{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Twin+Diseases",
    "query": {
      "condition": "Twin Diseases"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 75,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Twin+Diseases&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T01:26:35.603Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00001246",
      "title": "Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Attention Deficit Hyperactivity Disorder",
        "Schizophrenia",
        "Attention Deficit Disorder With Hyperactivity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "3 Years to 120 Years"
      },
      "enrollment_count": 4274,
      "start_date": "1990-06-19",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001246"
    },
    {
      "nct_id": "NCT04140669",
      "title": "Automated Myocardial Performance Index Using Samsung HERA W10",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin to Twin Transfusion Syndrome",
        "Congenital Diaphragmatic Hernia",
        "Neural Tube Defects",
        "Lower Urinary Tract Infection"
      ],
      "interventions": [
        {
          "name": "Automated Myocardial Performance Index (MPI)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 7,
      "start_date": "2019-09-16",
      "completion_date": "2020-07-07",
      "has_results": false,
      "last_update_posted_date": "2022-07-13",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04140669"
    },
    {
      "nct_id": "NCT07223684",
      "title": "TDAP in Burn Patients (Group 2)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis",
        "Burn Injury",
        "Wound Healing",
        "Critical Illness",
        "Multiple Organ Dysfunction Syndrome"
      ],
      "interventions": [
        {
          "name": "Observational Cohort (No Intervention)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 80,
      "start_date": "2026-05-15",
      "completion_date": "2027-12-15",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 3,
      "location_summary": "Tampa, Florida • Atlanta, Georgia • Houston, Texas",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223684"
    },
    {
      "nct_id": "NCT05181449",
      "title": "Randomized Controlled Trial of Digital Twin Precision Treatment: A Novel Whole Body Digital Twin Enabled Precision Treatment for Type 2 Diabetes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Twin Precision Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 150,
      "start_date": "2022-02-01",
      "completion_date": "2026-11-29",
      "has_results": false,
      "last_update_posted_date": "2025-09-18",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 1,
      "location_summary": "Twinsburg, Ohio",
      "locations": [
        {
          "city": "Twinsburg",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05181449"
    },
    {
      "nct_id": "NCT01054872",
      "title": "Examining the Role of Genetics in Determining the Immune Response to an HIV Vaccine in HIV-Uninfected Adult Twins",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "HIV-1 DNA plasmid vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "HIV-1 recombinant Ad5 vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 8,
      "start_date": "2010-01",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2021-10-15",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Seattle, Washington",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01054872"
    },
    {
      "nct_id": "NCT02249624",
      "title": "The Utility of MRI Scoring to Predict Neurodevelopmental Outcomes in Survivors of Twin-to-Twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fetofetal Transfusion"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Catherine Cibulskis, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Years",
        "sex": "ALL",
        "summary": "Up to 3 Years"
      },
      "enrollment_count": 51,
      "start_date": "2014-09",
      "completion_date": "2024-05-30",
      "has_results": false,
      "last_update_posted_date": "2024-06-24",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02249624"
    },
    {
      "nct_id": "NCT06084247",
      "title": "The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin to Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Curved KARL STORZ fetoscope",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Scopes",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jimmy Espinoza",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 160,
      "start_date": "2025-09-01",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06084247"
    },
    {
      "nct_id": "NCT00638885",
      "title": "Memory and the Hippocampus in Twins",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PTSD",
        "Stress Disorders, Post-Traumatic"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "MALE",
        "summary": "50 Years to 70 Years · Male only"
      },
      "enrollment_count": 142,
      "start_date": "2010-04",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2015-01-15",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 1,
      "location_summary": "Decatur, Georgia",
      "locations": [
        {
          "city": "Decatur",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00638885"
    },
    {
      "nct_id": "NCT02506049",
      "title": "Laser Photocoagulation in Twin to Twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin to Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "S-LPC:Selective Laser Photocoagulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Weeks",
        "maximum_age": "27 Weeks",
        "sex": "FEMALE",
        "summary": "16 Weeks to 27 Weeks · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2010-04",
      "completion_date": "2020-10-28",
      "has_results": false,
      "last_update_posted_date": "2020-11-13",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 2,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02506049"
    },
    {
      "nct_id": "NCT01879696",
      "title": "Double Blinded, Randomized Clinical Trial of the Twin Star ECSPRESS Monitoring System for the Reduction of the Incidence of Fasciotomy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Compartment Syndrome"
      ],
      "interventions": [
        {
          "name": "ECSPRESS catheter with active vacuum",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Twin Star Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "ALL",
        "summary": "18 Years to 44 Years"
      },
      "enrollment_count": 150,
      "start_date": "2013-06",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2013-06-18",
      "last_synced_at": "2026-07-22T01:26:35.603Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01879696"
    }
  ]
}