{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Total+Parenteral+Nutrition-induced+Cholestasis",
    "query": {
      "condition": "Total Parenteral Nutrition-induced Cholestasis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Total+Parenteral+Nutrition-induced+Cholestasis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T04:51:45.663Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02328768",
      "title": "Compassionate Use of Omegaven® for the Treatment of Intestinal Failure Associated Liver Disease in Children",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Total Parenteral Nutrition-Induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2024-01-09",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02328768"
    },
    {
      "nct_id": "NCT02721277",
      "title": "SMOFlipid to Lessen the Severity of Neonatal Cholestasis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cholestasis",
        "Jaundice, Obstructive"
      ],
      "interventions": [
        {
          "name": "SMOFlipid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "23 Weeks to 1 Year"
      },
      "enrollment_count": 2,
      "start_date": "2016-05",
      "completion_date": "2017-02-02",
      "has_results": true,
      "last_update_posted_date": "2017-04-17",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02721277"
    },
    {
      "nct_id": "NCT00826020",
      "title": "Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Parenteral Nutrition Associated Liver Disease PNALD",
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven™",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2009-05-01",
      "completion_date": "2017-10-06",
      "has_results": true,
      "last_update_posted_date": "2023-10-05",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00826020"
    },
    {
      "nct_id": "NCT01845116",
      "title": "Omegaven® in the Treatment of Parenteral Nutrition (PN) Induced Liver Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Weeks",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "4 Weeks to 18 Years"
      },
      "enrollment_count": 11,
      "start_date": "2010-07",
      "completion_date": "2020-07",
      "has_results": true,
      "last_update_posted_date": "2022-11-23",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01845116"
    },
    {
      "nct_id": "NCT01323907",
      "title": "Compassionate Use of Omegaven IV Fat Emulsion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven IV lipid emulsion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sivan Kinberg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Months to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2011-01",
      "completion_date": "2019-02-13",
      "has_results": false,
      "last_update_posted_date": "2020-02-06",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01323907"
    },
    {
      "nct_id": "NCT02534077",
      "title": "Intravenous Fat Emulsion Comprised of Fish Oil in the Treatment of Parenteral Nutrition Induced Liver Injury in Infants",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Days",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "14 Days to 2 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2024-07-26",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02534077"
    },
    {
      "nct_id": "NCT00816348",
      "title": "Compassionate Use of Omegaven IV Fat Emulsion",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cholestasis",
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cindy Haller",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Weeks",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "2 Weeks to 5 Years"
      },
      "enrollment_count": 15,
      "start_date": "2008-12",
      "completion_date": "2014-02",
      "has_results": true,
      "last_update_posted_date": "2017-03-10",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 2,
      "location_summary": "Manhasset, New York • New Hyde Park, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        },
        {
          "city": "New Hyde Park",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00816348"
    },
    {
      "nct_id": "NCT02370251",
      "title": "Compassionate Use of Omegaven in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis",
        "Cholestasis",
        "Short Bowel Syndrome",
        "Gastroschisis",
        "Intestinal Atresia",
        "Infant, Premature, Diseases",
        "Cholestasis of Parenteral Nutrition"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 63,
      "start_date": "2015-06",
      "completion_date": "2019-09-27",
      "has_results": true,
      "last_update_posted_date": "2019-11-25",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02370251"
    },
    {
      "nct_id": "NCT02780193",
      "title": "Intravenous Fish Oils in the Treatment of Parenteral Nutrition Liver Injury",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Cholestasis",
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2019-04-08",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02780193"
    },
    {
      "nct_id": "NCT01412359",
      "title": "Compassionate Use of Omegaven® in the Treatment of Parenteral Nutrition Associated Hepatic Injury",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jeffrey Rudolph",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "2 Months to 10 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2019-04-24",
      "last_synced_at": "2026-07-22T04:51:45.663Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01412359"
    }
  ]
}