{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tonsil+Disease&page=2",
    "query": {
      "condition": "Tonsil Disease",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tonsil+Disease&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T06:22:30.340Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01349205",
      "title": "Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Enlargement of Tonsil or Adenoid"
      ],
      "interventions": [
        {
          "name": "Caffeine and sodium Benzoate 10 mg/kg IV",
          "type": "DRUG"
        },
        {
          "name": "Caffeine and Sodium Benzoate 20 mg/kg IV",
          "type": "DRUG"
        },
        {
          "name": "0.9 NS Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "2 Years to 12 Years"
      },
      "enrollment_count": 42,
      "start_date": "2010-03",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2016-05-13",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01349205"
    },
    {
      "nct_id": "NCT03884296",
      "title": "Response to Live Attenuated Influenza Vaccine in Tonsillar Tissues and Blood",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Influenza"
      ],
      "interventions": [
        {
          "name": "FluMist",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "2 Years to 49 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-04-15",
      "completion_date": "2023-11-17",
      "has_results": false,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03884296"
    },
    {
      "nct_id": "NCT01389349",
      "title": "Acupuncture for Tonsillectomy Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Children",
        "Postoperative Pain",
        "Tonsillar Hypertrophy",
        "Obstructive Sleep Apnea",
        "Chronic Tonsillitis"
      ],
      "interventions": [
        {
          "name": "Acupuncture",
          "type": "OTHER"
        },
        {
          "name": "Sham Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's ENT of San Diego, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Years to 17 Years"
      },
      "enrollment_count": 130,
      "start_date": "2011-07",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2012-05-18",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 2,
      "location_summary": "El Centro, California • San Diego, California",
      "locations": [
        {
          "city": "El Centro",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01389349"
    },
    {
      "nct_id": "NCT04551196",
      "title": "Management of Post-Tonsillectomy Pain in Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Tonsillar Hypertrophy",
        "Tonsillitis"
      ],
      "interventions": [
        {
          "name": "Alternating Acetaminophen and Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Combined Acetaminophen and Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "4 Years to 17 Years"
      },
      "enrollment_count": 50,
      "start_date": "2020-09-28",
      "completion_date": "2022-11-10",
      "has_results": true,
      "last_update_posted_date": "2024-07-11",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04551196"
    },
    {
      "nct_id": "NCT05154214",
      "title": "Surgical Treatment of Children With OSA and Small Tonsils or Down Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea of Child"
      ],
      "interventions": [
        {
          "name": "Adenotonsillectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Drug-induced sleep endoscopy directed surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Years to 18 Years"
      },
      "enrollment_count": 30,
      "start_date": "2021-11-09",
      "completion_date": "2024-10-11",
      "has_results": false,
      "last_update_posted_date": "2025-09-29",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05154214"
    },
    {
      "nct_id": "NCT05022368",
      "title": "Oral Device Clinical Trial",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tonsil Disease",
        "Dental Diseases",
        "Adenoid; Disorder (and Tonsils)"
      ],
      "interventions": [
        {
          "name": "LabraGuard",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 250,
      "start_date": "2021-05-24",
      "completion_date": "2024-08-01",
      "has_results": false,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05022368"
    },
    {
      "nct_id": "NCT00466544",
      "title": "Randomized Controlled Study of Plasmaknife Tonsillectomy Versus Monopolar Tonsillectomy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Obstructive Tonsillar Hypertrophy",
        "Tonsillitis"
      ],
      "interventions": [
        {
          "name": "Plasmaknife",
          "type": "DEVICE"
        },
        {
          "name": "Monopolar",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "4 Years to 16 Years"
      },
      "enrollment_count": 100,
      "start_date": "2007-05",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2007-04-27",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00466544"
    },
    {
      "nct_id": "NCT01326923",
      "title": "Induction Chemo Then Concurrent Chemoradiotherapy With Cetuximab in Locally Advanced Head and Neck Squamous Cell Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Head and Neck Squamous Cell Cancer"
      ],
      "interventions": [
        {
          "name": "Cetuximab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Louisiana State University Health Sciences Center Shreveport",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2010-06",
      "completion_date": "2014-02",
      "has_results": true,
      "last_update_posted_date": "2020-10-09",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "Shreveport, Louisiana",
      "locations": [
        {
          "city": "Shreveport",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01326923"
    },
    {
      "nct_id": "NCT06915038",
      "title": "ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Squamous Cell Carcinoma of Oropharynx",
        "HPV Positive Cancer",
        "Throat Cancer",
        "Tonsil Cancer"
      ],
      "interventions": [
        {
          "name": "NavDx",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Adjuvant Radiation 30 Gray",
          "type": "RADIATION"
        },
        {
          "name": "Adjuvant Radiation 40 Gray",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "RADIATION"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2025-06-11",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 2,
      "location_summary": "Carmel, Indiana • Indianapolis, Indiana",
      "locations": [
        {
          "city": "Carmel",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06915038"
    },
    {
      "nct_id": "NCT06326983",
      "title": "Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tonsillitis",
        "Post-operative Nausea and Vomiting (PONV)",
        "Emergence Delirium",
        "Opioid Analgesic Adverse Reaction",
        "Anesthesia",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Morphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 62,
      "start_date": "2024-05-09",
      "completion_date": "2026-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-06-11T06:22:30.340Z",
      "location_count": 1,
      "location_summary": "Waltham, Massachusetts",
      "locations": [
        {
          "city": "Waltham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06326983"
    }
  ]
}