{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ulcer%2C+Leg",
    "query": {
      "condition": "Ulcer, Leg"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 546,
    "total_pages": 55,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ulcer%2C+Leg&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-21T20:05:57.765Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05579743",
      "title": "Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot",
        "Diabetic Foot Ulcer",
        "Wound; Foot",
        "Wound Leg",
        "Wound Heal",
        "Diabetes Complications"
      ],
      "interventions": [
        {
          "name": "Remote wound monitoring technology",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 148,
      "start_date": "2022-07-01",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2026-07-02",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05579743"
    },
    {
      "nct_id": "NCT04647240",
      "title": "MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Venous Stasis Ulcer",
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "MTX-001 (human amniotic fluid)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Merakris Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2022-02-26",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 11,
      "location_summary": "Tucson, Arizona • Castro Valley, California • Fresno, California + 7 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04647240"
    },
    {
      "nct_id": "NCT03135535",
      "title": "Micro-mobile Foot Compression and Diabetic Foot",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes",
        "PAD",
        "Lower Extremity Edema",
        "Neuropathy;Peripheral",
        "Foot Ulcer, Diabetic",
        "Lymphatic Diseases"
      ],
      "interventions": [
        {
          "name": "Avex Footbeat",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-05-02",
      "completion_date": "2021-05-14",
      "has_results": true,
      "last_update_posted_date": "2021-10-28",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03135535"
    },
    {
      "nct_id": "NCT05506215",
      "title": "Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot",
        "Chronic Foot Ulcer",
        "Wound Healing",
        "Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "SynPath Acellular Dermal Matrix plus Off-loading Device",
          "type": "DEVICE"
        },
        {
          "name": "Wound Dressing composed of 90% collagen and 10% Alginate plus Off-loading Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "PolyNovo Biomaterials Pty Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2022-07-10",
      "completion_date": "2024-02-26",
      "has_results": false,
      "last_update_posted_date": "2024-03-05",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 7,
      "location_summary": "Castro Valley, California • Fresno, California • Vista, California + 4 more",
      "locations": [
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Vista",
          "state": "California"
        },
        {
          "city": "Tamarac",
          "state": "Florida"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05506215"
    },
    {
      "nct_id": "NCT06702852",
      "title": "Effect of NIRS-assisted Assessment on Chronic Lower Extremity and Other Chronic Non-healing Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ulcers"
      ],
      "interventions": [
        {
          "name": "NIRS imaging in addition to SOC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kent Imaging Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 221,
      "start_date": "2024-07-22",
      "completion_date": "2025-02-25",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 4,
      "location_summary": "New Braunfels, Texas • San Antonio, Texas • San Marcos, Texas",
      "locations": [
        {
          "city": "New Braunfels",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "San Marcos",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06702852"
    },
    {
      "nct_id": "NCT04901013",
      "title": "Clinical Study Of Affinity Versus SOC In The Management Of VLUs",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Affinity",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Organogenesis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-06-14",
      "completion_date": "2023-06",
      "has_results": false,
      "last_update_posted_date": "2021-09-08",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 1,
      "location_summary": "Carlsbad, California",
      "locations": [
        {
          "city": "Carlsbad",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04901013"
    },
    {
      "nct_id": "NCT05311124",
      "title": "Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound Care",
        "Pressure Ulcer",
        "Venous Ulcer",
        "Surgical Wound",
        "Trauma Wounds",
        "Draining Wound"
      ],
      "interventions": [
        {
          "name": "Integra Dermal Regeneration template (IDRT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Joshua Choo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "55 Years to 100 Years"
      },
      "enrollment_count": 10,
      "start_date": "2022-08-01",
      "completion_date": "2023-10-01",
      "has_results": false,
      "last_update_posted_date": "2022-10-18",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05311124"
    },
    {
      "nct_id": "NCT02461641",
      "title": "NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foot Ulcer, Diabetic"
      ],
      "interventions": [
        {
          "name": "NuShield",
          "type": "OTHER"
        },
        {
          "name": "Affinity",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NuTech Medical, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2015-03",
      "completion_date": "2018-10-25",
      "has_results": false,
      "last_update_posted_date": "2019-02-22",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 7,
      "location_summary": "Fresno, California • Indianapolis, Indiana • Opelousas, Louisiana + 4 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Opelousas",
          "state": "Louisiana"
        },
        {
          "city": "Dunmore",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02461641"
    },
    {
      "nct_id": "NCT03820947",
      "title": "VenaSeal Spectrum: Global Post-Market Randomized Controlled Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Reflux"
      ],
      "interventions": [
        {
          "name": "VenaSeal™ System",
          "type": "DEVICE"
        },
        {
          "name": "Endothermal Ablation (ETA)",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Stripping",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Medtronic Endovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 506,
      "start_date": "2020-02-05",
      "completion_date": "2025-11-10",
      "has_results": true,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 12,
      "location_summary": "Prescott Valley, Arizona • Tucson, Arizona • Fresno, California + 9 more",
      "locations": [
        {
          "city": "Prescott Valley",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03820947"
    },
    {
      "nct_id": "NCT05687656",
      "title": "Sterilised, Porcine Placental Tissue in the Treatment of Chronic Diabetic Foot Ulcers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "InnovaMatrix AC porcine placental ECM therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ConvaTec Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2022-10-06",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-07-21T20:05:57.765Z",
      "location_count": 5,
      "location_summary": "North Port, Florida • Buffalo, New York • Monroeville, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "North Port",
          "state": "Florida"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Monroeville",
          "state": "Pennsylvania"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Stafford",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05687656"
    }
  ]
}