{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Syndesmotic+Injuries",
    "query": {
      "condition": "Syndesmotic Injuries"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:26:26.945Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05445960",
      "title": "Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Ankle Fracture - Lateral Malleolus",
        "Ankle Fracture, Bimalleolar",
        "Ankle Fracture, Trimalleolar",
        "Ankle Fracture - Medial Malleolus",
        "Maisonneuve's Fracture",
        "Syndesmotic Injuries",
        "Fibula Fracture"
      ],
      "interventions": [
        {
          "name": "Tourniquet",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 390,
      "start_date": "2021-08-17",
      "completion_date": "2027-03-17",
      "has_results": false,
      "last_update_posted_date": "2025-03-24",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05445960"
    },
    {
      "nct_id": "NCT05729542",
      "title": "Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Injuries",
        "Syndesmotic Injuries",
        "Ankle Fractures"
      ],
      "interventions": [
        {
          "name": "Arthrex Tightrope",
          "type": "DEVICE"
        },
        {
          "name": "Synthes Fibulink",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2021-11-18",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-10",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05729542"
    },
    {
      "nct_id": "NCT05190874",
      "title": "Grappler Interference Screw Post-Market Collection of Patient Reported Outcome Measures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ankle Injuries",
        "Syndesmotic Injuries",
        "Ankle Inversion Sprain",
        "Deltoid Ankle Sprain",
        "Achilles Tendon Rupture",
        "Flexor Hallucis Longus on the Left",
        "Flexor Hallucis Longus on the Right",
        "Flexor Digitorum Longus on the Left",
        "Flexor Digitorum Longus on the Right",
        "Ankle Sprains"
      ],
      "interventions": [
        {
          "name": "Grappler Interference Screw System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Paragon 28",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 19,
      "start_date": "2022-01-14",
      "completion_date": "2022-04-06",
      "has_results": false,
      "last_update_posted_date": "2022-04-07",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Worthington, Ohio",
      "locations": [
        {
          "city": "Worthington",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05190874"
    },
    {
      "nct_id": "NCT06085586",
      "title": "Fibulink Syndesmosis Repair System With Early Full-Weight Bearing",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Bimalleolar Fractures",
        "Syndesmotic Injuries",
        "Bimalleolar Equivalent Fracture",
        "Maisonneuve Fracture",
        "Trimalleolar Fractures",
        "Ankle Dislocation"
      ],
      "interventions": [
        {
          "name": "Early Weight Bearing",
          "type": "OTHER"
        },
        {
          "name": "Normal Weight Bearing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Maimonides Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2023-07-13",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06085586"
    },
    {
      "nct_id": "NCT03163017",
      "title": "Assessment of Ability of 3D Fluorscopy in Aiding Accurate Syndesmotic Reduction Following Traumatic Ankle Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Displaced Ankle Fractures"
      ],
      "interventions": [
        {
          "name": "2D Fluoroscopy",
          "type": "DEVICE"
        },
        {
          "name": "3D Fluoroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2017-03-01",
      "completion_date": "2018-09-11",
      "has_results": true,
      "last_update_posted_date": "2019-09-12",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03163017"
    },
    {
      "nct_id": "NCT05626036",
      "title": "Randomized Controlled Trial Comparing Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Syndesmotic Injuries"
      ],
      "interventions": [
        {
          "name": "Arthrex Tightrope",
          "type": "DEVICE"
        },
        {
          "name": "Synthes Fibulink",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2022-12-01",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2024-05-06",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05626036"
    },
    {
      "nct_id": "NCT04933045",
      "title": "Treatment of Syndesmotic Disruption With Anatomic Distal Tibiofibular Ligament Augmentation",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Syndesmotic Injuries"
      ],
      "interventions": [
        {
          "name": "Arthrex InternalBrace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "St. Clair Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "105 Years",
        "sex": "ALL",
        "summary": "18 Years to 105 Years"
      },
      "enrollment_count": 32,
      "start_date": "2021-07-01",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-06-21",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Saint Clair Shores, Michigan",
      "locations": [
        {
          "city": "Saint Clair Shores",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04933045"
    },
    {
      "nct_id": "NCT02892500",
      "title": "Investigation of Corticosteroid Versus Placebo Injection in Patients With Syndesmotic Ligament Injury or High Ankle Sprain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ankle Injuries"
      ],
      "interventions": [
        {
          "name": "bupivacaine hydrochloride and betamethasone sodium phosphate",
          "type": "DRUG"
        },
        {
          "name": "bupivacaine hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sanford Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2016-04",
      "completion_date": "2016-09-21",
      "has_results": true,
      "last_update_posted_date": "2024-02-13",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Fargo, North Dakota",
      "locations": [
        {
          "city": "Fargo",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02892500"
    },
    {
      "nct_id": "NCT04893824",
      "title": "Grappler® Interference Screw Post-Market Clinical Follow-Up Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ankle Injuries",
        "Syndesmotic Injuries",
        "Ankle Inversion Sprain",
        "Deltoid Ankle Sprain",
        "Achilles Tendon Rupture",
        "Flexor Hallucis Longus on the Left",
        "Flexor Digitorum Longus on the Left",
        "Ankle Sprains",
        "Flexor Hallucis Longus on the Right",
        "Flexor Digitorum Longus on the Right"
      ],
      "interventions": [
        {
          "name": "Grappler® Interference Screw System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Paragon 28",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 50,
      "start_date": "2021-04-19",
      "completion_date": "2022-03-25",
      "has_results": false,
      "last_update_posted_date": "2023-11-15",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Worthington, Ohio",
      "locations": [
        {
          "city": "Worthington",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04893824"
    },
    {
      "nct_id": "NCT05062265",
      "title": "Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Syndesmotic Injuries",
        "Ligament Rupture",
        "Bimalleolar Fractures",
        "Trimalleolar Fractures"
      ],
      "interventions": [
        {
          "name": "Tight rope fixation",
          "type": "DEVICE"
        },
        {
          "name": "Tight rope fixation with an anterior inferior tibiofibular ligament (AITFL) repair augmentation with an internal brace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vann Virginia Center for Orthopaedics dba Atlantic Orthopaedic Specialists",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 23,
      "start_date": "2022-01-31",
      "completion_date": "2023-12-31",
      "has_results": true,
      "last_update_posted_date": "2025-02-19",
      "last_synced_at": "2026-05-22T05:26:26.945Z",
      "location_count": 1,
      "location_summary": "Virginia Beach, Virginia",
      "locations": [
        {
          "city": "Virginia Beach",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05062265"
    }
  ]
}