{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=TRIO",
    "query": {
      "condition": "TRIO"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=TRIO&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:29:57.616Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04884659",
      "title": "Time-Restricted Feeding",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Inflammatory Markers",
        "Glycemic Variation",
        "Time Restricted Feeding",
        "Ketosis"
      ],
      "interventions": [
        {
          "name": "Time restricted feeding arm",
          "type": "OTHER"
        },
        {
          "name": "usual feeding pattern arm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-06-10",
      "completion_date": "2022-08-15",
      "has_results": false,
      "last_update_posted_date": "2022-08-24",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04884659"
    },
    {
      "nct_id": "NCT01728363",
      "title": "Pharmacokinetics (PK) of Antistaphylococcal Antibiotics in Infants (NICHD-2012-02-Staph Trio)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Systemic Infection"
      ],
      "interventions": [
        {
          "name": "Antibiotic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Phillip Brian Smith",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Days",
        "maximum_age": "32 Weeks",
        "sex": "ALL",
        "summary": "14 Days to 32 Weeks"
      },
      "enrollment_count": 63,
      "start_date": "2013-01",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 10,
      "location_summary": "Gainesville, Florida • Jacksonville, Florida • Atlanta, Georgia + 7 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Wichita",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01728363"
    },
    {
      "nct_id": "NCT01444859",
      "title": "Trenev Trio®/Healthy Trinity® for Recurrent Gastrointestinal Symptoms",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Recurrent Gastrointestinal Symptoms"
      ],
      "interventions": [
        {
          "name": "Trenev Trio®/Healthy Trinity®",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Sprim Advanced Life Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2012-02",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2012-10-24",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 5,
      "location_summary": "Los Angeles, California • San Francisco, California • West Lawn, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "West Lawn",
          "state": "Pennsylvania"
        },
        {
          "city": "Carrollton",
          "state": "Texas"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01444859"
    },
    {
      "nct_id": "NCT03672773",
      "title": "Talazoparib and Low-Dose Temozolomide in Treating Participants With Relapsed or Refractory Extensive-Stage Small Cell Lung Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Recurrent Extensive Stage Small Cell Lung Carcinoma",
        "Refractory Extensive Stage Small Cell Lung Carcinoma"
      ],
      "interventions": [
        {
          "name": "Talazoparib",
          "type": "DRUG"
        },
        {
          "name": "Temozolomide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jonsson Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2018-10-31",
      "completion_date": "2027-10-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 6,
      "location_summary": "Bakersfield, California • Fullerton, California • Los Angeles, California + 3 more",
      "locations": [
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03672773"
    },
    {
      "nct_id": "NCT04470024",
      "title": "Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cancer of the Head and Neck"
      ],
      "interventions": [
        {
          "name": "INCAGN01876",
          "type": "DRUG"
        },
        {
          "name": "INCMGA00012",
          "type": "DRUG"
        },
        {
          "name": "DPV-001",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "Providence Health & Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2021-08-05",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04470024"
    },
    {
      "nct_id": "NCT05480215",
      "title": "Symptomatic Relief of Action Tremor With Cala Trio Using Trio+ Bands",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Essential Tremor",
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Cala Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cala Health, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2021-10-07",
      "completion_date": "2021-12-16",
      "has_results": false,
      "last_update_posted_date": "2022-07-29",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 1,
      "location_summary": "San Mateo, California",
      "locations": [
        {
          "city": "San Mateo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05480215"
    },
    {
      "nct_id": "NCT01268618",
      "title": "Trenev Trio/Healthy Trinity for Symptoms of Diarrhea-predominant Irritable Bowel Syndrome (IBS) and Functional Dyspepsia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "IBS-D and Functional Dyspepsia"
      ],
      "interventions": [
        {
          "name": "Probiotic",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Sprim Advanced Life Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 120,
      "start_date": "2011-01",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2011-07-21",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 2,
      "location_summary": "Duluth, Georgia • Norfolk, Virginia",
      "locations": [
        {
          "city": "Duluth",
          "state": "Georgia"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01268618"
    },
    {
      "nct_id": "NCT05540626",
      "title": "RWE Study Utilizing the Cala Trio Device in Patients With Essential Tremor",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Essential Tremor"
      ],
      "interventions": [
        {
          "name": "Cala Trio",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cala Health, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 276,
      "start_date": "2021-04-08",
      "completion_date": "2024-03-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-07",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 1,
      "location_summary": "San Mateo, California",
      "locations": [
        {
          "city": "San Mateo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05540626"
    },
    {
      "nct_id": "NCT04599751",
      "title": "The Trio Laser Module for Hair Removal Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hair Removal Treatment"
      ],
      "interventions": [
        {
          "name": "Hair removal treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alma Lasers",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 37,
      "start_date": "2020-10-07",
      "completion_date": "2021-11-16",
      "has_results": false,
      "last_update_posted_date": "2021-11-17",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 2,
      "location_summary": "Hollywood, Florida • Nashville, Tennessee",
      "locations": [
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04599751"
    },
    {
      "nct_id": "NCT01238250",
      "title": "Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "16P11.2 Deletion Syndrome",
        "16p11.2 Duplications",
        "1Q21.1 Deletion",
        "1Q21.1 Microduplication Syndrome (Disorder)",
        "ACTL6B",
        "ADNP",
        "AHDC1",
        "ANK2",
        "ANKRD11",
        "ARID1B",
        "ASH1L",
        "BCL11A",
        "CHAMP1",
        "CHD2",
        "CHD8",
        "CSNK2A1",
        "CTBP1",
        "CTNNB1 Gene Mutation",
        "CUL3",
        "DDX3X",
        "DNMT3A",
        "DSCAM",
        "DYRK1A",
        "FOXP1",
        "GRIN2A",
        "GRIN2B",
        "HIVEP2-Related Intellectual Disability",
        "HNRNPH2",
        "KATNAL2",
        "KDM5B",
        "KDM6B",
        "KMT2C Gene Mutation",
        "KMT2E",
        "KMT5B",
        "MBD5",
        "MED13L",
        "PACS1",
        "PPP2R5D-Related Intellectual Disability",
        "PTCHD1",
        "REST",
        "SCN2A Encephalopathy",
        "SETBP1 Gene Mutation",
        "SETD5",
        "SMARCA4 Gene Mutation",
        "SMARCC2",
        "STXBP1 Encephalopathy With Epilepsy",
        "SYNGAP1-Related Intellectual Disability",
        "TBR1",
        "ARHGEF9",
        "HNRNPU",
        "PPP3CA",
        "PPP2R1A",
        "SLC6A1",
        "2p16.3 Deletions",
        "5q35 Deletions",
        "5q35 Duplications",
        "7q11.23 Duplications",
        "15Q13.3 Deletion Syndrome",
        "16p11.2 Triplications",
        "16P12.2 Microdeletion",
        "16P13.11 Microdeletion Syndrome (Disorder)",
        "17Q12 Microdeletion Syndrome (Disorder)",
        "17Q12 Duplication Syndrome",
        "17Q21.31 Deletion Syndrome",
        "17q21.3 Duplications",
        "ACTB",
        "ADSL",
        "AFF2",
        "ALDH5A1",
        "ANK3",
        "ARX",
        "ATRX Gene Mutation",
        "AUTS2 Syndrome",
        "BCKDK",
        "BRSK2",
        "CACNA1C",
        "CAPRIN1",
        "CASK",
        "CASZ1",
        "CHD3",
        "CIC",
        "CNOT3",
        "CREBBP Gene Mutation",
        "CSDE1",
        "CTCF",
        "DEAF1",
        "DHCR7",
        "DLG4",
        "EBF3",
        "EHMT1",
        "EP300 Gene Mutation",
        "GIGYF1",
        "GRIN1",
        "GRIN2D",
        "IQSEC2-Related Syndromic Intellectual Disability",
        "IRF2BPL",
        "KANSL1",
        "KCNB1",
        "KDM3B",
        "NEXMIF",
        "KMT2A",
        "MBOAT7",
        "MEIS2",
        "MYT1L",
        "NAA15",
        "NBEA",
        "NCKAP1",
        "NIPBL",
        "NLGN2",
        "NLGN3",
        "NLGN4X",
        "NR4A2",
        "NRXN1",
        "NRXN2",
        "NSD1 Gene Mutation",
        "PHF21A",
        "PHF3",
        "PHIP",
        "POMGNT1",
        "PSMD12",
        "RELN",
        "RERE",
        "RFX3",
        "RIMS1",
        "RORB",
        "SCN1A",
        "SETD2 Gene Mutation",
        "SHANK2",
        "SIN3A",
        "SLC9A6",
        "SON",
        "SOX5",
        "SPAST",
        "SRCAP",
        "TAOK1",
        "TANC2",
        "TCF20",
        "TLK2",
        "TRIO",
        "TRIP12",
        "UPF3B",
        "USP9X",
        "VPS13B",
        "WAC",
        "WDFY3",
        "ZBTB20",
        "ZNF292",
        "ZNF462",
        "2Q37 Deletion Syndrome",
        "9q34 Duplications",
        "15q15 Deletions",
        "15Q24 Deletion",
        "NR3C2",
        "SYNCRIP",
        "2q34 Duplication",
        "2q37.3 Deletion",
        "6q16 Deletion",
        "15q11.2 BP1-BP2 Deletion",
        "16p13.3 Deletion",
        "17Q11.2 Microduplication Syndrome (Disorder)",
        "17p13.3",
        "Xq28 Duplication",
        "CLCN4",
        "CSNK2B",
        "DYNC1H1",
        "EIF3F",
        "GNB1",
        "MED13",
        "MEF2C",
        "RALGAPB",
        "SCN1B",
        "YY1",
        "Xp11.22 Duplication",
        "PACS2",
        "MAOA",
        "MAOB",
        "HNRNPC",
        "HNRNPD",
        "HNRNPK",
        "HNRNPR",
        "HNRNPUL2",
        "5P Deletion Syndrome",
        "TCF7L2 Gene Mutation",
        "HECW2"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Simons Searchlight",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100000,
      "start_date": "2010-10",
      "completion_date": "2050-10",
      "has_results": false,
      "last_update_posted_date": "2025-06-06",
      "last_synced_at": "2026-05-22T04:29:57.616Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Lewisburg, Pennsylvania",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Lewisburg",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01238250"
    }
  ]
}