{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Systemic+Exertion+Intolerance+Disease+%28SEID%29&page=2",
    "query": {
      "condition": "Systemic Exertion Intolerance Disease (SEID)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Systemic+Exertion+Intolerance+Disease+%28SEID%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T20:17:39.208Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00540254",
      "title": "Behavioral Insomnia Therapy With Chronic Fatigue Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome",
        "Behavioral Therapy Targeted to Sleep Problems"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care for Chronic Fatigue Syndrome (Active Control Group)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 24,
      "start_date": "2007-09",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2013-03-01",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00540254"
    },
    {
      "nct_id": "NCT01893619",
      "title": "Observational Research on Use of Immunoprop Supplement in Chronic Fatigue Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "New York CFS Association",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 100,
      "start_date": "2013-06",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2013-07-25",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01893619"
    },
    {
      "nct_id": "NCT00580619",
      "title": "Autonomic Nervous System and Chronic Fatigue Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome",
        "Orthostatic Intolerance",
        "Postural Tachycardia Syndrome"
      ],
      "interventions": [
        {
          "name": "Autonomic Function Testing",
          "type": "OTHER"
        },
        {
          "name": "Saline infusions",
          "type": "OTHER"
        },
        {
          "name": "L-NMMA trimethaphan",
          "type": "DRUG"
        },
        {
          "name": "methyldopa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 170,
      "start_date": "2007-04",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2017-01-18",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00580619"
    },
    {
      "nct_id": "NCT00252629",
      "title": "Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apnea, Sleep",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Nasal CPAP treatment during sleep",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "32 Years",
        "maximum_age": "52 Years",
        "sex": "MALE",
        "summary": "32 Years to 52 Years · Male only"
      },
      "enrollment_count": 29,
      "start_date": "2005-11",
      "completion_date": "2010-11",
      "has_results": true,
      "last_update_posted_date": "2014-12-11",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "Northport, New York",
      "locations": [
        {
          "city": "Northport",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00252629"
    },
    {
      "nct_id": "NCT04542161",
      "title": "Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome",
        "Myalgic Encephalomyelitis"
      ],
      "interventions": [
        {
          "name": "NAC 900mg/day",
          "type": "DRUG"
        },
        {
          "name": "NAC 3600mg/day",
          "type": "DRUG"
        },
        {
          "name": "NAC 0mg/day (Placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 95,
      "start_date": "2020-09-01",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04542161"
    },
    {
      "nct_id": "NCT00997451",
      "title": "Fatigue Self-Management in Primary Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Medically Unexplained Chronic Fatigue",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Cognitive-behavioral self-management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Symptom monitoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 107,
      "start_date": "2009-02",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2012-10-01",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00997451"
    },
    {
      "nct_id": "NCT02669212",
      "title": "Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Cardiopulmonary Exercise Test (CPET)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 52,
      "start_date": "2016-10-10",
      "completion_date": "2022-01-11",
      "has_results": true,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02669212"
    },
    {
      "nct_id": "NCT05608629",
      "title": "Vagus Nerve Stimulation as Treatment for Long Covid",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Long COVID",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Non-Invasive Vagus Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "Up to 70 Years"
      },
      "enrollment_count": 17,
      "start_date": "2022-06-06",
      "completion_date": "2022-12-05",
      "has_results": true,
      "last_update_posted_date": "2024-01-08",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05608629"
    },
    {
      "nct_id": "NCT05664711",
      "title": "Effect of Stellate Ganglion Block on ME/CFS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Encephalomyelitis, Myalgic",
        "Chronic Fatigue Syndrome",
        "Chronic Fatigue Disorder",
        "Chronic Fatigue and Immune Dysfunction Syndrome",
        "Myalgic Encephalomyelitis",
        "Postviral Fatigue Syndrome",
        "Systemic Exertion Intolerance Disease",
        "Infectious Mononucleosis-Like Syndrome, Chronic",
        "Chronic Fatigue-Fibromyalgia Syndrome"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Neuroversion, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2023-03-15",
      "completion_date": "2024-01-15",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "Anchorage, Alaska",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05664711"
    },
    {
      "nct_id": "NCT01650636",
      "title": "Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Patient-Partner Videotelephone-delivered Health Information (PP-T-HI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient-Partner Videotelephone-delivered Cognitive Behavioral Stress Management intervention (PP-T-CBSM)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 300,
      "start_date": "2010-10",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2018-12-10",
      "last_synced_at": "2026-07-23T20:17:39.208Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01650636"
    }
  ]
}