{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Transposition+of+Great+Vessels",
    "query": {
      "condition": "Transposition of Great Vessels"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Transposition+of+Great+Vessels&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:45:57.195Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06932081",
      "title": "Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Adult Congenital Heart Disease",
        "Congenital Heart Disease",
        "Systemic Right Ventricle",
        "Transposition of the Great Arteries",
        "Congenitally Corrected Transposition of the Great Arteries",
        "Fontan",
        "Single Ventricle",
        "Tetralogy of Fallot (TOF)"
      ],
      "interventions": [
        {
          "name": "SGLT2 inhibitors",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Leiden University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2023-01-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • Grand Rapids, Michigan • New York, New York",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06932081"
    },
    {
      "nct_id": "NCT00374088",
      "title": "N-Acetylcysteine in Neonatal Congenital Heart Surgery (INACT Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Transposition of Great Vessels",
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "Up to 3 Months"
      },
      "enrollment_count": 21,
      "start_date": "2005-02",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2012-01-19",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00374088"
    },
    {
      "nct_id": "NCT00497705",
      "title": "Genes Causing Ebstein's Anomaly",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Septal Defects, Ventricle",
        "Heart Defects, Congenital",
        "Double Outlet Right Ventricle",
        "Truncus Arteriosus, Persistent"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": null,
      "start_date": "2007-07-03",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00497705"
    },
    {
      "nct_id": "NCT00972608",
      "title": "Surgical Planning for Reconstruction of Complex Heart Defects",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Double Outlet Right Ventricle"
      ],
      "interventions": [
        {
          "name": "Anatomic Reconstruction and Surgical Planning",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "Up to 22 Years"
      },
      "enrollment_count": 66,
      "start_date": "2009-08",
      "completion_date": "2019-01-09",
      "has_results": false,
      "last_update_posted_date": "2022-01-11",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00972608"
    },
    {
      "nct_id": "NCT04788082",
      "title": "Clinical Impact of Rapid Prototyping 3D Models for Surgical Management",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Double Outlet Right Ventricle",
        "Transposition of the Great Arteries",
        "Truncus Arteriosus",
        "Congenitally Corrected Transposition of the Great Arteries"
      ],
      "interventions": [
        {
          "name": "3D Printed Heart Model",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2017-05-01",
      "completion_date": "2021-06",
      "has_results": false,
      "last_update_posted_date": "2021-03-09",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • Washington D.C., District of Columbia • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04788082"
    },
    {
      "nct_id": "NCT00006183",
      "title": "Comparison of Hematocrit Levels in Infant Heart Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Heart Diseases",
        "Heart Defects, Congenital",
        "Transposition of Great Vessels"
      ],
      "interventions": [
        {
          "name": "Cardiopulmonary Bypass with Two Different Intra-Operative Hematocrits",
          "type": "PROCEDURE"
        },
        {
          "name": "Thoracic Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 120,
      "start_date": "2000-07",
      "completion_date": "2005-07",
      "has_results": false,
      "last_update_posted_date": "2016-07-29",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006183"
    },
    {
      "nct_id": "NCT01971593",
      "title": "The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tetralogy of Fallot",
        "Transposition of the Great Vessels With an Arterial Switch",
        "Single Ventricle With a Fontan Palliation"
      ],
      "interventions": [
        {
          "name": "Eplerenone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 26,
      "start_date": "2013-08",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2018-05-04",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01971593"
    },
    {
      "nct_id": "NCT02184169",
      "title": "Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transposition of the Great Vessels",
        "Hypoplastic Left Heart Syndrome",
        "Oxygen Consumption Based Assessment of Hemodynamics"
      ],
      "interventions": [
        {
          "name": "General Electric Healthcare E-COVX Gas Monitoring Module for VO2 Measurments",
          "type": "DEVICE"
        },
        {
          "name": "Edwards Continuous SVO2 Catheter and Monitoring System - 4.5 fr",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "1 Day to 6 Months"
      },
      "enrollment_count": 27,
      "start_date": "2012-12",
      "completion_date": "2019-01-29",
      "has_results": true,
      "last_update_posted_date": "2020-06-04",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02184169"
    },
    {
      "nct_id": "NCT04713657",
      "title": "Beta-blocker Administration for Cardiomyocyte Division",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tetralogy of Fallot",
        "Double Outlet Right Ventricle"
      ],
      "interventions": [
        {
          "name": "N-thymidine",
          "type": "OTHER"
        },
        {
          "name": "Urine Collection",
          "type": "OTHER"
        },
        {
          "name": "Echocardiogram",
          "type": "PROCEDURE"
        },
        {
          "name": "Cardiac MRI (CMR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Propranolol Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Physical Exam",
          "type": "PROCEDURE"
        },
        {
          "name": "Specimen Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "60 Days",
        "sex": "ALL",
        "summary": "30 Days to 60 Days"
      },
      "enrollment_count": 40,
      "start_date": "2022-12-16",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-18",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 3,
      "location_summary": "New York, New York • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04713657"
    },
    {
      "nct_id": "NCT03073122",
      "title": "The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transposition Great Arteries",
        "Executive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Brain MRI, neurocognitive and psychological testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Years",
        "maximum_age": "33 Years",
        "sex": "ALL",
        "summary": "24 Years to 33 Years"
      },
      "enrollment_count": 127,
      "start_date": "2017-11-09",
      "completion_date": "2023-01-31",
      "has_results": false,
      "last_update_posted_date": "2023-08-16",
      "last_synced_at": "2026-05-22T08:45:57.195Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03073122"
    }
  ]
}