{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=21",
    "query": {
      "condition": "Symptoms of Depression and Anxiety",
      "page": 21
    },
    "page_size": 10
  },
  "pagination": {
    "page": 21,
    "page_size": 10,
    "total_count": 600,
    "total_pages": 60,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=22&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Symptoms+of+Depression+and+Anxiety&page=20&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-25T12:54:18.578Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02614443",
      "title": "Effectiveness and Acceptability of Internet-delivered Treatment for Depression, Anxiety and Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anxiety",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Space from Depression",
          "type": "OTHER"
        },
        {
          "name": "Space from Anxiety",
          "type": "OTHER"
        },
        {
          "name": "Space from Stress",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Silver Cloud Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2015-10",
      "completion_date": "2017-09",
      "has_results": false,
      "last_update_posted_date": "2018-09-11",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02614443"
    },
    {
      "nct_id": "NCT05016050",
      "title": "Digital Therapeutic for Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Generalized Anxiety Disorder"
      ],
      "interventions": [
        {
          "name": "HPDT-DA-013",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Happify Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 367,
      "start_date": "2021-08-09",
      "completion_date": "2023-04-14",
      "has_results": false,
      "last_update_posted_date": "2023-06-01",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05016050"
    },
    {
      "nct_id": "NCT06098755",
      "title": "The Sequestration of Holistic Stress Management Techniques for Adults",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress, Job",
        "PTSD",
        "Hypervigilance",
        "Hyperthyroidism",
        "Migraine",
        "Migraine With Aura",
        "Immunodeficiency",
        "Sickle Cell Trait",
        "Sickle Cell Disease",
        "Anemia, Sickle Cell",
        "Anemia",
        "Fatigue",
        "Anxiety",
        "Depression",
        "Flat Feet",
        "Lordosis",
        "TBI (Traumatic Brain Injury)",
        "Rheumatoid Arthritis",
        "Arthritis",
        "Masturbation",
        "Priapism",
        "Erectile Dysfunction",
        "Flight Reaction",
        "Hypertension",
        "Sexual Arousal Disorder",
        "Hemorrhoids",
        "Fibroid"
      ],
      "interventions": [
        {
          "name": "Holistic Medicine (HM)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Goddess Zena I. Jones",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2026-01-26",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "Anchorage, Alaska",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06098755"
    },
    {
      "nct_id": "NCT02041585",
      "title": "Discharge Functional Status and Rehospitalization in the Elderly",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Social Isolation",
        "Depression",
        "Anxiety",
        "Debility"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2012-10",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2023-03-06",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02041585"
    },
    {
      "nct_id": "NCT01453452",
      "title": "S1008: Exercise, Diet, & Counseling in Improving Weight Loss in Overweight Female Breast or Colorectal Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety Disorder",
        "Breast Cancer",
        "Cognitive/Functional Effects",
        "Colorectal Cancer",
        "Depression",
        "Fatigue",
        "Pain",
        "Psychosocial Effects of Cancer and Its Treatment",
        "Weight Changes"
      ],
      "interventions": [
        {
          "name": "behavioral dietary intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "exercise intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "counseling intervention",
          "type": "OTHER"
        },
        {
          "name": "quality-of-life assessment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "SWOG Cancer Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "120 Years",
        "sex": "FEMALE",
        "summary": "Up to 120 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2012-03",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 58,
      "location_summary": "Tucson, Arizona • Antioch, California • Fremont, California + 45 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Antioch",
          "state": "California"
        },
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01453452"
    },
    {
      "nct_id": "NCT05783232",
      "title": "Radicle Health1: A Study of Health and Wellness Formulations and Their Effects on Overall Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep",
        "Pain",
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Placebo Control Form 1 Capsules",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Health Active Study Product 1.1 Capsules",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Health Active Study Product 1.2 Capsules",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Health Active Study Product 1.3 Capsules",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Radicle Science",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "105 Years",
        "sex": "ALL",
        "summary": "21 Years to 105 Years"
      },
      "enrollment_count": 1494,
      "start_date": "2023-03-21",
      "completion_date": "2023-10-27",
      "has_results": false,
      "last_update_posted_date": "2023-11-22",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "Del Mar, California",
      "locations": [
        {
          "city": "Del Mar",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05783232"
    },
    {
      "nct_id": "NCT03129204",
      "title": "Sensation Awareness Focused Training for Spouses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post Intensive Care Syndrome",
        "Anxiety",
        "Depression",
        "Posttraumatic Stress Disorder",
        "Sleep Deprivation"
      ],
      "interventions": [
        {
          "name": "SAF-T",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2017-09-03",
      "completion_date": "2018-02-26",
      "has_results": false,
      "last_update_posted_date": "2020-07-07",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03129204"
    },
    {
      "nct_id": "NCT05779761",
      "title": "Brief Interventions for Coping with Distress",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Distress, Emotional",
        "Emotional Dysfunction",
        "Anxiety",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Online, Self-Directed Attention Skills Training with Coaching Support",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Online, Self-Directed Health & Wellness Education Training with Coaching Support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Teachers College, Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 180,
      "start_date": "2023-05-12",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-11-21",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05779761"
    },
    {
      "nct_id": "NCT01253044",
      "title": "Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Distress",
        "Anxiety",
        "Depression",
        "Postconcussive Symptoms"
      ],
      "interventions": [
        {
          "name": "Acceptance and Commitment Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Present Centered Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Veterans Medical Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2010-11",
      "completion_date": "2013-08",
      "has_results": true,
      "last_update_posted_date": "2015-10-19",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 6,
      "location_summary": "La Jolla, California • Washington D.C., District of Columbia • Augusta, Maine + 3 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Augusta",
          "state": "Maine"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01253044"
    },
    {
      "nct_id": "NCT05685511",
      "title": "Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Older Adults",
        "Anxiety",
        "Depression",
        "Major Surgical Resection of a Thoracic Malignancy",
        "Major Surgical Resection of an Abdominal Malignancy"
      ],
      "interventions": [
        {
          "name": "Behavioral Activation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Medication Optimization",
          "type": "OTHER"
        },
        {
          "name": "Usual care resources",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 105,
      "start_date": "2023-03-10",
      "completion_date": "2024-07-12",
      "has_results": true,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-10-25T12:54:18.578Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05685511"
    }
  ]
}