{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=2",
    "query": {
      "condition": "Symptoms of Depression and Anxiety",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T23:14:15.175Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05264415",
      "title": "Intergenerational Transmission of Traumatic Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress, Psychological",
        "Stress Disorders, Traumatic",
        "Emotion Regulation",
        "Behavior, Child",
        "Emotional Stress",
        "Trauma, Psychological",
        "Anxiety",
        "Depression",
        "Coping Skills",
        "Parent-Child Relations",
        "Parenting"
      ],
      "interventions": [
        {
          "name": "Families OverComing Under Stress (FOCUS) for Early Childhood (FOCUS-EC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Parenting Education Website",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "3 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2021-10-06",
      "completion_date": "2024-11-04",
      "has_results": false,
      "last_update_posted_date": "2024-11-29",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05264415"
    },
    {
      "nct_id": "NCT03904186",
      "title": "Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus",
        "Smoking Cessation",
        "Smoking, Cigarette",
        "Smoking",
        "Anxiety",
        "Depression",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "QUIT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Time-Matched Control (TM)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 131,
      "start_date": "2019-12-19",
      "completion_date": "2025-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Houston, Texas",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03904186"
    },
    {
      "nct_id": "NCT05065476",
      "title": "Assessing the Impact of Isha Kriya Meditation on Anxiety and Depression - a Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anxiety",
        "Depression"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 267,
      "start_date": "2021-05-01",
      "completion_date": "2021-11-30",
      "has_results": false,
      "last_update_posted_date": "2022-12-05",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05065476"
    },
    {
      "nct_id": "NCT04226742",
      "title": "Evaluation of a Crowd-Powered Web Platform for Depression and Anxiety",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression, Anxiety"
      ],
      "interventions": [
        {
          "name": "ADAPT Platform (Treatment)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "ADAPT Comparison (Control)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2021-02-18",
      "completion_date": "2022-01-04",
      "has_results": true,
      "last_update_posted_date": "2023-06-29",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04226742"
    },
    {
      "nct_id": "NCT01496612",
      "title": "Buspirone Therapy for Localized Epilepsy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anxiety Disorder",
        "Seizures",
        "Epilepsy",
        "Partial Epilepsy",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Buspirone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 9,
      "start_date": "2011-11-22",
      "completion_date": "2016-04-19",
      "has_results": true,
      "last_update_posted_date": "2021-10-05",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01496612"
    },
    {
      "nct_id": "NCT01680172",
      "title": "Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cancer",
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2012-08",
      "completion_date": "2015-02",
      "has_results": true,
      "last_update_posted_date": "2016-02-29",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 2,
      "location_summary": "Scottsdale, Arizona • Yuma, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Yuma",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01680172"
    },
    {
      "nct_id": "NCT04032301",
      "title": "Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Post-Traumatic Stress Disorders",
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 67,
      "start_date": "2019-09-30",
      "completion_date": "2024-11-10",
      "has_results": false,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04032301"
    },
    {
      "nct_id": "NCT05523414",
      "title": "The Effect of SKY Breath Meditation on Health and Well-being",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress",
        "Stress, Psychological",
        "Stress, Physiological",
        "Anxiety",
        "Mental Well Being",
        "Happiness",
        "Resilience"
      ],
      "interventions": [
        {
          "name": "SKY",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 45,
      "start_date": "2023-04-01",
      "completion_date": "2024-09-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05523414"
    },
    {
      "nct_id": "NCT02537093",
      "title": "Pilot Study of Asynchronous and Synchronous Telepsychiatry for Skilled Nursing Facilities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Depression",
        "Mood Disorder",
        "Anxiety Disorder",
        "Substance Use Disorder"
      ],
      "interventions": [
        {
          "name": "Psychiatric Consultation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2015-08",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2017-07-11",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 2,
      "location_summary": "Sacramento, California • Woodland, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Woodland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02537093"
    },
    {
      "nct_id": "NCT07375485",
      "title": "Occupational Therapy for Mental Health and Engagement in Neurorehabilitation",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acquired Brain Injury",
        "Mental Health",
        "Depressive Symptoms",
        "Anxiety Symptoms",
        "Loneliness"
      ],
      "interventions": [
        {
          "name": "Multifaceted implementation program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Colorado State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-07-01",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-07-23T23:14:15.175Z",
      "location_count": 2,
      "location_summary": "Denver, Colorado • Fort Collins, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07375485"
    }
  ]
}