{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Thoracic+Aortic+Disease",
    "query": {
      "condition": "Thoracic Aortic Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 96,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Thoracic+Aortic+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T14:37:21.969Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00508118",
      "title": "NICardipine Neuroprotection in AortiC Surgery (NICNACS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic"
      ],
      "interventions": [
        {
          "name": "Nicardipine",
          "type": "DRUG"
        },
        {
          "name": "0.9% saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2008-01",
      "completion_date": "2008-04",
      "has_results": true,
      "last_update_posted_date": "2014-08-01",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00508118"
    },
    {
      "nct_id": "NCT00110201",
      "title": "The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "Acute Renal Failure",
        "Death"
      ],
      "interventions": [
        {
          "name": "Nesiritide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ejaz, Abulate A, MD",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2005-03",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00110201"
    },
    {
      "nct_id": "NCT00608829",
      "title": "GORE TAG® Thoracic Endoprosthesis - 45 mm for the Treatment of Aneurysms of the Descending Thoracic Aorta",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic"
      ],
      "interventions": [
        {
          "name": "GORE TAG® Thoracic Endoprosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2007-02",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2015-03-05",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00608829"
    },
    {
      "nct_id": "NCT04005976",
      "title": "Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aortic Aneurysm",
        "Aortic Dissection",
        "Aortic Diseases"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 5000,
      "start_date": "2016-06-15",
      "completion_date": "2037-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-02",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 14,
      "location_summary": "Newport Beach, California • Sacramento, California • Lexington, Kentucky + 8 more",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04005976"
    },
    {
      "nct_id": "NCT02818972",
      "title": "RelayPro Thoracic Stent-Graft in Subjects With Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic",
        "Penetrating Ulcer"
      ],
      "interventions": [
        {
          "name": "RelayPro",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bolton Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2017-05-10",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Irvine, California + 17 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02818972"
    },
    {
      "nct_id": "NCT03536312",
      "title": "Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ascending Aortic Aneurysm Enlargement",
        "Ascending Aorta Aneurysm"
      ],
      "interventions": [
        {
          "name": "Thoracic Aortic Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Ottawa Heart Institute Research Corporation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 610,
      "start_date": "2018-09-01",
      "completion_date": "2035-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-22",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 15,
      "location_summary": "San Francisco, California • Boston, Massachusetts • Ann Arbor, Michigan + 11 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03536312"
    },
    {
      "nct_id": "NCT04545502",
      "title": "PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aneurysm",
        "Dissection",
        "Aortic Root Aneurysm",
        "Aortic Root Dissection",
        "Carotid Artery Injuries",
        "Aortic Arch",
        "Bypass Extremity Graft",
        "Occlusive Vascular Disease",
        "Aortic Diseases"
      ],
      "interventions": [
        {
          "name": "Gelsoft Plus Vascular Graft",
          "type": "DEVICE"
        },
        {
          "name": "Vascular Bypass Graft",
          "type": "DEVICE"
        },
        {
          "name": "Cardiovascular Patch",
          "type": "DEVICE"
        },
        {
          "name": "Gelweave Vascular Graft",
          "type": "DEVICE"
        },
        {
          "name": "Gelweave Valsalva Vascular Graft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vascutek Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2021-02-17",
      "completion_date": "2037-01",
      "has_results": false,
      "last_update_posted_date": "2025-06-03",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 10,
      "location_summary": "Aurora, Colorado • Tampa, Florida • Indianapolis, Indiana + 7 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Greenville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04545502"
    },
    {
      "nct_id": "NCT04747626",
      "title": "B-SAFER: Branched Stented Anastomosis Frozen Elephant Trunk Repair",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thoracic Aortic Aneurysm",
        "Aortic Dissection",
        "Congenital Aortic Anomaly"
      ],
      "interventions": [
        {
          "name": "B-SAFER",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Eric Roselli, M. D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 590,
      "start_date": "2021-03-25",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-09",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04747626"
    },
    {
      "nct_id": "NCT00813358",
      "title": "Zenith TX2® Post-market Approval Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Descending Thoracic Aortic Aneurysm"
      ],
      "interventions": [
        {
          "name": "Zenith TX2® TAA Endovascular Graft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cook Research Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 115,
      "start_date": "2009-07-10",
      "completion_date": "2020-03-23",
      "has_results": true,
      "last_update_posted_date": "2021-06-04",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 24,
      "location_summary": "San Francisco, California • Aurora, Colorado • Gainesville, Florida + 20 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00813358"
    },
    {
      "nct_id": "NCT02291718",
      "title": "Thoracoabdominal Arortic CTA Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Thoracic Aortic Aneurysm"
      ],
      "interventions": [
        {
          "name": "Isovue",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2014-01",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2017-04-18",
      "last_synced_at": "2026-06-10T14:37:21.969Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02291718"
    }
  ]
}