{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Telomere+Biology+Disorders",
    "query": {
      "condition": "Telomere Biology Disorders"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:48:28.203Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04211714",
      "title": "Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Telomere Shortening",
        "Bone Marrow Failure"
      ],
      "interventions": [
        {
          "name": "EXG34217",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Elixirgen Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2021-04-08",
      "completion_date": "2027-10-08",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04211714"
    },
    {
      "nct_id": "NCT06817590",
      "title": "Nucleoside Therapy in Patients With Telomere Biology Disorders",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Telomere Biology Disorders",
        "Dyskeratosis Congenita",
        "Revesz Syndrome",
        "Hoyeraal Hreidarsson Syndrome",
        "Telomere Biology Disorders With Bone Marrow Failure",
        "Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder)",
        "Pulmonary Fibrosis, Familial (Telomere Biology Disorder)"
      ],
      "interventions": [
        {
          "name": "deoxycytidine",
          "type": "DRUG"
        },
        {
          "name": "deoxythymidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Suneet Agarwal",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "1 Year to 70 Years"
      },
      "enrollment_count": 36,
      "start_date": "2025-09-29",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06817590"
    },
    {
      "nct_id": "NCT05012111",
      "title": "Natural History of Acquired and Inherited Bone Marrow Failure Syndromes",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Severe Aplastic Anemia",
        "Telomere Biology Disorders",
        "Inherited Bone Marrow Failure Syndromes"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "2 Years to 99 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2021-10-25",
      "completion_date": "2041-02-04",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05012111"
    },
    {
      "nct_id": "NCT04232085",
      "title": "Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Primary Immune Deficiency Disorder",
        "Immune Deficiency Disease",
        "Bone Marrow Failure",
        "Short Telomere Length",
        "Fanconi Anemia",
        "Non Fanconi DNA-DSB Repair Disorder",
        "Hoyeraal-Hreidarsson Syndrome",
        "Dyskeratosis Congenita",
        "Telomere Biology Disorder",
        "Short Telomere Syndrome"
      ],
      "interventions": [
        {
          "name": "Alemtuzumab",
          "type": "DRUG"
        },
        {
          "name": "Fludarabine",
          "type": "DRUG"
        },
        {
          "name": "Melphalan",
          "type": "DRUG"
        },
        {
          "name": "Low Dose Total Body Irradiation",
          "type": "RADIATION"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "Tacrolimus",
          "type": "DRUG"
        },
        {
          "name": "Mycophenolate Mofetil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "RADIATION"
      ],
      "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Months",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "4 Months to 50 Years"
      },
      "enrollment_count": 27,
      "start_date": "2020-02-12",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-28",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04232085"
    },
    {
      "nct_id": "NCT03579875",
      "title": "Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fanconi Anemia",
        "Severe Aplastic Anemia",
        "Myelodysplastic Syndromes",
        "T Cell Receptor Alpha/Beta Depletion",
        "Telomere Biology Disorder",
        "Bone Marrow Failure",
        "Dyskeratosis Congenita",
        "Telomere Biology Disorders"
      ],
      "interventions": [
        {
          "name": "Total Body Irradiation (TBI) (Plan 1)",
          "type": "DRUG"
        },
        {
          "name": "Cyclophosphamide (CY) (Plan 1)",
          "type": "DRUG"
        },
        {
          "name": "Fludarabine (FLU)",
          "type": "DRUG"
        },
        {
          "name": "Methylprednisolone (MP)",
          "type": "DRUG"
        },
        {
          "name": "Donor mobilized PBSC infusion",
          "type": "DEVICE"
        },
        {
          "name": "G-CSF",
          "type": "DRUG"
        },
        {
          "name": "Cyclophosphamide (CY) (Plan 2)",
          "type": "DRUG"
        },
        {
          "name": "Rituximab",
          "type": "DRUG"
        },
        {
          "name": "Busulfan",
          "type": "DRUG"
        },
        {
          "name": "Alemtuzumab",
          "type": "DRUG"
        },
        {
          "name": "Melphalan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "Up to 65 Years"
      },
      "enrollment_count": 48,
      "start_date": "2018-11-13",
      "completion_date": "2029-01-05",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03579875"
    },
    {
      "nct_id": "NCT05868499",
      "title": "Rollover Study From EXG-US-01",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Telomere Biology Disorders With Bone Marrow Failure"
      ],
      "interventions": [
        {
          "name": "EXG34217",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Elixirgen Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2024-01-01",
      "completion_date": "2027-01-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-12",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05868499"
    },
    {
      "nct_id": "NCT06430853",
      "title": "Psychobiological Interventions in Pregnancy",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy Complications",
        "Mental Health Issue",
        "Depression, Anxiety",
        "Pregnancy, High Risk",
        "Biological Clock Disturbance"
      ],
      "interventions": [
        {
          "name": "Step count goal",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Actigraph watch",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 88,
      "start_date": "2025-01-13",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06430853"
    },
    {
      "nct_id": "NCT04959188",
      "title": "Needs Assessment for Individuals and Families Affected by Dyskeratosis Congenita (DC) and Related Telomere Biology Disorders (TBD)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dyskeratosis Congenita",
        "Telomere Biology Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 53,
      "start_date": "2021-09-09",
      "completion_date": "2023-07-05",
      "has_results": false,
      "last_update_posted_date": "2024-12-11",
      "last_synced_at": "2026-05-22T07:48:28.203Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04959188"
    }
  ]
}