{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Traumatic+Arthritis+of+Knee",
    "query": {
      "condition": "Traumatic Arthritis of Knee"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 40,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Traumatic+Arthritis+of+Knee&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:05:17.815Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00698854",
      "title": "A Clinical Investigation of the Vanguard™ Complete Knee System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Traumatic Arthritis",
        "Rheumatoid Arthritis",
        "Lower Limb Deformity",
        "Complications, Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Vanguard™ Complete Knee System",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard™ Patient-Specific Femur",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 552,
      "start_date": "2004-03",
      "completion_date": "2024-03",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 8,
      "location_summary": "Cedar Rapids, Iowa • Rockville, Maryland • Cape Girardeau, Missouri + 5 more",
      "locations": [
        {
          "city": "Cedar Rapids",
          "state": "Iowa"
        },
        {
          "city": "Rockville",
          "state": "Maryland"
        },
        {
          "city": "Cape Girardeau",
          "state": "Missouri"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Grapevine",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00698854"
    },
    {
      "nct_id": "NCT04145401",
      "title": "Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Revision Knee implants",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroPort Orthopedics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2020-09-30",
      "completion_date": "2033-11-01",
      "has_results": false,
      "last_update_posted_date": "2024-03-20",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 1,
      "location_summary": "Englewood, Colorado",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04145401"
    },
    {
      "nct_id": "NCT00289107",
      "title": "Randomized Fixed Bearing vs Mobile Bearing Cruciate Substituting TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Other Inflammatory Arthritis",
        "Post-Traumatic Arthritis",
        "Juvenile Rheumatoid Arthritis",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Total Knee Arthroplasty",
          "type": "DEVICE"
        },
        {
          "name": "Total knee replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 149,
      "start_date": "2001-04-01",
      "completion_date": "2007-11-01",
      "has_results": true,
      "last_update_posted_date": "2023-05-03",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 3,
      "location_summary": "Greensboro, North Carolina • Austin, Texas • Lakewood, Washington",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Lakewood",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00289107"
    },
    {
      "nct_id": "NCT00589485",
      "title": "Total Knee Replacement Using Simplex® or Cobalt™ Bone Cement",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Traumatic Arthritis",
        "Knee Arthritis"
      ],
      "interventions": [
        {
          "name": "Simplex® Bone Cement",
          "type": "DEVICE"
        },
        {
          "name": "Cobalt™ Bone Cement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2006-11",
      "completion_date": "2006-11",
      "has_results": false,
      "last_update_posted_date": "2017-06-21",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 1,
      "location_summary": "Warsaw, Indiana",
      "locations": [
        {
          "city": "Warsaw",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00589485"
    },
    {
      "nct_id": "NCT01542580",
      "title": "A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Traumatic Arthritis",
        "Post Traumatic Deformity",
        "Complications; Arthroplasty",
        "Deformity of Limb"
      ],
      "interventions": [
        {
          "name": "Vanguard SSK 360 with PS Bearing",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard SSK 360 with PSC bearing",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard DA 360",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard 360 TiNbN Femur with PS bearing",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard 360 TiNbN Femur with PSC bearing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 255,
      "start_date": "2012-03",
      "completion_date": "2031-12",
      "has_results": false,
      "last_update_posted_date": "2025-11-25",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 4,
      "location_summary": "Morton Grove, Illinois • Henderson, Nevada • Salt Lake City, Utah + 1 more",
      "locations": [
        {
          "city": "Morton Grove",
          "state": "Illinois"
        },
        {
          "city": "Henderson",
          "state": "Nevada"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01542580"
    },
    {
      "nct_id": "NCT07286513",
      "title": "Persona SoluTion PPS Femur PMCF",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rhematoid Arthritis",
        "Osteo Arthritis of the Knee",
        "Traumatic Arthritis of Knee (Diagnosis)",
        "Polyarthritis",
        "Collagen Disorders",
        "Avascular Necrosis of Femoral Condyle",
        "Valgus Deformity",
        "Varus Deformity",
        "Flexion Deformity of Knee"
      ],
      "interventions": [
        {
          "name": "Total knee arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2026-02-26",
      "completion_date": "2037-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07286513"
    },
    {
      "nct_id": "NCT02468583",
      "title": "Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Traumatic Osteoarthritis of the Knee",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post-traumatic Osteoarthritis of the Knee"
      ],
      "interventions": [
        {
          "name": "FX006 32 mg",
          "type": "DRUG"
        },
        {
          "name": "TCA IR 40 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pacira Pharmaceuticals, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 6,
      "start_date": "2015-02",
      "completion_date": "2016-07",
      "has_results": true,
      "last_update_posted_date": "2024-01-24",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02468583"
    },
    {
      "nct_id": "NCT00966979",
      "title": "Triathlon® Partial Knee Replacement (PKR) Outcomes Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee"
      ],
      "interventions": [
        {
          "name": "Triathlon PKR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 111,
      "start_date": "2010-01",
      "completion_date": "2023-05",
      "has_results": true,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 6,
      "location_summary": "Jacksonville, Florida • Egg Harbor, New Jersey • Buffalo, New York + 3 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Egg Harbor",
          "state": "New Jersey"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Media",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00966979"
    },
    {
      "nct_id": "NCT00764894",
      "title": "Foundation Knee Study - Retrospective",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Post-traumatic Arthritis",
        "Inflammatory Tissue Disorders",
        "Arthritis Secondary to Other Diseases",
        "Avascular Necrosis of the Femoral Condyles"
      ],
      "interventions": [
        {
          "name": "Foundation Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2007-10",
      "completion_date": "2011-02",
      "has_results": false,
      "last_update_posted_date": "2011-02-09",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 1,
      "location_summary": "Vero Beach, Florida",
      "locations": [
        {
          "city": "Vero Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00764894"
    },
    {
      "nct_id": "NCT02574312",
      "title": "ATTUNE Single-Use Instrumentation vs. ATTUNE Reusable Instrumentation in Primary Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Post-traumatic Arthritis"
      ],
      "interventions": [
        {
          "name": "ATTUNE TKA with ATTUNE RUI",
          "type": "DEVICE"
        },
        {
          "name": "ATTUNE TKA with ATTUNE SUI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 88,
      "start_date": "2015-10-01",
      "completion_date": "2019-03-28",
      "has_results": true,
      "last_update_posted_date": "2020-04-09",
      "last_synced_at": "2026-05-22T09:05:17.815Z",
      "location_count": 2,
      "location_summary": "La Jolla, California • Wilkes-Barre, Pennsylvania",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Wilkes-Barre",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02574312"
    }
  ]
}