{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Temporomandibular+Joint+Dysfunction+Syndrome",
    "query": {
      "condition": "Temporomandibular Joint Dysfunction Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Temporomandibular+Joint+Dysfunction+Syndrome&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:14:03.164Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03512769",
      "title": "Feasibility Testing of a New Way to Support the Jaw During 3rd Molar Extractions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Impacted Third Molar Tooth",
        "Temporomandibular Joint Dysfunction Syndrome"
      ],
      "interventions": [
        {
          "name": "Restful Jaw Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 19,
      "start_date": "2018-06-01",
      "completion_date": "2018-12-30",
      "has_results": false,
      "last_update_posted_date": "2020-08-13",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03512769"
    },
    {
      "nct_id": "NCT00001601",
      "title": "Evaluation and Treatment of Oral Soft Tissue Diseases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aphthous Stomatitis",
        "Burning Mouth Syndrome",
        "Lichen Planus",
        "Mouth Disease",
        "Temporomandibular Joint Disorder"
      ],
      "interventions": [
        {
          "name": "Electrocardiogram",
          "type": "PROCEDURE"
        },
        {
          "name": "Biopsies",
          "type": "PROCEDURE"
        },
        {
          "name": "Diagnostic imaging",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 999,
      "start_date": "1997-08",
      "completion_date": "2002-08",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001601"
    },
    {
      "nct_id": "NCT03223298",
      "title": "Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain, Head",
        "Pain Syndrome",
        "Temporomandibular Disorder",
        "Myofascial Pain Syndrome",
        "Myofascial Pain"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin type A",
          "type": "DRUG"
        },
        {
          "name": "0.9% Sodium Chloride Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 75,
      "start_date": "2018-08-31",
      "completion_date": "2020-03-13",
      "has_results": true,
      "last_update_posted_date": "2023-02-14",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • New York, New York",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03223298"
    },
    {
      "nct_id": "NCT00716807",
      "title": "Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Temporomandibular Joint Dysfunction Syndrome",
        "Burning Mouth Syndrome"
      ],
      "interventions": [
        {
          "name": "nalbuphine plus naloxone",
          "type": "DRUG"
        },
        {
          "name": "nalbuphine plus placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2008-01",
      "completion_date": "2010-06",
      "has_results": true,
      "last_update_posted_date": "2016-05-20",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00716807"
    },
    {
      "nct_id": "NCT05754190",
      "title": "Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Pain",
        "Acute Pain",
        "Post Operative Pain",
        "Fibromyalgia, Primary",
        "Fibromyalgia, Secondary",
        "Fibromyalgia",
        "Irritable Bowel Syndrome",
        "Chronic Headache Disorder",
        "Chronic Migraine",
        "Chronic Pelvic Pain Syndrome",
        "Temporomandibular Joint Disorders",
        "Endometriosis-related Pain",
        "Arthritis",
        "Chronic Low-back Pain",
        "Failed Back Surgery Syndrome",
        "Post Herpetic Neuralgia",
        "Neuropathic Pain",
        "Painful Diabetic Neuropathy",
        "Painful Bladder Syndrome",
        "Trauma-related Wound",
        "Trauma, Multiple",
        "Chronic Pain Syndrome",
        "Chronic Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "SOMA pain manager smartphone application",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 800,
      "start_date": "2023-06-20",
      "completion_date": "2026-05-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-19",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05754190"
    },
    {
      "nct_id": "NCT01912391",
      "title": "Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Borderline Personality Disorder"
      ],
      "interventions": [
        {
          "name": "Selegiline",
          "type": "DRUG"
        },
        {
          "name": "Placebo (for Selegiline)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mood and Anxiety Research, Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2012-10",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2015-10-08",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "Fresno, California",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01912391"
    },
    {
      "nct_id": "NCT00870922",
      "title": "Effects of Masseter Manual Therapy on Temporomandibular Dysfunction",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Temporomandibular Joint",
        "Temporomandibular Joint Dysfunction Syndrome",
        "Temporomandibular Joint Disorder"
      ],
      "interventions": [
        {
          "name": "Active release techniques",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Logan College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2009-03",
      "completion_date": "2009-05",
      "has_results": false,
      "last_update_posted_date": "2009-03-27",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "Chesterfield, Missouri",
      "locations": [
        {
          "city": "Chesterfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00870922"
    },
    {
      "nct_id": "NCT02295644",
      "title": "Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Temporomandibular Joint Dysfunction Syndrome"
      ],
      "interventions": [
        {
          "name": "Ultrasound Sonicator 740",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2014-11",
      "completion_date": "2015-10",
      "has_results": true,
      "last_update_posted_date": "2018-06-07",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02295644"
    },
    {
      "nct_id": "NCT02202070",
      "title": "Botox for Treatment of TMJ Disorder With Bruxism",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Temporomandibular Joint Disorders",
        "Bruxism",
        "Temporomandibular Joint Dysfunction Syndrome",
        "Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint"
      ],
      "interventions": [
        {
          "name": "onabotulinumtoxinA",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-01",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02202070"
    },
    {
      "nct_id": "NCT02892994",
      "title": "Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Temporomandibular Joint Dysfunction Syndrome"
      ],
      "interventions": [
        {
          "name": "ultrasound",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 23,
      "start_date": "2016-04",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-09-08",
      "last_synced_at": "2026-05-22T04:14:03.164Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02892994"
    }
  ]
}