": "Atlanta, Georgia • Boston, Massachusetts • Minneapolis, Minnesota + 5 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00608140"
    },
    {
      "nct_id": "NCT00513240",
      "title": "Erythropoetin Neuroprotection for Neonatal Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Congenital Heart Disease",
        "Hypoplastic Left Heart Syndrome",
        "Transposition of the Great Arteries",
        "Aortic Arch Hypoplasia or Interruption"
      ],
      "interventions": [
        {
          "name": "Erythropoetin",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "1 Day to 30 Days"
      },
      "enrollment_count": 62,
      "start_date": "2006-09",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2020-02-07",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00513240"
    },
    {
      "nct_id": "NCT03882450",
      "title": "Universal Screening for Vocal Fold Motion Impairment in Children Undergoing Congenital Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vocal Fold Palsy",
        "Dysphagia",
        "Congenital Heart Disease in Children"
      ],
      "interventions": [
        {
          "name": "Flexible fiberoptic laryngoscopy",
          "type": "PROCEDURE"
        },
        {
          "name": "Laryngeal ultrasonography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 94,
      "start_date": "2019-01-01",
      "completion_date": "2020-03-13",
      "has_results": false,
      "last_update_posted_date": "2020-04-14",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03882450"
    },
    {
      "nct_id": "NCT05253209",
      "title": "A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ventricular Septal Defect",
        "Atrioventricular Septal Defect",
        "Primum Atrial Septal Defect"
      ],
      "interventions": [
        {
          "name": "L-citrulline",
          "type": "DRUG"
        },
        {
          "name": "Plasmalyte A",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Asklepion Pharmaceuticals, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 64,
      "start_date": "2022-06-29",
      "completion_date": "2024-05-10",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-07-23T18:06:00.175Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Aurora, Colorado • Chicago, Illinois + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05253209"
    }
  ]
}