{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Thoracic+Insufficiency+Syndrome",
    "query": {
      "condition": "Thoracic Insufficiency Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Thoracic+Insufficiency+Syndrome&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:46:56.596Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00796419",
      "title": "Comparative Evaluation of Albumin and Starch Effects in Acute Lung Injury (ALI)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lung Injury, Acute (ALI)",
        "Respiratory Distress Syndrome, Acute (ARDS)"
      ],
      "interventions": [
        {
          "name": "5% human albumin",
          "type": "DRUG"
        },
        {
          "name": "6% hetastarch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2009-01",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2017-04-28",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 4,
      "location_summary": "Atlanta, Georgia • Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00796419"
    },
    {
      "nct_id": "NCT02523352",
      "title": "Effects of PEEP on Heart and Lungs in Obese Subjects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Pulmonary Atelectasis",
        "Obesity Hypoventilation Syndrome",
        "Magnetic Resonance Imaging",
        "Respiratory Mechanics",
        "Electrical Impedance Tomography",
        "Trans-Thoracic Echocardiography"
      ],
      "interventions": [
        {
          "name": "Non-Invasive Ventilation",
          "type": "PROCEDURE"
        },
        {
          "name": "Esophageal catheter positioning",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 35,
      "start_date": "2018-04-05",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-11-17",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02523352"
    },
    {
      "nct_id": "NCT02582957",
      "title": "Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Sigh breaths",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 524,
      "start_date": "2016-04-01",
      "completion_date": "2022-10-08",
      "has_results": true,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 15,
      "location_summary": "Fresno, California • Los Angeles, California • Sacramento, California + 12 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02582957"
    },
    {
      "nct_id": "NCT04522817",
      "title": "CLBS119 for Repair of COVID-19 Induced Pulmonary Damage",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Covid-19"
      ],
      "interventions": [
        {
          "name": "CLBS119",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Lisata Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-10-05",
      "completion_date": "2021-05",
      "has_results": false,
      "last_update_posted_date": "2024-10-09",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04522817"
    },
    {
      "nct_id": "NCT06583395",
      "title": "Quest to Analyze One Thousand Humans Meditating",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amyotrophic Lateral Sclerosis (ALS)",
        "Angina, Stable",
        "Anxiety",
        "Asthma",
        "Atrial Fibrillation",
        "Cancer Brain",
        "Cancer, Breast",
        "Cancer Colon",
        "Cancer, Lung",
        "Cancer, Ovarian",
        "Cancer Prostate",
        "Cancer Skin",
        "Throat Cancer",
        "Lymphoma",
        "Cancer, Thyroid",
        "Cancer, Other",
        "Cerebral Palsy",
        "Chronic Fatigue Syndrome",
        "Cluster Headache",
        "Chronic Obstructive Pulmonary Disease (COPD)",
        "Chronic Kidney Diseases",
        "Crohn Disease",
        "Deafness",
        "Depression",
        "Diabetes",
        "Eczema",
        "Epilepsy",
        "Fibroids",
        "Fibromyalgia",
        "Heart Failure",
        "Hypertension",
        "Hyperthyroidism",
        "Hypothyroidism",
        "Irritable Bowel Syndrome (IBS)",
        "Infertility",
        "Lyme Disease",
        "Macular Degeneration",
        "Migraine",
        "Multiple Allergies",
        "Multiple Sclerosis",
        "Osteoarthritis",
        "Osteoporosis",
        "Ovarian Cysts",
        "Parkinson Disease",
        "Phantom Limb Pain",
        "Psoriasis",
        "Post Traumatic Stress Disorder (PTSD)",
        "Rheumatoid Arthritis",
        "Sjogrens Disease",
        "Spinal Cord Injury",
        "Spinal Stenosis",
        "Stroke",
        "Tension Headache",
        "Tinnitus",
        "Ulcerative Colitis"
      ],
      "interventions": [
        {
          "name": "Advanced multi-component meditation practice",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Tobias Moeller-Bertram",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 3000,
      "start_date": "2021-12-05",
      "completion_date": "2025-03-25",
      "has_results": false,
      "last_update_posted_date": "2024-11-01",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 1,
      "location_summary": "Palm Desert, California",
      "locations": [
        {
          "city": "Palm Desert",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06583395"
    },
    {
      "nct_id": "NCT04977830",
      "title": "Pulmonary Assessment in Thoracic Insufficiency Syndrome Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thoracic Insufficiency Syndrome"
      ],
      "interventions": [
        {
          "name": "Xenon-129",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Patrick Cahill, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2026-01",
      "completion_date": "2026-08-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04977830"
    },
    {
      "nct_id": "NCT02299362",
      "title": "The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Early Onset Scoliosis",
        "Congenital Spinal Deformities",
        "Infantile Idiopathic Scoliosis",
        "Neuromuscular Spinal Deformity",
        "Syndromic Spinal Deformity",
        "Thoracic Insufficiency Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Growing Spine Study Group",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Day to 18 Years"
      },
      "enrollment_count": 2602,
      "start_date": "2008-10",
      "completion_date": "2020-02-04",
      "has_results": false,
      "last_update_posted_date": "2020-02-06",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 19,
      "location_summary": "Little Rock, Arkansas • Los Angeles, California • San Diego, California + 16 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02299362"
    },
    {
      "nct_id": "NCT01601223",
      "title": "Local Assessment of Ventilatory Management During General Anesthesia for Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Surgery",
        "Anaesthesia",
        "Ventilator-Induced Lung Injury",
        "Lung Injury",
        "Pneumonia",
        "Pneumothorax",
        "Respiratory Distress Syndrome, Adult",
        "Respiratory Insufficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "European Society of Anaesthesiology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10690,
      "start_date": "2013-01",
      "completion_date": "2013-11",
      "has_results": false,
      "last_update_posted_date": "2015-10-14",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 3,
      "location_summary": "Aurora, Colorado • Boston, Massachusetts • Rochester, Minnesota",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01601223"
    },
    {
      "nct_id": "NCT00585234",
      "title": "Tools for the Objective Clinical Assessment of Pediatric Spinal Deformity",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Thoracic Insufficiency Syndrome",
        "TIS"
      ],
      "interventions": [
        {
          "name": "Digital Photography",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Year to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2005-12",
      "completion_date": "2012-03",
      "has_results": false,
      "last_update_posted_date": "2024-01-09",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00585234"
    },
    {
      "nct_id": "NCT02241954",
      "title": "Vertical Expandable Prosthetic Titanium Rib (VEPTR) for Thoracic Insufficiency Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Thoracic Insufficiency Syndrome (TIS)"
      ],
      "interventions": [
        {
          "name": "Synthes VEPTR (Vertical Expandable Prosthetic Titanium Rib)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Months to 17 Years"
      },
      "enrollment_count": 7,
      "start_date": "2010-11-11",
      "completion_date": "2020-02-28",
      "has_results": false,
      "last_update_posted_date": "2020-05-12",
      "last_synced_at": "2026-05-22T09:46:56.596Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02241954"
    }
  ]
}