{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tibia+Fracture&page=2",
    "query": {
      "condition": "Tibia Fracture",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tibia+Fracture&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:11:49.964Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00533377",
      "title": "ACTiF- Assessment of Closed Tibial Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "CP-533,536",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 276,
      "start_date": "2008-01",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2012-02-17",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 11,
      "location_summary": "Wichita, Kansas • Worcester, Massachusetts • Minneapolis, Minnesota + 7 more",
      "locations": [
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00533377"
    },
    {
      "nct_id": "NCT02781623",
      "title": "Quantifying Quadriceps Atrophy Following Tibial Plateau Fracture",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrophy"
      ],
      "interventions": [
        {
          "name": "MRI",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 13,
      "start_date": "2015-10",
      "completion_date": "2022-01-18",
      "has_results": false,
      "last_update_posted_date": "2022-11-16",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02781623"
    },
    {
      "nct_id": "NCT00853489",
      "title": "rhBMP-2 Versus Autograft in Critical Size Tibial Defects",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "recombinant bone morphogenetic protein 2",
          "type": "DEVICE"
        },
        {
          "name": "Autogenous iliac crest bone graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 33,
      "start_date": "2011-08",
      "completion_date": "2017-02-17",
      "has_results": true,
      "last_update_posted_date": "2018-10-25",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 13,
      "location_summary": "San Francisco, California • Denver, Colorado • Tampa, Florida + 10 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00853489"
    },
    {
      "nct_id": "NCT02534259",
      "title": "Mobile Monitoring of Fracture Healing",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "Force monitoring of external fixator struts",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 6,
      "start_date": "2015-08",
      "completion_date": "2018-03-14",
      "has_results": false,
      "last_update_posted_date": "2019-02-18",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02534259"
    },
    {
      "nct_id": "NCT03891888",
      "title": "Intramedullary Bone Grafting for Open Tibial Shaft Fractures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Fractures",
        "Nonunion of Fracture",
        "Delayed Union of Fracture"
      ],
      "interventions": [
        {
          "name": "Intramedullary Bone Graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2020-03-26",
      "completion_date": "2025-02",
      "has_results": false,
      "last_update_posted_date": "2024-05-22",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03891888"
    },
    {
      "nct_id": "NCT05521958",
      "title": "Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Shaft Fracture",
        "Tibial Plateau Fracture"
      ],
      "interventions": [
        {
          "name": "Acute injury without compartment syndrome",
          "type": "PROCEDURE"
        },
        {
          "name": "Acute injury with compartment syndrome",
          "type": "PROCEDURE"
        },
        {
          "name": "Exertional compartment syndrome",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-06-10",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05521958"
    },
    {
      "nct_id": "NCT04906642",
      "title": "Clinical Assessment of Next Science Solution on Gustilo and Anderson Type II and IIIA or IIIB Tibial Fractures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Wound Infection"
      ],
      "interventions": [
        {
          "name": "Next Science",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Next Science TM",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 17,
      "start_date": "2021-05-04",
      "completion_date": "2023-09-01",
      "has_results": false,
      "last_update_posted_date": "2023-11-03",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Columbus, Georgia",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Columbus",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04906642"
    },
    {
      "nct_id": "NCT01316289",
      "title": "Pilon Fracture Reduction and Functional Outcome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pilon Fracture of Tibia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "AO Clinical Investigation and Publishing Documentation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 117,
      "start_date": "2011-11",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2020-08-13",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 4,
      "location_summary": "Indianapolis, Indiana • Saint Paul, Minnesota • Jackson, Mississippi + 1 more",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01316289"
    },
    {
      "nct_id": "NCT05668182",
      "title": "A Case Series: TRUMATCH Graft Cage for Segmental Long Bone Defects",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tibia Fracture",
        "Humerus Fracture",
        "Femoral Fracture",
        "Long Bone Segmental Defect"
      ],
      "interventions": [
        {
          "name": "TRUMATCH Graft Cage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2021-06-29",
      "completion_date": "2026-06-29",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05668182"
    },
    {
      "nct_id": "NCT03042533",
      "title": "Union Rate of Transverse Tibia Fracture",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Closed Transverse Fracture of Shaft of Tibia"
      ],
      "interventions": [
        {
          "name": "Conventional Compression",
          "type": "DEVICE"
        },
        {
          "name": "Standard Backslapping",
          "type": "DEVICE"
        },
        {
          "name": "Dynamic Locking with Backslapping",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2017-02-01",
      "completion_date": "2018-05-29",
      "has_results": true,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-05-22T08:11:49.964Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03042533"
    }
  ]
}