{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Thoracic+Aorta",
    "query": {
      "condition": "Thoracic Aorta"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 108,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Thoracic+Aorta&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T18:47:52.741Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05082454",
      "title": "Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aortic Valve Disease"
      ],
      "interventions": [
        {
          "name": "Open repair",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "JOTEC GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 108,
      "start_date": "2021-10-20",
      "completion_date": "2029-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-05",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 3,
      "location_summary": "Danville, Pennsylvania • Houston, Texas • Richmond, Virginia",
      "locations": [
        {
          "city": "Danville",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05082454"
    },
    {
      "nct_id": "NCT01959503",
      "title": "Progel Vascular Sealant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Valve Stenosis",
        "Aneurysm of Ascending Aorta",
        "Aortic Valve Disorder",
        "Bicuspid Valve Disorder"
      ],
      "interventions": [
        {
          "name": "Progel Vascular Sealant",
          "type": "DEVICE"
        },
        {
          "name": "Gelfoam Plus",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "C. R. Bard",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 158,
      "start_date": "2013-11",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2017-04-10",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 19,
      "location_summary": "Los Angeles, California • Aurora, Colorado • Gainesville, Florida + 16 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Pocatello",
          "state": "Idaho"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01959503"
    },
    {
      "nct_id": "NCT00606190",
      "title": "Prospective Randomized Study of Brain Protection During Aortic Arch Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aneurysm of Aortic Arch"
      ],
      "interventions": [
        {
          "name": "Retrograde brain perfusion",
          "type": "PROCEDURE"
        },
        {
          "name": "Antegrade brain perfusion",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "21 Years to 74 Years"
      },
      "enrollment_count": 123,
      "start_date": "2003-06",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2017-02-17",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00606190"
    },
    {
      "nct_id": "NCT01671618",
      "title": "Point-of-Care Focused Cardiac Ultrasound in Assessing the Thoracic Aorta",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aortic Aneurysm, Thoracic",
        "Aortic Dissection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 97,
      "start_date": "2012-07",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2016-06-30",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01671618"
    },
    {
      "nct_id": "NCT00802984",
      "title": "Endovascular Repair of Descending Thoracic Aortic Aneurysms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic"
      ],
      "interventions": [
        {
          "name": "Endovascular thoracic aortic aneurysm repair using TALENT TAA Stent Graft System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2002-01",
      "completion_date": "2005-12",
      "has_results": false,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00802984"
    },
    {
      "nct_id": "NCT07490015",
      "title": "Blunt Traumatic Aortic Injury",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Blunt Traumatic Aortic Injury",
        "BTAI"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Methodist Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2024-04-08",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07490015"
    },
    {
      "nct_id": "NCT00110201",
      "title": "The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "Acute Renal Failure",
        "Death"
      ],
      "interventions": [
        {
          "name": "Nesiritide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ejaz, Abulate A, MD",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2005-03",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00110201"
    },
    {
      "nct_id": "NCT00508118",
      "title": "NICardipine Neuroprotection in AortiC Surgery (NICNACS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic"
      ],
      "interventions": [
        {
          "name": "Nicardipine",
          "type": "DRUG"
        },
        {
          "name": "0.9% saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2008-01",
      "completion_date": "2008-04",
      "has_results": true,
      "last_update_posted_date": "2014-08-01",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00508118"
    },
    {
      "nct_id": "NCT00692991",
      "title": "Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myocardial Infarction",
        "Angina, Unstable",
        "Cardiomyopathy, Hypertrophic"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "1999-10",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-02-23",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00692991"
    },
    {
      "nct_id": "NCT02201589",
      "title": "Feasibility of Endovascular Repair Of Ascending Aortic Pathologies",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Dissection",
        "Intramural Hematoma",
        "Penetrating Ulcer",
        "Pseudoaneurysm"
      ],
      "interventions": [
        {
          "name": "Endovascular repair with Valiant PS-IDE Stent Graft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rodney A. White, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2013-11",
      "completion_date": "2033-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-06",
      "last_synced_at": "2026-07-22T18:47:52.741Z",
      "location_count": 3,
      "location_summary": "Long Beach, California • Los Angeles, California • Torrance, California",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02201589"
    }
  ]
}