{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=13",
    "query": {
      "condition": "Symptoms of Depression and Anxiety",
      "page": 13
    },
    "page_size": 10
  },
  "pagination": {
    "page": 13,
    "page_size": 10,
    "total_count": 600,
    "total_pages": 60,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=14&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=12&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T18:24:55.921Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07025486",
      "title": "Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Depression, Anxiety"
      ],
      "interventions": [
        {
          "name": "HabitWorks",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Symptom TRacking",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mclean Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 340,
      "start_date": "2024-03-13",
      "completion_date": "2025-04-04",
      "has_results": false,
      "last_update_posted_date": "2025-06-17",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "Belmont, Massachusetts",
      "locations": [
        {
          "city": "Belmont",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07025486"
    },
    {
      "nct_id": "NCT07852728",
      "title": "HBOT Effects on First Responders' Cognition and Well-Being",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Traumatic Brain Injury",
        "PTSD - Post Traumatic Stress Disorder",
        "Anxiety",
        "Depression",
        "Post Concussion Symptoms"
      ],
      "interventions": [
        {
          "name": "Hyperbaric Oxygen Therapy (HBOT)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Summit Hyperbarics and Wellness",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 54,
      "start_date": "2026-09-11",
      "completion_date": "2027-09-11",
      "has_results": false,
      "last_update_posted_date": "2026-10-01",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "Boise, Idaho",
      "locations": [
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07852728"
    },
    {
      "nct_id": "NCT07161700",
      "title": "An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder (MDD)",
        "Major Depressive Disorder With Anxious Distress"
      ],
      "interventions": [
        {
          "name": "SPT-300",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seaport Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "66 Years",
        "sex": "ALL",
        "summary": "18 Years to 66 Years"
      },
      "enrollment_count": 360,
      "start_date": "2025-09-02",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-10-06",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 20,
      "location_summary": "Chino, California • Garden Grove, California • Glendale, California + 17 more",
      "locations": [
        {
          "city": "Chino",
          "state": "California"
        },
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Cromwell",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07161700"
    },
    {
      "nct_id": "NCT05559749",
      "title": "Collaborative Care for Anxiety and Depression in Epilepsy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy",
        "Anxiety",
        "Depression"
      ],
      "interventions": [
        {
          "name": "collaborative care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "usual neurology care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-05-04",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05559749"
    },
    {
      "nct_id": "NCT06502483",
      "title": "PRISM for Depression and Anxiety in Young Adults With Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer Diagnosis",
        "Non-Metastatic Neoplasm",
        "Anxiety",
        "Anxiety Disorders",
        "Depression",
        "Depressive Disorder",
        "Depression, Anxiety",
        "Desmoid"
      ],
      "interventions": [
        {
          "name": "Promoting Resilience in Stress Management Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Dana-Farber Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 13,
      "start_date": "2024-09-06",
      "completion_date": "2026-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "Brighton, Massachusetts",
      "locations": [
        {
          "city": "Brighton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06502483"
    },
    {
      "nct_id": "NCT06149429",
      "title": "Virtual Reality at End-of-life",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End of Life",
        "Pain",
        "Nausea",
        "Fatigue",
        "Well-Being, Psychological",
        "Depression",
        "Dyspnea",
        "Appetite Loss",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Personalized virtual reality experience",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 9,
      "start_date": "2023-10-23",
      "completion_date": "2024-07-15",
      "has_results": false,
      "last_update_posted_date": "2024-12-19",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "Cheektowaga, New York",
      "locations": [
        {
          "city": "Cheektowaga",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06149429"
    },
    {
      "nct_id": "NCT01084694",
      "title": "Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression",
        "Anxiety",
        "Fatigue",
        "Distress"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northside Hospital, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2010-04-19",
      "completion_date": "2018-03-30",
      "has_results": true,
      "last_update_posted_date": "2020-01-07",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01084694"
    },
    {
      "nct_id": "NCT02660385",
      "title": "Insomnia Self-Management in Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Failure",
        "Heart Failure",
        "Congestive Heart Failure",
        "Heart Failure, Congestive",
        "Sleep Initiation and Maintenance Disorders",
        "Chronic Insomnia",
        "Disorders of Initiating and Maintaining Sleep",
        "Fatigue",
        "Pain",
        "Depressive Symptoms",
        "Sleep Disorders",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-Management Education for Heart Failure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 195,
      "start_date": "2016-03-07",
      "completion_date": "2021-11-30",
      "has_results": true,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02660385"
    },
    {
      "nct_id": "NCT06594848",
      "title": "Effects of a Black Rice Extract and Anthocyanidin Metabolites on the Synthesis and Release of BDNF in Healthy Subjects",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognition - Other",
        "Depression, Anxiety"
      ],
      "interventions": [
        {
          "name": "Black rice extract",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 12,
      "start_date": "2024-09-15",
      "completion_date": "2026-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06594848"
    },
    {
      "nct_id": "NCT01825746",
      "title": "Goal Setting for Health Behavior and Psychosocial Issues in Primary Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health Behaviors",
        "Obesity",
        "Substance Abuse",
        "Anxiety",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Implementation of the MOHR assessment in primary care workflow",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 3591,
      "start_date": "2013-03",
      "completion_date": "2014-02",
      "has_results": false,
      "last_update_posted_date": "2015-05-13",
      "last_synced_at": "2026-10-22T18:24:55.921Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Chapel Hill, North Carolina • Portland, Oregon + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "College Station",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01825746"
    }
  ]
}