{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tibial+Shaft+Fracture",
    "query": {
      "condition": "Tibial Shaft Fracture"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tibial+Shaft+Fracture&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:33:59.230Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03598530",
      "title": "Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tibial Fracture",
        "Fracture of the Tibia Type AO/OTA 42"
      ],
      "interventions": [
        {
          "name": "Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "AO Clinical Investigation and Publishing Documentation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2019-04-04",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 3,
      "location_summary": "New York, New York • Nashville, Tennessee",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03598530"
    },
    {
      "nct_id": "NCT05627479",
      "title": "MAGIK for Femoral/Tibial Shaft Fractures",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Femoral Shaft Fracture",
        "Tibial Shaft Fracture"
      ],
      "interventions": [
        {
          "name": "GIK solution",
          "type": "DRUG"
        },
        {
          "name": "Isotonic Normal Saline Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-12-01",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-03-06",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05627479"
    },
    {
      "nct_id": "NCT00038129",
      "title": "SPRINT - Randomized Trial of Tibial Fracture Fixation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Fracture"
      ],
      "interventions": [
        {
          "name": "Intramedullary nail implant",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 1200,
      "start_date": "2002-05",
      "completion_date": "2006-11",
      "has_results": false,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 16,
      "location_summary": "San Francisco, California • Jacksonville, Florida • Evansville, Indiana + 13 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Evansville",
          "state": "Indiana"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00038129"
    },
    {
      "nct_id": "NCT01238523",
      "title": "Study of Tibial Shaft Fractures in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Shaft Fractures in Children"
      ],
      "interventions": [
        {
          "name": "Long leg cast in full extension",
          "type": "PROCEDURE"
        },
        {
          "name": "Long leg cast with 45 degrees of flexion",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "4 Years to 14 Years"
      },
      "enrollment_count": 81,
      "start_date": "2007-05",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2017-08-17",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01238523"
    },
    {
      "nct_id": "NCT03891888",
      "title": "Intramedullary Bone Grafting for Open Tibial Shaft Fractures",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Fractures",
        "Nonunion of Fracture",
        "Delayed Union of Fracture"
      ],
      "interventions": [
        {
          "name": "Intramedullary Bone Graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2020-03-26",
      "completion_date": "2025-02",
      "has_results": false,
      "last_update_posted_date": "2024-05-22",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03891888"
    },
    {
      "nct_id": "NCT03382041",
      "title": "Carbon Fiber Implants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Shaft Fractures"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Implant",
          "type": "DEVICE"
        },
        {
          "name": "Titanium Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2017-05-23",
      "completion_date": "2021-03-31",
      "has_results": true,
      "last_update_posted_date": "2023-07-25",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03382041"
    },
    {
      "nct_id": "NCT06078371",
      "title": "Opioid-Free Pain Treatment in Trauma Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Femoral Neck Fractures",
        "Intertrochanteric Fractures",
        "Femoral Shaft Fracture",
        "Distal Femur Fracture",
        "Patella Fracture",
        "Tibial Shaft Fracture with or Without Associated Fibula Fracture",
        "Ankle Fracture (bimalleolar Equivalent, Bimalleolar, or Trimalleolar)",
        "Tibial Pilon Fracture",
        "Talar Head, Neck, Body, or Process Fractures",
        "Calcaneus Fractures",
        "Lisfranc Injuries",
        "Isolated or Multiple Metatarsal Fractures",
        "Phalanx Fractures of the Foot, Single or Multiple",
        "Clavicle Fractures",
        "Proximal Humerus Fractures",
        "Humeral Shaft Fractures",
        "Distal Humerus Fractures (intra or Extra-articular)",
        "Olecranon Fractures",
        "Radial Head or Neck Fractures",
        "Elbow Fractures Involving a Combination of Fractures of the Radius and Uln",
        "Forearm Fractures (both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft)",
        "Distal Radius Fractures"
      ],
      "interventions": [
        {
          "name": "Opioid-free pain treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2023-11-01",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06078371"
    },
    {
      "nct_id": "NCT03042533",
      "title": "Union Rate of Transverse Tibia Fracture",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Closed Transverse Fracture of Shaft of Tibia"
      ],
      "interventions": [
        {
          "name": "Conventional Compression",
          "type": "DEVICE"
        },
        {
          "name": "Standard Backslapping",
          "type": "DEVICE"
        },
        {
          "name": "Dynamic Locking with Backslapping",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2017-02-01",
      "completion_date": "2018-05-29",
      "has_results": true,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03042533"
    },
    {
      "nct_id": "NCT02786498",
      "title": "Optimal Vitamin D3 Supplementation Strategies for Acute Fracture Healing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fracture"
      ],
      "interventions": [
        {
          "name": "Vitamin D3",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 102,
      "start_date": "2016-11-21",
      "completion_date": "2021-12-01",
      "has_results": true,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02786498"
    },
    {
      "nct_id": "NCT00533377",
      "title": "ACTiF- Assessment of Closed Tibial Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "CP-533,536",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 276,
      "start_date": "2008-01",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2012-02-17",
      "last_synced_at": "2026-06-11T01:33:59.230Z",
      "location_count": 11,
      "location_summary": "Wichita, Kansas • Worcester, Massachusetts • Minneapolis, Minnesota + 7 more",
      "locations": [
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00533377"
    }
  ]
}