{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Total+Knee+Arthroplasty+Recovery",
    "query": {
      "condition": "Total Knee Arthroplasty Recovery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 32,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Total+Knee+Arthroplasty+Recovery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T10:05:10.169Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05981105",
      "title": "Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Opioid Use",
        "Adductor Canal Block",
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "ambIT pump with catheter",
          "type": "DEVICE"
        },
        {
          "name": "ambIT pump with sham catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 64,
      "start_date": "2023-06-12",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05981105"
    },
    {
      "nct_id": "NCT06678750",
      "title": "A Prospective Clinical Study Evaluating the Newton™ TKA Protocol",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "TKA using computer navigation",
          "type": "DEVICE"
        },
        {
          "name": "TKA",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Newton-Wellesley Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-12",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Newton, Massachusetts",
      "locations": [
        {
          "city": "Newton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06678750"
    },
    {
      "nct_id": "NCT03981419",
      "title": "A Study to Evaluate the Effect of GRF6021 on Postoperative Recovery Following Primary Hip or Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Recovery"
      ],
      "interventions": [
        {
          "name": "GRF6021",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Alkahest, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 38,
      "start_date": "2019-07-12",
      "completion_date": "2021-03-04",
      "has_results": true,
      "last_update_posted_date": "2024-03-13",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03981419"
    },
    {
      "nct_id": "NCT01970631",
      "title": "The Study of Physical Activity Rewards After Knee Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Degenerative Joint Disease"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing (MI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Financial Incentives",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 202,
      "start_date": "2014-01-09",
      "completion_date": "2016-11-05",
      "has_results": false,
      "last_update_posted_date": "2018-01-18",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01970631"
    },
    {
      "nct_id": "NCT05113901",
      "title": "Medrol Dosepak Taper for Delayed Post-op Recovery After TKA",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Methylprednisolone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2022-03-03",
      "completion_date": "2022-07-25",
      "has_results": true,
      "last_update_posted_date": "2023-10-23",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05113901"
    },
    {
      "nct_id": "NCT06821269",
      "title": "Functional Recovery After Total Knee Arthroplasty",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthritis Knee"
      ],
      "interventions": [
        {
          "name": "Robotic assisted total knee arthroplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Manual total knee arthroplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Robotic assisted revision total knee arthroplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Manual revision total knee arthroplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-09-01",
      "completion_date": "2027-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-11",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06821269"
    },
    {
      "nct_id": "NCT02740738",
      "title": "Preoperative Pain Threshold and Rapid Recover Programs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Arthritis",
        "Hip Arthritis"
      ],
      "interventions": [
        {
          "name": "Wagner Pain Algometer",
          "type": "DEVICE"
        },
        {
          "name": "Dynamometer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 201,
      "start_date": "2016-03",
      "completion_date": "2018-08-06",
      "has_results": false,
      "last_update_posted_date": "2019-04-08",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02740738"
    },
    {
      "nct_id": "NCT03182933",
      "title": "Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Peripheral Nerve Blockade",
          "type": "DRUG"
        },
        {
          "name": "10 meter walk test on post-operative day 1",
          "type": "BEHAVIORAL"
        },
        {
          "name": "In person and over the phone questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Force transduction of quadriceps strength",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 64,
      "start_date": "2017-05-30",
      "completion_date": "2018-07-16",
      "has_results": true,
      "last_update_posted_date": "2019-06-25",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03182933"
    },
    {
      "nct_id": "NCT02453360",
      "title": "Adductor Canal Block for Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee",
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Adductor Canal Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Adductor Canal Block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2015-05",
      "completion_date": "2017-07",
      "has_results": true,
      "last_update_posted_date": "2019-08-08",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02453360"
    },
    {
      "nct_id": "NCT01826305",
      "title": "Independent Exercise Compared With Formal Rehabilitation Following Primary Total Knee Replacement",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Recovery Following Primary Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Formal Rehabilitation Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Independent Exercise Cohort",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2014-07",
      "completion_date": "2015-10-23",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-06-26T10:05:10.169Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01826305"
    }
  ]
}