{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Toothache", "query": { "condition": "Toothache" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 92, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Toothache&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-22T04:26:39.043Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00985439", "title": "Study of Diclofenac Capsules to Treat Dental Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dental Pain" ], "interventions": [ { "name": "Diclofenac Test (lower dose)", "type": "DRUG" }, { "name": "Diclofenac Test (upper dose)", "type": "DRUG" }, { "name": "Celecoxib 400 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Iroko Pharmaceuticals, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 202, "start_date": "2009-09", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2012-05-22", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Austin, Texas", "locations": [ { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00985439" }, { "nct_id": "NCT04642404", "title": "CBD for Dental Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Odontalgia", "Toothache" ], "interventions": [ { "name": "Epidiolex 100 mg/mL Oral Solution", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 64, "start_date": "2021-03-01", "completion_date": "2023-03-13", "has_results": true, "last_update_posted_date": "2024-05-09", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04642404" }, { "nct_id": "NCT02863575", "title": "A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/Caffeine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain" ], "interventions": [ { "name": "Ibuprofen/Caffeine", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "16 Years to 40 Years" }, "enrollment_count": 374, "start_date": "2017-10-24", "completion_date": "2018-04-06", "has_results": true, "last_update_posted_date": "2019-04-08", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02863575" }, { "nct_id": "NCT06330207", "title": "An Emergency Department (ED) Provider Centered Intervention for Non-Traumatic Dental Condition Management (NTDC)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Emergency Department Visit", "Odontalgia" ], "interventions": [ { "name": "Clinical decision support tool", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2026-01-15", "completion_date": "2027-08-01", "has_results": false, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06330207" }, { "nct_id": "NCT00574015", "title": "The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Toothache" ], "interventions": [ { "name": "hydrocodone/acetaminophen", "type": "DRUG" }, { "name": "bupivacaine (supraperiosteal nerve block)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Albany Medical College", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 18, "start_date": "2007-12", "completion_date": "2013-01", "has_results": false, "last_update_posted_date": "2014-03-24", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Albany, New York", "locations": [ { "city": "Albany", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00574015" }, { "nct_id": "NCT00542035", "title": "A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dental Pain" ], "interventions": [ { "name": "ARRY-371797, p38 inhibitor; oral", "type": "DRUG" }, { "name": "Placebo; oral", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 103, "start_date": "2007-11-11", "completion_date": "2008-02-11", "has_results": false, "last_update_posted_date": "2021-02-21", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 2, "location_summary": "San Marcos, Texas • Salt Lake City, Utah", "locations": [ { "city": "San Marcos", "state": "Texas" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00542035" }, { "nct_id": "NCT01929031", "title": "Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain, Postoperative", "Tooth Diseases" ], "interventions": [ { "name": "ibuprofen + caffeine", "type": "DRUG" }, { "name": "ibuprofen", "type": "DRUG" }, { "name": "caffeine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 562, "start_date": "2013-08", "completion_date": "2014-03", "has_results": true, "last_update_posted_date": "2016-11-16", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT01929031" }, { "nct_id": "NCT01115673", "title": "To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain" ], "interventions": [ { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Placebo Control", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "16 Years to 50 Years" }, "enrollment_count": 540, "start_date": "2010-06", "completion_date": "2011-01", "has_results": true, "last_update_posted_date": "2012-05-28", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT01115673" }, { "nct_id": "NCT01870973", "title": "Effect of Root Canal Treatment (Versus no Treatment) for Patients With Tooth Infections and Toothaches", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "root canal treatment, anesthesia, pain medications, and antibiotic", "type": "PROCEDURE" }, { "name": "no root canal treatment, anesthesia, pain medications, and antibiotic", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 108, "start_date": "2013-03", "completion_date": "2014-06", "has_results": true, "last_update_posted_date": "2015-06-18", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01870973" }, { "nct_id": "NCT00954356", "title": "Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dental Pain" ], "interventions": [ { "name": "XPF-001", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Xenon Pharmaceuticals Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 61, "start_date": "2009-09", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2012-07-16", "last_synced_at": "2026-05-22T04:26:39.043Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00954356" } ] }