{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Topical+Anesthesia&page=2",
    "query": {
      "condition": "Topical Anesthesia",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Topical+Anesthesia&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T15:17:01.884Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03799484",
      "title": "Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Forehead Rhytides",
        "Forehead Wrinkles"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin type A",
          "type": "DRUG"
        },
        {
          "name": "2.5% lidocaine/2.5% prilocaine",
          "type": "DRUG"
        },
        {
          "name": "petrolatum ointment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2019-01-04",
      "completion_date": "2019-06-14",
      "has_results": true,
      "last_update_posted_date": "2020-06-18",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03799484"
    },
    {
      "nct_id": "NCT00891163",
      "title": "Evaluate the Depth and Duration of Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Synera™ Topical Patch (70 mg lidocaine/70 mg tetracaine)",
          "type": "DRUG"
        },
        {
          "name": "Placebo Patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "ZARS Pharma Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 25,
      "start_date": "2006-12",
      "completion_date": "2007-04",
      "has_results": false,
      "last_update_posted_date": "2009-05-01",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00891163"
    },
    {
      "nct_id": "NCT01576770",
      "title": "In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain on Propofol IV Injection"
      ],
      "interventions": [
        {
          "name": "lidocaine/tetracaine transdermal patch (NDC 43469-864-01)",
          "type": "DEVICE"
        },
        {
          "name": "Gebauer's Ethyl Chloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 80,
      "start_date": "2012-04",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2012-04-12",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01576770"
    },
    {
      "nct_id": "NCT05269823",
      "title": "Topical Ice-therapy for Intravitreal Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia; Hypothermia",
        "Injection Site Irritation"
      ],
      "interventions": [
        {
          "name": "Ice-therapy",
          "type": "OTHER"
        },
        {
          "name": "No Ice-therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2022-04-01",
      "completion_date": "2025-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05269823"
    },
    {
      "nct_id": "NCT02667054",
      "title": "Topical Anesthetic for Procedures Through the Nose",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Drug Reaction to Analgesic Nos"
      ],
      "interventions": [
        {
          "name": "RX0041 4%",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "RX0041 8%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pharmaceutical Project Solutions, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 648,
      "start_date": "2014-09",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 2,
      "location_summary": "Mount Arlington, New Jersey • Columbia, South Carolina",
      "locations": [
        {
          "city": "Mount Arlington",
          "state": "New Jersey"
        },
        {
          "city": "Columbia",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02667054"
    },
    {
      "nct_id": "NCT02596750",
      "title": "The Effect of Microneedle Pretreatment on Topical Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Microneedle Roller",
          "type": "DEVICE"
        },
        {
          "name": "Sham microneedle Roller",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "MALE",
        "summary": "18 Years to 60 Years · Male only"
      },
      "enrollment_count": 21,
      "start_date": "2014-01",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2018-11-27",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02596750"
    },
    {
      "nct_id": "NCT00444756",
      "title": "Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "J-tip jet injection of 1% buffered lidocaine",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Norton Healthcare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "8 Years to 15 Years"
      },
      "enrollment_count": 70,
      "start_date": "2005-04",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2007-03-08",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00444756"
    },
    {
      "nct_id": "NCT01494311",
      "title": "Rapydan Topical Anaesthesia for Arterial Cannulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Arterial Catheterization"
      ],
      "interventions": [
        {
          "name": "Lidocaine/tetracaine patch",
          "type": "DRUG"
        },
        {
          "name": "Placebo Patch",
          "type": "DRUG"
        },
        {
          "name": "Subcutaneous injection of 0.5 ml Lidocain 1%",
          "type": "DRUG"
        },
        {
          "name": "Subcutaneous injection of saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of Vienna",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 90,
      "start_date": "2011-03",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2013-03-18",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01494311"
    },
    {
      "nct_id": "NCT03779659",
      "title": "Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Fear",
        "Anesthesia, Local",
        "Pediatric Dentistry"
      ],
      "interventions": [
        {
          "name": "Synapse TENS device",
          "type": "DEVICE"
        },
        {
          "name": "Topical anesthetic gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "6 Years to 14 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-07",
      "completion_date": "2023-02",
      "has_results": false,
      "last_update_posted_date": "2021-06-08",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03779659"
    },
    {
      "nct_id": "NCT03079713",
      "title": "Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Control During Intravitreal Injections"
      ],
      "interventions": [
        {
          "name": "Handheld vibrator triggered during intravitreal injection for wet ARMD",
          "type": "DEVICE"
        },
        {
          "name": "Normal eye esthesiometry with and without vibration",
          "type": "DEVICE"
        },
        {
          "name": "Handheld vibrator not triggered during intravitreal injection for wet ARMD",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2017-04-12",
      "completion_date": "2019-03-20",
      "has_results": false,
      "last_update_posted_date": "2019-05-09",
      "last_synced_at": "2026-06-27T15:17:01.884Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03079713"
    }
  ]
}