{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tooth+Replacement",
    "query": {
      "condition": "Tooth Replacement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tooth+Replacement&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T14:53:47.511Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01547273",
      "title": "The Effect of Bone Grafts on Facial Gingival Profile in Maxillary Anterior Single Tooth Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Facial Gingival Profile"
      ],
      "interventions": [
        {
          "name": "bone graft inside socket only",
          "type": "PROCEDURE"
        },
        {
          "name": "bone graft inside and outside socket",
          "type": "PROCEDURE"
        },
        {
          "name": "no bone graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2012-03-20",
      "completion_date": "2016-04-07",
      "has_results": false,
      "last_update_posted_date": "2021-04-26",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 2,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01547273"
    },
    {
      "nct_id": "NCT06553300",
      "title": "Auto Transplantation of Wisdom Teeth",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autotransplantation of Wisdom Teeth",
        "Patelet Rich Fibrin"
      ],
      "interventions": [
        {
          "name": "Autotransplantation with PRF",
          "type": "PROCEDURE"
        },
        {
          "name": "Autotransplatation Only",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Cleveland Dental Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 20,
      "start_date": "2024-01-01",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-14",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06553300"
    },
    {
      "nct_id": "NCT04060784",
      "title": "Maxillary Anterior Immediate Tooth Replacement With and Without Socket-shield",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Teeth"
      ],
      "interventions": [
        {
          "name": "Immediate implant placement and provisionalization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2019-08-30",
      "completion_date": "2023-03-29",
      "has_results": false,
      "last_update_posted_date": "2024-11-20",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 2,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04060784"
    },
    {
      "nct_id": "NCT04082143",
      "title": "CATER: Comprehensive Alveolar and Tooth Esthetic Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Implant Failure Nos"
      ],
      "interventions": [
        {
          "name": "Allograft mucosal enhancement with dental implant",
          "type": "DEVICE"
        },
        {
          "name": "No allograft mucosal enhancement at time of dental implant placement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2019-08-25",
      "completion_date": "2022-12-20",
      "has_results": true,
      "last_update_posted_date": "2025-02-28",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04082143"
    },
    {
      "nct_id": "NCT01842958",
      "title": "Straumann Roxolid Multi-Center Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Jaw, Edentulous, Partially"
      ],
      "interventions": [
        {
          "name": "Straumann Bone Level Implants, 4.1 mm implant diameter",
          "type": "DEVICE"
        },
        {
          "name": "Straumann Bone Level Implants, 3.3 mm implant diameter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Institut Straumann AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2013-03",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2018-02-15",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 5,
      "location_summary": "Los Angeles, California • Boston, Massachusetts • New York, New York + 2 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01842958"
    },
    {
      "nct_id": "NCT01201876",
      "title": "DPBRN Reasons for Replacement or Repair of Dental Restorations",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dental Practice-Based Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 6368,
      "start_date": "2008-11",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2011-06-16",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 6,
      "location_summary": "Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01201876"
    },
    {
      "nct_id": "NCT06722482",
      "title": "Comparison of Two Types of Bone Grafts in Patients Who Need One of Their Front Teeth Removed and Replaced With an Implant",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ridge Preservation",
        "Allografts",
        "Extraction, Tooth",
        "Xenograft"
      ],
      "interventions": [
        {
          "name": "FDBA",
          "type": "DEVICE"
        },
        {
          "name": "CEBX",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2023-11-27",
      "completion_date": "2026-11-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-09",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06722482"
    },
    {
      "nct_id": "NCT01714024",
      "title": "Dental Implant Study Comparing Two Types of Metals Used for Dental Implants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Replacement"
      ],
      "interventions": [
        {
          "name": "Zimmer Trabecular Metal Test Cylinder",
          "type": "DEVICE"
        },
        {
          "name": "Zimmer Titanium Test Cylinder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 42,
      "start_date": "2012-10",
      "completion_date": "2015-05",
      "has_results": true,
      "last_update_posted_date": "2017-10-12",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01714024"
    },
    {
      "nct_id": "NCT00820235",
      "title": "Study Comparing Appearance and Function of Three Different Dental Implant Designs When Placed in Front Region of Upper Jaw",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Jaw, Edentulous, Partially"
      ],
      "interventions": [
        {
          "name": "OsseoSpeed™",
          "type": "DEVICE"
        },
        {
          "name": "NobelSpeedy™ Replace®",
          "type": "DEVICE"
        },
        {
          "name": "NanoTite™ Certain® PREVAIL®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Dentsply Sirona Implants and Consumables",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 141,
      "start_date": "2009-02",
      "completion_date": "2016-09",
      "has_results": true,
      "last_update_posted_date": "2020-05-07",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 3,
      "location_summary": "Iowa City, Iowa • Chapel Hill, North Carolina • Houston, Texas",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00820235"
    },
    {
      "nct_id": "NCT07191262",
      "title": "To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth"
      ],
      "interventions": [
        {
          "name": "0.12% CHX and Essential Oil mouthrinse",
          "type": "OTHER"
        },
        {
          "name": "2.6% EDTA and 0.2% EDTA mouth rinse",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-03-02",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-07-23T14:53:47.511Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07191262"
    }
  ]
}