{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=TBI+Traumatic+Brain+Injury",
    "query": {
      "condition": "TBI Traumatic Brain Injury"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 1249,
    "total_pages": 125,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=TBI+Traumatic+Brain+Injury&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T03:18:37.168Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02974959",
      "title": "Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Traumatic Brain Injury",
        "Acute Brain Injuries"
      ],
      "interventions": [
        {
          "name": "gammaCore active device",
          "type": "DEVICE"
        },
        {
          "name": "gammaCore sham device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CentraCare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 14,
      "start_date": "2016-10",
      "completion_date": "2020-11",
      "has_results": false,
      "last_update_posted_date": "2021-02-04",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02974959"
    },
    {
      "nct_id": "NCT04972786",
      "title": "Noninvasive Modulation of Motivational Brain Regions in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Repetitive Transcranial Magnetic Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 21,
      "start_date": "2021-08-01",
      "completion_date": "2023-06-21",
      "has_results": true,
      "last_update_posted_date": "2024-07-16",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04972786"
    },
    {
      "nct_id": "NCT06073886",
      "title": "Personalized Brain Stimulation to Treat Chronic Concussive Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post-Concussion Syndrome",
        "Concussion, Brain",
        "Mild Traumatic Brain Injury",
        "Head Injury",
        "Headache",
        "Dizziness",
        "Cognitive Symptom",
        "Dysautonomia",
        "Anxiety",
        "Irritability; Syndrome",
        "Depression",
        "Post-traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Active cTBS",
          "type": "DEVICE"
        },
        {
          "name": "Inactive/Sham cTBS",
          "type": "DEVICE"
        },
        {
          "name": "Imaginal exposure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 75,
      "start_date": "2024-03-06",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Westwood, Los Angeles, California",
      "locations": [
        {
          "city": "Westwood, Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06073886"
    },
    {
      "nct_id": "NCT03307070",
      "title": "Adapted Cognitive Behavioral Treatment for Depression in Patients With Moderate to Severe Traumatic Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for individuals with TBI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Waitlist Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2017-09-23",
      "completion_date": "2022-11-28",
      "has_results": false,
      "last_update_posted_date": "2023-04-10",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03307070"
    },
    {
      "nct_id": "NCT02368366",
      "title": "Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tbi",
        "Intracranial Edema",
        "Brain Edema",
        "Craniocerebral Trauma",
        "Head Injury",
        "Brain Hemorrhage, Traumatic",
        "Subdural Hematoma",
        "Brain Concussion",
        "Head Injuries, Closed",
        "Epidural Hematoma",
        "Cortical Contusion",
        "Wounds and Injuries",
        "Disorders of Environmental Origin",
        "Trauma, Nervous System",
        "Brain Injuries"
      ],
      "interventions": [
        {
          "name": "Therapist Guided Face to Face Family Problem Solving",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Therapist Guided Online Family Problem Solving",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-Guided Online Family Problem Solving",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "14 Years to 19 Years"
      },
      "enrollment_count": 151,
      "start_date": "2014-11",
      "completion_date": "2017-11",
      "has_results": false,
      "last_update_posted_date": "2018-01-29",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 5,
      "location_summary": "Denver, Colorado • Cincinnati, Ohio • Cleveland, Ohio + 1 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02368366"
    },
    {
      "nct_id": "NCT02714192",
      "title": "Safety Study for Adolescents With Concussion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Injury",
        "Concussion"
      ],
      "interventions": [
        {
          "name": "Exercise stress test (BCTT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "14 Years to 19 Years"
      },
      "enrollment_count": 54,
      "start_date": "2013-03",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2016-03-21",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02714192"
    },
    {
      "nct_id": "NCT03674398",
      "title": "Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Concussion Syndrome",
        "Post-Traumatic Headache",
        "Post-Concussive Syndrome, Chronic",
        "Head Injury",
        "MTBI - Mild Traumatic Brain Injury",
        "Acquired Brain Injury",
        "Closed Head Injury"
      ],
      "interventions": [
        {
          "name": "Exercise+CT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2018-10-01",
      "completion_date": "2019-05-03",
      "has_results": false,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03674398"
    },
    {
      "nct_id": "NCT02352441",
      "title": "Cognitive Rehabilitation:ACTION Training for Soldiers With Executive Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Implementation Intentions(II)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Allina Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2016-06",
      "completion_date": "2017-09-29",
      "has_results": false,
      "last_update_posted_date": "2018-01-11",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Fort Campbell North, Kentucky",
      "locations": [
        {
          "city": "Fort Campbell North",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02352441"
    },
    {
      "nct_id": "NCT00795366",
      "title": "Vasopressin Versus Catecholamines for Cerebral Perfusion Pressure Control in Brain Injured Trauma Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "arginine vasopressin",
          "type": "DRUG"
        },
        {
          "name": "Standard catecholamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2008-09",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2014-12-12",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00795366"
    },
    {
      "nct_id": "NCT03221751",
      "title": "Prazosin and Cerebrospinal Fluid (CSF) Biomarkers in Mild Traumatic Brain Injury (mTBI)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dementia"
      ],
      "interventions": [
        {
          "name": "prazosin hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2016-12-01",
      "completion_date": "2023-12-05",
      "has_results": true,
      "last_update_posted_date": "2024-02-26",
      "last_synced_at": "2026-06-26T03:18:37.168Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03221751"
    }
  ]
}