{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Twin%3B+Complicating+Pregnancy",
    "query": {
      "condition": "Twin; Complicating Pregnancy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Twin%3B+Complicating+Pregnancy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T01:45:41.390Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06056635",
      "title": "A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fetal Conditions",
        "Maternal; Procedure",
        "Pregnancy Related",
        "Twin to Twin Transfusion Syndrome",
        "In Utero Procedure Affecting Fetus or Newborn",
        "Chorion; Abnormal",
        "Twin Reversal Arterial Perfusion Syndrome",
        "Twin Monochorionic Monoamniotic Placenta",
        "Chorioangioma",
        "Vasa Previa"
      ],
      "interventions": [
        {
          "name": "Karl Storz Curved Scope",
          "type": "DEVICE"
        },
        {
          "name": "Karl Storz Straight Scope",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2024-08-15",
      "completion_date": "2027-05-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-25",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06056635"
    },
    {
      "nct_id": "NCT01812239",
      "title": "Vaginal Progesterone in Twins With Short Cervix",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "Vaginal Progesterone gel.",
          "type": "DRUG"
        },
        {
          "name": "fetal fibronectin swab.",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Obstetrix Medical Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2014-03",
      "completion_date": "2018-08",
      "has_results": false,
      "last_update_posted_date": "2014-12-19",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 1,
      "location_summary": "San Jose, California",
      "locations": [
        {
          "city": "San Jose",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01812239"
    },
    {
      "nct_id": "NCT00341731",
      "title": "Environmental Factors in the Development of Polycystic Ovary Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Polycystic Ovary Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Environmental Health Sciences (NIEHS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": null,
      "start_date": "2000-12",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2009-12-01",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 2,
      "location_summary": "Research Triangle Park, North Carolina • Richmond, Virginia",
      "locations": [
        {
          "city": "Research Triangle Park",
          "state": "North Carolina"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00341731"
    },
    {
      "nct_id": "NCT00156000",
      "title": "fFN & E3 in the Prediction of PTB in Women With Twin Pregnancies Receiving 17OHP or Placebo",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preterm Delivery",
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Fetal Fibronectin",
          "type": "DEVICE"
        },
        {
          "name": "Salivary Estriol",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Obstetrix Medical Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2005-08",
      "completion_date": "2006-02",
      "has_results": false,
      "last_update_posted_date": "2014-12-19",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 2,
      "location_summary": "Mesa, Arizona • Phoenix, Arizona",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00156000"
    },
    {
      "nct_id": "NCT05772156",
      "title": "Prophylactic Methylergonovine for Twin Cesarean",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Twin; Complicating Pregnancy",
        "Postpartum Hemorrhage"
      ],
      "interventions": [
        {
          "name": "Methylergonovine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "Up to 65 Years · Female only"
      },
      "enrollment_count": 66,
      "start_date": "2023-03-07",
      "completion_date": "2024-03-11",
      "has_results": true,
      "last_update_posted_date": "2025-06-13",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05772156"
    },
    {
      "nct_id": "NCT02490384",
      "title": "Physical Exam Indicated Cerclage in Twin Gestations",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin Pregnancy, Antepartum Condition or Complication",
        "Preterm Birth",
        "Cervical Dilation Premature"
      ],
      "interventions": [
        {
          "name": "Physical exam indicated cerclage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2015-06",
      "completion_date": "2019-12-12",
      "has_results": false,
      "last_update_posted_date": "2020-04-27",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 7,
      "location_summary": "Washington D.C., District of Columbia • Albany, New York • New York, New York + 4 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Albany",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Dayton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02490384"
    },
    {
      "nct_id": "NCT00163020",
      "title": "17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "17-alpha-hydroxyprogesterone caproate injectable",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Obstetrix Medical Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 321,
      "start_date": "2004-11",
      "completion_date": "2009-08",
      "has_results": true,
      "last_update_posted_date": "2016-04-11",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 18,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Laguna Hills, California + 13 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00163020"
    },
    {
      "nct_id": "NCT01177553",
      "title": "Randomized Clinical Trial: Expectant Management vs Laser Treatment of Monochorionic Twins With Severe Selective Intrauterine Growth Retardation and Absent or Reverse Diastolic Flow in the Umbilical Artery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intrauterine Growth Retardation"
      ],
      "interventions": [
        {
          "name": "selective laser photocoagulation of communicating vessels",
          "type": "PROCEDURE"
        },
        {
          "name": "Expected Management",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 5,
      "start_date": "2007-05",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2013-02-21",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Tampa, Florida",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01177553"
    },
    {
      "nct_id": "NCT00099164",
      "title": "Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Preterm Birth",
        "Pregnancy",
        "Multifetal"
      ],
      "interventions": [
        {
          "name": "17 alpha-hydroxyprogesterone caproate (17P)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The George Washington University Biostatistics Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 795,
      "start_date": "2004-04",
      "completion_date": "2007-09",
      "has_results": false,
      "last_update_posted_date": "2019-02-21",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 14,
      "location_summary": "Birmingham, Alabama • Chicago, Illinois • Detroit, Michigan + 11 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00099164"
    },
    {
      "nct_id": "NCT03775954",
      "title": "Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "High Risk Pregnancy",
        "Congenital Heart Disease",
        "Fetal Hydrops",
        "Twin Monochorionic Monoamniotic Placenta",
        "Gastroschisis",
        "Fetal Demise",
        "Stillbirth",
        "Fetal Arrhythmia",
        "Long QT Syndrome",
        "Intrauterine Fetal Death",
        "Sudden Infant Death",
        "Pregnancy Loss",
        "Twin Twin Transfusion Syndrome",
        "Birth Defect",
        "Fetal Cardiac Anomaly",
        "Fetal Cardiac Disorder",
        "Fetal Death",
        "Brugada Syndrome",
        "Fetal Tachycardia"
      ],
      "interventions": [
        {
          "name": "Fetal Magnetocardiogram and Neonatal Electrocardiogram",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Substudy only: Maternal/Infant Pharmacogenomic assessment postnatally",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "GENETIC"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2018-07-01",
      "completion_date": "2028-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-04",
      "last_synced_at": "2026-05-22T01:45:41.390Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03775954"
    }
  ]
}