{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Total+Knee+Arthroplasty%3B+Total+Hip+Arthroplasty&page=2",
    "query": {
      "condition": "Total Knee Arthroplasty; Total Hip Arthroplasty",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Total+Knee+Arthroplasty%3B+Total+Hip+Arthroplasty&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T08:46:17.875Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02197273",
      "title": "Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee",
        "Osteoarthritis, Hip",
        "Osteoarthritis, Shoulder"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Standard of care analgesia",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "OhioHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 211,
      "start_date": "2014-07",
      "completion_date": "2015-10",
      "has_results": true,
      "last_update_posted_date": "2016-10-21",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02197273"
    },
    {
      "nct_id": "NCT02241967",
      "title": "Dose Dependent Effects of tDCS on Post-Operative Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Total Knee Arthroplasty (Postoperative Pain)",
        "Total Hip Arthroplasty(Postoperative Pain)"
      ],
      "interventions": [
        {
          "name": "4 Real sessions of Transcranial Direct Current Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "2 Real Sessions of Transcranial Direct Current Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "1 Real Session of Transcranial Direct Current Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham Transcranial Direct Current Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "19 Years to 90 Years"
      },
      "enrollment_count": 119,
      "start_date": "2016-01-07",
      "completion_date": "2020-07-02",
      "has_results": true,
      "last_update_posted_date": "2022-07-13",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02241967"
    },
    {
      "nct_id": "NCT05640336",
      "title": "Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periprosthetic Joint Infection"
      ],
      "interventions": [
        {
          "name": "Single Debridement, Antibiotics and Implant Retention",
          "type": "PROCEDURE"
        },
        {
          "name": "Planned Double Debridement, Antibiotics and Implant Retention",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 490,
      "start_date": "2023-03-03",
      "completion_date": "2032-03",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • Rochester, Minnesota",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05640336"
    },
    {
      "nct_id": "NCT04166539",
      "title": "Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Metallosis",
        "Pain",
        "Total Hip Replacement",
        "Total Knee Replacement"
      ],
      "interventions": [
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Interviews",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Blood draw",
          "type": "OTHER"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "RADIATION"
        },
        {
          "name": "Echocardiogram",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "RADIATION",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 115,
      "start_date": "2019-10-01",
      "completion_date": "2021-09-27",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04166539"
    },
    {
      "nct_id": "NCT02628795",
      "title": "Overcoming TWEAK Signaling to Restore Muscle and Mobility After Joint Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "PRT + FM",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 80,
      "start_date": "2015-10",
      "completion_date": "2021-02-28",
      "has_results": false,
      "last_update_posted_date": "2021-07-07",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02628795"
    },
    {
      "nct_id": "NCT05517278",
      "title": "Clinical Evaluation of the Next Science SurgX Antimicrobial Wound Gel Impact on Surgical Site Complications",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Hip Arthroplasty",
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "SurgX Antimicrobial Wound Gel",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-01",
      "completion_date": "2024-07-15",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 3,
      "location_summary": "Manhasset, New York • New Hyde Park, New York • New York, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        },
        {
          "city": "New Hyde Park",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05517278"
    },
    {
      "nct_id": "NCT01097135",
      "title": "Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Drainage"
      ],
      "interventions": [
        {
          "name": "Duraprep Surgical Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 600,
      "start_date": "2010-03",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2013-09-17",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01097135"
    },
    {
      "nct_id": "NCT01482533",
      "title": "Tissue Culture Versus Swab Culture in Prosthetic Joint Infections",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Revision Total Hip Arthroplasty",
        "Revision Total Knee Arthroplasty"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2011-11-30",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01482533"
    },
    {
      "nct_id": "NCT03166462",
      "title": "Obstructive Sleep Apnea in Elective Orthopaedic Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Apnea, Obstructive",
        "Total Knee Arthroplasty",
        "Total Hip Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Evaluation by Sleep Medicine Specialists",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-02-08",
      "completion_date": "2018-02-08",
      "has_results": false,
      "last_update_posted_date": "2018-03-09",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03166462"
    },
    {
      "nct_id": "NCT03386786",
      "title": "Health Partner Evaluation at Princeton",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty; Total Hip Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Health Partner",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 127,
      "start_date": "2017-06-30",
      "completion_date": "2019-12-11",
      "has_results": false,
      "last_update_posted_date": "2020-01-02",
      "last_synced_at": "2026-07-24T08:46:17.875Z",
      "location_count": 1,
      "location_summary": "Plainsboro, New Jersey",
      "locations": [
        {
          "city": "Plainsboro",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03386786"
    }
  ]
}