{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tricuspid+Regurgitation&page=2",
    "query": {
      "condition": "Tricuspid Regurgitation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Tricuspid+Regurgitation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:11:20.923Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04221490",
      "title": "2019-06 TRISCEND Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tricuspid Valve Regurgitation",
        "Heart Valve Diseases",
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Transcatheter Tricuspid Valve Replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 228,
      "start_date": "2020-05-06",
      "completion_date": "2029-01-31",
      "has_results": true,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 14,
      "location_summary": "Los Angeles, California • Stanford, California • Atlanta, Georgia + 9 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04221490"
    },
    {
      "nct_id": "NCT03745313",
      "title": "Edwards CLASP TR EFS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tricuspid Regurgitation"
      ],
      "interventions": [
        {
          "name": "Edwards PASCAL Transcatheter Valve Repair System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2019-02-05",
      "completion_date": "2025-05-13",
      "has_results": true,
      "last_update_posted_date": "2025-09-29",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 15,
      "location_summary": "Los Angeles, California • Atlanta, Georgia • Chicago, Illinois + 11 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03745313"
    },
    {
      "nct_id": "NCT06229886",
      "title": "Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tricuspid Regurgitation",
        "Mechanical Ventilation Pressure High",
        "Pediatric Respiratory Diseases"
      ],
      "interventions": [
        {
          "name": "Application of positive-end-expiratory pressure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Months to 18 Years"
      },
      "enrollment_count": 20,
      "start_date": "2023-12-06",
      "completion_date": "2024-09-21",
      "has_results": false,
      "last_update_posted_date": "2024-09-26",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 1,
      "location_summary": "New Hyde Park, New York",
      "locations": [
        {
          "city": "New Hyde Park",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06229886"
    },
    {
      "nct_id": "NCT06137807",
      "title": "TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tricuspid Regurgitation",
        "Tricuspid Valve Disease"
      ],
      "interventions": [
        {
          "name": "TricValve® Transcatheter Bicaval Valve System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "P+F Products + Features USA Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-07-23",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2025-06-08",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 36,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • San Diego, California + 31 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Delray Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06137807"
    },
    {
      "nct_id": "NCT05357404",
      "title": "Age and Sex-Specific PREValence of AcqUirEd VALVular Heart DiseasE",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Valvular Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cardiovascular Research Foundation, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 2870,
      "start_date": "2022-04-21",
      "completion_date": "2025-04",
      "has_results": false,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 1,
      "location_summary": "Walnut Creek, California",
      "locations": [
        {
          "city": "Walnut Creek",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05357404"
    },
    {
      "nct_id": "NCT05006443",
      "title": "Staging Classification of Severe Tricuspid Regurgitation Using Novel Cardiac Imaging Techniques",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tricuspid Regurgitation"
      ],
      "interventions": [
        {
          "name": "Cardiac Magnetic Resonance",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 75,
      "start_date": "2022-01-14",
      "completion_date": "2025-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05006443"
    },
    {
      "nct_id": "NCT07586995",
      "title": "A Post-Market Assessment of the Safety and Performance of the TriClip™ System",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tricuspid Regurgitation (TR)"
      ],
      "interventions": [
        {
          "name": "Tricuspid Transcatheter Edge-to-Edge Repair (TEER)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2026-06",
      "completion_date": "2033-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 2,
      "location_summary": "La Jolla, California • Chicago, Illinois",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07586995"
    },
    {
      "nct_id": "NCT05453526",
      "title": "The Bronx-Valve Registry",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Valvular Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 330570,
      "start_date": "2010-01-01",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-03",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05453526"
    },
    {
      "nct_id": "NCT00665301",
      "title": "Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congestive Heart Failure",
        "Ischemic Cardiomyopathy",
        "Mitral Valve Prolapse",
        "Mitral Regurgitation",
        "Aortic Valve Disease",
        "Tricuspid Regurgitation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Woolsthorpe Technologies, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 54,
      "start_date": "2008-03",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2008-07-08",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 3,
      "location_summary": "Nashville, Tennessee • Houston, Texas",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00665301"
    },
    {
      "nct_id": "NCT05848284",
      "title": "Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tricuspid Regurgitation",
        "Tricuspid Valve Disease",
        "Tricuspid Valvular Disorders"
      ],
      "interventions": [
        {
          "name": "VDyne Transcatheter Tricuspid Valve Replacement System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VDyne, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-04-01",
      "completion_date": "2031-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-05-22T09:11:20.923Z",
      "location_count": 10,
      "location_summary": "Los Angeles, California • Detriot, Michigan • Minneapolis, Minnesota + 7 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Detriot",
          "state": "Michigan"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05848284"
    }
  ]
}