{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Transtibial+Amputation+-+Unilateral",
    "query": {
      "condition": "Transtibial Amputation - Unilateral"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T10:10:58.153Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05964855",
      "title": "Comparison of Various Prosthetic Foot-Ankle Mechanisms",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transtibial Amputation - Unilateral"
      ],
      "interventions": [
        {
          "name": "MIT Variable Stiffness Prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "MIT Variable Equilibrium Angle Prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "MIT Sliding Beam Passive Prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "Ossur Pro-flex XC",
          "type": "DEVICE"
        },
        {
          "name": "Blatchford Elan Variable-Dampening Prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2023-07-28",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-13",
      "last_synced_at": "2026-07-23T10:10:58.153Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05964855"
    },
    {
      "nct_id": "NCT03722797",
      "title": "Physical Activity in Adults With Amputation",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputees"
      ],
      "interventions": [
        {
          "name": "Metabolic Cost Testing Procedures",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Delaware",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 3,
      "start_date": "2017-05-11",
      "completion_date": "2022-02-17",
      "has_results": false,
      "last_update_posted_date": "2022-03-04",
      "last_synced_at": "2026-07-23T10:10:58.153Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03722797"
    },
    {
      "nct_id": "NCT03446131",
      "title": "Improved Training Program for Fall Prevention of War Fighters",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Limb Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 45,
      "start_date": "2018-03-12",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-01-07",
      "last_synced_at": "2026-07-23T10:10:58.153Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Bethesda, Maryland • Rochester, Minnesota + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03446131"
    },
    {
      "nct_id": "NCT04431817",
      "title": "KinetiGait- Analysis of Depth Camera to Assist Gait Analysis for Unilateral Transtibial/Transfemoral Amputees",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lower Limb Amputation"
      ],
      "interventions": [
        {
          "name": "KinetiGait",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 41,
      "start_date": "2021-08-01",
      "completion_date": "2023-03-28",
      "has_results": false,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-07-23T10:10:58.153Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04431817"
    },
    {
      "nct_id": "NCT02864693",
      "title": "Comparative Effectiveness of Microprocessor Controlled and Carbon Fiber Prosthetic Feet in Transtibial Amputees",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Kinnex",
          "type": "DEVICE"
        },
        {
          "name": "Pacifica LP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ability Prosthetics and Orthotics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 30,
      "start_date": "2016-06",
      "completion_date": "2018-04",
      "has_results": false,
      "last_update_posted_date": "2018-07-10",
      "last_synced_at": "2026-07-23T10:10:58.153Z",
      "location_count": 3,
      "location_summary": "Hagerstown, Maryland • Charlotte, North Carolina • York, Pennsylvania",
      "locations": [
        {
          "city": "Hagerstown",
          "state": "Maryland"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02864693"
    },
    {
      "nct_id": "NCT02542761",
      "title": "Comparative Performance of Dynamic Elastic Response Feet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transtibial Amputation - Unilateral"
      ],
      "interventions": [
        {
          "name": "Fiberglass Composite foot",
          "type": "DEVICE"
        },
        {
          "name": "Carbon Fiber Composite Foot",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2015-06",
      "completion_date": "2016-05",
      "has_results": true,
      "last_update_posted_date": "2018-09-20",
      "last_synced_at": "2026-07-23T10:10:58.153Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02542761"
    },
    {
      "nct_id": "NCT07263945",
      "title": "Influence of Prosthetic Foot Stiffness on Transtibial Osseointegrated Bone-Anchored Limb Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Amputation",
        "Transtibial Amputation - Unilateral",
        "Bone Anchored Devices",
        "Osseointegration"
      ],
      "interventions": [
        {
          "name": "As-prescribed prosthetic foot stiffness",
          "type": "DEVICE"
        },
        {
          "name": "A prosthetic foot that is two prosthetic foot stiffness categories stiffer than the stiffness of the as-prescribed prosthetic foot",
          "type": "DEVICE"
        },
        {
          "name": "A prosthetic foot that is two prosthetic foot stiffness categories softer than the stiffness of the as-prescribed prosthetic foot",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-11-25",
      "completion_date": "2030-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-07-23T10:10:58.153Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07263945"
    }
  ]
}