{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Twin+Twin+Transfusion+Syndrome",
    "query": {
      "condition": "Twin Twin Transfusion Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Twin+Twin+Transfusion+Syndrome&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:49:23.738Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06056635",
      "title": "A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fetal Conditions",
        "Maternal; Procedure",
        "Pregnancy Related",
        "Twin to Twin Transfusion Syndrome",
        "In Utero Procedure Affecting Fetus or Newborn",
        "Chorion; Abnormal",
        "Twin Reversal Arterial Perfusion Syndrome",
        "Twin Monochorionic Monoamniotic Placenta",
        "Chorioangioma",
        "Vasa Previa"
      ],
      "interventions": [
        {
          "name": "Karl Storz Curved Scope",
          "type": "DEVICE"
        },
        {
          "name": "Karl Storz Straight Scope",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2024-08-15",
      "completion_date": "2027-05-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-25",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06056635"
    },
    {
      "nct_id": "NCT05008744",
      "title": "Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin to Twin Transfusion as Antepartum Condition",
        "Monochorionic Diamniotic Placenta"
      ],
      "interventions": [
        {
          "name": "Fetoscopic laser ablation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 2000,
      "start_date": "2021-10-01",
      "completion_date": "2031-10-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-19",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05008744"
    },
    {
      "nct_id": "NCT06991400",
      "title": "Evaluation of Laparotomy With Trans-Amniotic Suture Placement in TTTS Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin to Twin Transfusion Syndrome",
        "Twin Anemia-Polycythemia Sequence"
      ],
      "interventions": [
        {
          "name": "Trans-Amniotic Suture Placement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 34,
      "start_date": "2024-11-01",
      "completion_date": "2026-06-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-28",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06991400"
    },
    {
      "nct_id": "NCT01622049",
      "title": "Selective Laser Photocoagulation of Communicating Vessels in Twin-Twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Selective Laser Photocoagulation of Communicating Vessels",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 77,
      "start_date": "2006-10",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2013-03-14",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01622049"
    },
    {
      "nct_id": "NCT04140669",
      "title": "Automated Myocardial Performance Index Using Samsung HERA W10",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin to Twin Transfusion Syndrome",
        "Congenital Diaphragmatic Hernia",
        "Neural Tube Defects",
        "Lower Urinary Tract Infection"
      ],
      "interventions": [
        {
          "name": "Automated Myocardial Performance Index (MPI)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 7,
      "start_date": "2019-09-16",
      "completion_date": "2020-07-07",
      "has_results": false,
      "last_update_posted_date": "2022-07-13",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04140669"
    },
    {
      "nct_id": "NCT02506049",
      "title": "Laser Photocoagulation in Twin to Twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin to Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "S-LPC:Selective Laser Photocoagulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Weeks",
        "maximum_age": "27 Weeks",
        "sex": "FEMALE",
        "summary": "16 Weeks to 27 Weeks · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2010-04",
      "completion_date": "2020-10-28",
      "has_results": false,
      "last_update_posted_date": "2020-11-13",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 2,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02506049"
    },
    {
      "nct_id": "NCT03449823",
      "title": "Renal Artery Dopplers in Twin Twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Doppler ultrasound of fetal renal artery",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 24,
      "start_date": "2016-09-09",
      "completion_date": "2018-06-30",
      "has_results": false,
      "last_update_posted_date": "2018-07-18",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03449823"
    },
    {
      "nct_id": "NCT00345852",
      "title": "Fetoscopic Selective Laser Photocoagulation in Twin-Twin Transfusion Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin to Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Fetoscopic Selective Laser Photocoagulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 150,
      "start_date": "2002-03",
      "completion_date": "2007-05",
      "has_results": false,
      "last_update_posted_date": "2007-06-29",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 12,
      "location_summary": "San Francisco, California • Evanston, Illinois • New York, New York + 7 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00345852"
    },
    {
      "nct_id": "NCT02122328",
      "title": "Sequential vs. Standard Laser Treatment of Twin-twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Sequential laser photocoagulation of communicating vessels.",
          "type": "PROCEDURE"
        },
        {
          "name": "Selective laser photocoagulation of communicating vessels",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 55 Years · Female only"
      },
      "enrollment_count": 642,
      "start_date": "2010-06-09",
      "completion_date": "2023-10-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02122328"
    },
    {
      "nct_id": "NCT06084247",
      "title": "The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin to Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Curved KARL STORZ fetoscope",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Scopes",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jimmy Espinoza",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 160,
      "start_date": "2025-09-01",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-05-22T07:49:23.738Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06084247"
    }
  ]
}