{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tooth+Abnormalities",
    "query": {
      "condition": "Tooth Abnormalities"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 70,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tooth+Abnormalities&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T15:13:56.046Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01193088",
      "title": "Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Charcot-Marie-Tooth Disease, Type Ia (Disorder)",
        "HMSN"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1050,
      "start_date": "2010-05",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 17,
      "location_summary": "Los Angeles, California • Palo Alto, California • Aurora, Colorado + 13 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01193088"
    },
    {
      "nct_id": "NCT02561702",
      "title": "Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Charcot Marie Tooth Disease"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Mexiletine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2015-09",
      "completion_date": "2016-12-31",
      "has_results": true,
      "last_update_posted_date": "2018-03-26",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02561702"
    },
    {
      "nct_id": "NCT03198520",
      "title": "REFRAME RPD Post-Market Clinical Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Missing Teeth",
        "Dental Wear"
      ],
      "interventions": [
        {
          "name": "Solvay Dental 360™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Solvay Dental 360",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2017-06-06",
      "completion_date": "2019-10-07",
      "has_results": true,
      "last_update_posted_date": "2020-11-19",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03198520"
    },
    {
      "nct_id": "NCT03036566",
      "title": "Lithium Disilicate (CAD/CAM) Fixed Partial Dentures (FPD) Clinical Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Missing Tooth"
      ],
      "interventions": [
        {
          "name": "Lithium disilicate ceramic (Ivoclar)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2014-03",
      "completion_date": "2020-03-05",
      "has_results": true,
      "last_update_posted_date": "2024-07-25",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03036566"
    },
    {
      "nct_id": "NCT06651502",
      "title": "Efficacy of a Dental Implant System for Immediate Restoration",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Missing Teeth"
      ],
      "interventions": [
        {
          "name": "dental implant placement and immediate provisionalization",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Harvard Medical School (HMS and HSDM)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "20 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-01-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06651502"
    },
    {
      "nct_id": "NCT04798378",
      "title": "NuroSleeve Powered Brace & Stimulation System to Restore Arm Function",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurologic Diseases",
        "Hemiparesis",
        "Quadriplegia",
        "Muscular Dystrophies",
        "Arthrogryposis",
        "Spinal Cord Injuries",
        "Charcot-Marie-Tooth",
        "Stroke",
        "Weakness of Extremities as Sequela of Stroke",
        "Weakness Due to Upper Motor Neuron Dysfunction",
        "Amyotrophic Lateral Sclerosis",
        "Spinal Muscular Atrophy",
        "Arm Paralysis",
        "Cerebral Palsy"
      ],
      "interventions": [
        {
          "name": "Neurosleeve",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2020-04-16",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-04-09",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 2,
      "location_summary": "Wilmington, Delaware • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04798378"
    },
    {
      "nct_id": "NCT05205616",
      "title": "Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Complication",
        "Paresthesia",
        "Fracture",
        "Nerve Injury",
        "Nerve Entrapments",
        "Mandibular Nerve Injuries",
        "Mandibular Hypoplasia",
        "Mandibular Retrognathism",
        "Mandibular Hyperplasia",
        "Mandibular Prognathism"
      ],
      "interventions": [
        {
          "name": "Sonopet ultrasonic saw",
          "type": "DEVICE"
        },
        {
          "name": "Reciprocating saw",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "Up to 45 Years"
      },
      "enrollment_count": 32,
      "start_date": "2021-07-20",
      "completion_date": "2023-07-25",
      "has_results": true,
      "last_update_posted_date": "2025-06-04",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05205616"
    },
    {
      "nct_id": "NCT05011006",
      "title": "NT-3 Levels and Function in Individuals With CMT",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Charcot-Marie-Tooth Disease",
        "Peripheral Neuropathy",
        "Chronic Inflammatory Demyelinating Polyneuropathy"
      ],
      "interventions": [
        {
          "name": "NT3 blood draw",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Zarife Sahenk",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2027-11-13",
      "completion_date": "2030-06",
      "has_results": false,
      "last_update_posted_date": "2025-06-24",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05011006"
    },
    {
      "nct_id": "NCT07053969",
      "title": "The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Implantation",
        "Missing Teeth",
        "Periodontitis, Adult",
        "Mucositis"
      ],
      "interventions": [
        {
          "name": "Enamel Matrix Derivative",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "18 Years to 18 Years"
      },
      "enrollment_count": 32,
      "start_date": "2025-08-31",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2025-11-12",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07053969"
    },
    {
      "nct_id": "NCT02889835",
      "title": "Clinical Performance of Incremental and Bulk Fill Composites in Class II Restorations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Supreme Universal Restorative",
          "type": "DEVICE"
        },
        {
          "name": "Supreme Flowable Restorative",
          "type": "DEVICE"
        },
        {
          "name": "Bulk Fill Flowable Restorative",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Solventum US LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "19 Years to 90 Years"
      },
      "enrollment_count": 53,
      "start_date": "2016-03-22",
      "completion_date": "2021-07-03",
      "has_results": true,
      "last_update_posted_date": "2024-10-01",
      "last_synced_at": "2026-06-10T15:13:56.046Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02889835"
    }
  ]
}