{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Takotsubo+Syndrome",
    "query": {
      "condition": "Takotsubo Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Takotsubo+Syndrome&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:45:00.723Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00586183",
      "title": "Cardiac Sympathetic Activity in Patients With the Apical Ballooning Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apical Ballooning Syndrome"
      ],
      "interventions": [
        {
          "name": "PET scan",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2006-03",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2008-01-04",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00586183"
    },
    {
      "nct_id": "NCT03324529",
      "title": "Autonomic Modulation in Takotsubo Syndrome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Takotsubo Syndrome"
      ],
      "interventions": [
        {
          "name": "Tako Breath",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2021-10-01",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03324529"
    },
    {
      "nct_id": "NCT01048125",
      "title": "Characterization of Sympathetic Nerve Activity in Stress Cardiomyopathy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "Sympathetic Nerve Activity",
          "type": "DEVICE"
        },
        {
          "name": "Mental Stress Test (Color Word Test)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The Modified Oxford Technique for Baroreflex Sensitivity",
          "type": "DRUG"
        },
        {
          "name": "Cold Pressor Test",
          "type": "OTHER"
        },
        {
          "name": "Echocardiographic evaluation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 2,
      "start_date": "2009-08",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2016-11-23",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01048125"
    },
    {
      "nct_id": "NCT04325321",
      "title": "The Broken Heart Study II (BHS-II)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Takotsubo Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "Stress reactivity test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Miriam Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2020-09-02",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04325321"
    },
    {
      "nct_id": "NCT03801694",
      "title": "Predicting the Development of Myocardial Depression in Acute Neurological Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myocardial Depression",
        "Takotsubo Syndrome",
        "Subarachnoid Hemorrhage",
        "Acute Ischemic Stroke"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "50 Years and older · Female only"
      },
      "enrollment_count": 4,
      "start_date": "2018-12-03",
      "completion_date": "2024-04-14",
      "has_results": false,
      "last_update_posted_date": "2024-04-16",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03801694"
    },
    {
      "nct_id": "NCT01432626",
      "title": "Pathogenesis of Stress-Induced Cardiomyopathy by I-123 MIBG",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Induced Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "I-123 radiolabeled metaiodobenzylguanidine cardiac imaging",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2011-09",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2016-03-22",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01432626"
    },
    {
      "nct_id": "NCT05977049",
      "title": "Psychosocial Support for Patients With Takotsubo Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Takotsubo Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "Takotsubo Support Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2024-04-17",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05977049"
    },
    {
      "nct_id": "NCT03910569",
      "title": "The Cedars-Sinai Smidt Heart Institute Takotsubo Registry & Proteomic Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Takotsubo Cardiomyopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2019-02-01",
      "completion_date": "2029-02",
      "has_results": false,
      "last_update_posted_date": "2025-08-20",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03910569"
    },
    {
      "nct_id": "NCT00975559",
      "title": "The Relationship Between the Response to Mental Stress and Vascular Endothelial Function",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Endothelial Dysfunction",
        "Apical Ballooning Syndrome",
        "Myocardial Infarction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 190,
      "start_date": "2003-09",
      "completion_date": "2011-04",
      "has_results": false,
      "last_update_posted_date": "2012-04-26",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00975559"
    },
    {
      "nct_id": "NCT01885975",
      "title": "Personality Profile of Patients With Apical Ballooning Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Apical Ballooning Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2013-07",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2015-02-16",
      "last_synced_at": "2026-05-22T09:45:00.723Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01885975"
    }
  ]
}