{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tissue+Oxygenation",
    "query": {
      "condition": "Tissue Oxygenation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 54,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tissue+Oxygenation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T18:21:56.666Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04709419",
      "title": "Celliant Socks to Increase Tissue Oxygenation and Complete Wound Closure in Diabetic Foot Wounds",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Celliant Diabetic Medical Socks",
          "type": "DEVICE"
        },
        {
          "name": "Control (placebo) Medical Socks",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2022-07-28",
      "completion_date": "2023-04-04",
      "has_results": true,
      "last_update_posted_date": "2025-01-15",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04709419"
    },
    {
      "nct_id": "NCT01418690",
      "title": "Changes in Tissue Oxygenation Following Regional Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anesthesia, Local"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 29,
      "start_date": "2011-09",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2016-11-29",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01418690"
    },
    {
      "nct_id": "NCT05983744",
      "title": "Pulsatile Perfusion Therapy Phase II",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemorrhage"
      ],
      "interventions": [
        {
          "name": "0 Hz Control",
          "type": "OTHER"
        },
        {
          "name": "0.1 Hz PPT",
          "type": "OTHER"
        },
        {
          "name": "0.05 Hz PPT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Caroline Rickards",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 21,
      "start_date": "2020-02-27",
      "completion_date": "2021-12-17",
      "has_results": false,
      "last_update_posted_date": "2023-08-09",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05983744"
    },
    {
      "nct_id": "NCT02146885",
      "title": "The Use of Diffuse Optical Spectroscopy to Characterize in Response to Weight-Loss Intervention",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Overweight"
      ],
      "interventions": [
        {
          "name": "Weight Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 21,
      "start_date": "2013-01-08",
      "completion_date": "2017-01-13",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02146885"
    },
    {
      "nct_id": "NCT07166341",
      "title": "Accuracy Verification of the INVOS PM7100",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tissue Oxygenation"
      ],
      "interventions": [
        {
          "name": "Observational",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic - MITG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "46 Years",
        "sex": "ALL",
        "summary": "18 Years to 46 Years"
      },
      "enrollment_count": 48,
      "start_date": "2025-09-29",
      "completion_date": "2026-04-23",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07166341"
    },
    {
      "nct_id": "NCT01760044",
      "title": "Noninvasive Assessment of Tissue Perfusion Status in Critically Ill Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Shock"
      ],
      "interventions": [
        {
          "name": "Tissue oxygenation monitoring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "30 Days to 18 Years"
      },
      "enrollment_count": 46,
      "start_date": "2013-01",
      "completion_date": "2014-11",
      "has_results": false,
      "last_update_posted_date": "2017-05-23",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01760044"
    },
    {
      "nct_id": "NCT05172791",
      "title": "Decreasing Unnecessary Antibiotics Prescribed for Possible Pneumonia Despite Normal Respiratory Rate and Oxygenation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pneumonia"
      ],
      "interventions": [
        {
          "name": "Antibiotic stewardship messaging",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 643,
      "start_date": "2022-07-11",
      "completion_date": "2024-10-08",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05172791"
    },
    {
      "nct_id": "NCT01573390",
      "title": "Non Invasive and Non-Contact Imaging Of Tissue Oxygenation and Vascular Reactivity",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Quantitative Validation of Imaging System"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Chandan K Sen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2022-04-28",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01573390"
    },
    {
      "nct_id": "NCT03569774",
      "title": "Individualized vs Low PEEP in One Lung Ventilation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "One-Lung Ventilation",
        "Obesity",
        "Lung Diseases"
      ],
      "interventions": [
        {
          "name": "One-lung ventilation with individualized PEEP",
          "type": "PROCEDURE"
        },
        {
          "name": "One-lung ventilation with low PEEP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Dionne Peacher",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-08-14",
      "completion_date": "2021-05-19",
      "has_results": false,
      "last_update_posted_date": "2021-07-06",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03569774"
    },
    {
      "nct_id": "NCT03483623",
      "title": "NATO Litter: Fluid Immersion System (FIS) Versus Traditional Mattress for Pressure Dispersion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pressure Distribution",
        "Military Litters",
        "Peak Pressure Index",
        "Total Surface Area",
        "Tissue Perfusion"
      ],
      "interventions": [
        {
          "name": "NATO WELP combination",
          "type": "OTHER"
        },
        {
          "name": "NATO FIS combination",
          "type": "OTHER"
        },
        {
          "name": "RAVEN WELP combination",
          "type": "OTHER"
        },
        {
          "name": "RAVEN FIS combination",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "David Grant U.S. Air Force Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2018-03-21",
      "completion_date": "2018-10-19",
      "has_results": true,
      "last_update_posted_date": "2020-03-25",
      "last_synced_at": "2026-06-10T18:21:56.666Z",
      "location_count": 1,
      "location_summary": "Travis Air Force Base, California",
      "locations": [
        {
          "city": "Travis Air Force Base",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03483623"
    }
  ]
}