{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Synkinesis",
    "query": {
      "condition": "Synkinesis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:18:06.046Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03059420",
      "title": "Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Fibrosis of Extraocular Muscles",
        "Duane Retraction Syndrome",
        "Duane Radial Ray Syndrome",
        "Mobius Syndrome",
        "Brown Syndrome",
        "Marcus Gunn Syndrome",
        "Strabismus Congenital",
        "Horizontal Gaze Palsy",
        "Horizontal Gaze Palsy With Progressive Scoliosis",
        "Facial Palsy",
        "Facial Paresis, Hereditary, Congenital",
        "Third Nerve Palsy",
        "Fourth Nerve Palsy",
        "Sixth Nerve Palsy",
        "Synkinesis",
        "Ocular Motility Disorders",
        "Levator-Medial Rectus Synkinesis",
        "Athabaskan Brainstem Dysgenesis",
        "Tongue Paralysis",
        "Ninth Nerve Disorder",
        "Fifth Nerve Palsy",
        "Seventh Nerve Palsy",
        "Eleventh Nerve Disorder",
        "Twelfth Nerve Disorder",
        "Vagus Nerve Paralysis",
        "Moebius Sequence"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Day and older"
      },
      "enrollment_count": 20000,
      "start_date": "2004-02-01",
      "completion_date": "2030-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-11",
      "last_synced_at": "2026-05-22T05:18:06.046Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03059420"
    },
    {
      "nct_id": "NCT05945615",
      "title": "Oxymetazoline Drops for Acquired Blepharoptosis From Synkinesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Blepharoptosis",
        "Synkinesis",
        "Hyperkinesis",
        "Facial Paralysis"
      ],
      "interventions": [
        {
          "name": "Oxymetazoline 0.1% (Pf) Oph Soln Ud",
          "type": "DRUG"
        },
        {
          "name": "Preservative free lubricating drops",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 36,
      "start_date": "2024-01-11",
      "completion_date": "2026-01-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-05-22T05:18:06.046Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05945615"
    },
    {
      "nct_id": "NCT07127016",
      "title": "Mindfulness in Nonflaccid Facial Paralysis",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Facial Paralysis"
      ],
      "interventions": [
        {
          "name": "Mindfulness Sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No Mindfulness Sessions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2026-05",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-05-22T05:18:06.046Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07127016"
    },
    {
      "nct_id": "NCT04148872",
      "title": "Mixed Methods Investigation of Chronic Facial Paralysis in Individuals With Synkinesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Synkinesis"
      ],
      "interventions": [
        {
          "name": "Neuromuscular Retraining Therapy (4 months)",
          "type": "OTHER"
        },
        {
          "name": "Chemodenervation (4 months)",
          "type": "DRUG"
        },
        {
          "name": "Neuromuscular Retraining + Chemodenervation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 15,
      "start_date": "2019-10-24",
      "completion_date": "2021-08-24",
      "has_results": true,
      "last_update_posted_date": "2022-09-29",
      "last_synced_at": "2026-05-22T05:18:06.046Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04148872"
    }
  ]
}