{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Upper+GI+Symptoms",
    "query": {
      "condition": "Upper GI Symptoms"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 30,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Upper+GI+Symptoms&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T05:32:56.351Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03458000",
      "title": "Capsule Endoscopy for HEmorrhage in the ER",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Upper Gastrointestinal Bleeding"
      ],
      "interventions": [
        {
          "name": "PillCam UGI",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2018-04-17",
      "completion_date": "2020-09-07",
      "has_results": true,
      "last_update_posted_date": "2023-06-01",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Durham, North Carolina • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03458000"
    },
    {
      "nct_id": "NCT00390182",
      "title": "Low Dose Upper Abdominal Radiation Therapy (LD-UART) + Gemcitabine in Patients With Advanced, Unresectable Pancreatic Cancer (PC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Gastrointestinal Neoplasms",
        "Ovarian Neoplasms"
      ],
      "interventions": [
        {
          "name": "Gemcitabine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2003-10",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2020-03-18",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00390182"
    },
    {
      "nct_id": "NCT05746377",
      "title": "Metoclopramide in Upper Gastrointestinal Bleed",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Upper GI Bleeding",
        "Bleeds Gastric",
        "Bleed Ulcer",
        "Hemorrhage Gastric",
        "Hemorrhage; Ulcer"
      ],
      "interventions": [
        {
          "name": "Metoclopramide 10mg",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mercy Health System",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-05-20",
      "completion_date": "2024-06",
      "has_results": false,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 1,
      "location_summary": "Rockford, Illinois",
      "locations": [
        {
          "city": "Rockford",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05746377"
    },
    {
      "nct_id": "NCT00241527",
      "title": "Esomeprazole for Relief of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "NSAIDs",
        "Upper GI Symptoms"
      ],
      "interventions": [
        {
          "name": "Esomeprazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AstraZeneca",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 556,
      "start_date": "2000-12",
      "completion_date": "2002-09",
      "has_results": false,
      "last_update_posted_date": "2011-01-24",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 32,
      "location_summary": "Tallassee, Alabama • Phoenix, Arizona • Garden Grove, California + 29 more",
      "locations": [
        {
          "city": "Tallassee",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00241527"
    },
    {
      "nct_id": "NCT03065465",
      "title": "Standard Endoscopic Hemostasis Versus OVESCO Severe Non-variceal UGI Hemorrhage",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Upper Gastrointestinal Hemorrhage"
      ],
      "interventions": [
        {
          "name": "Over-the-scope hemoclipping device",
          "type": "DEVICE"
        },
        {
          "name": "Standard endoscopic treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "CURE Digestive Diseases Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 65,
      "start_date": "2015-11-15",
      "completion_date": "2025-02-28",
      "has_results": false,
      "last_update_posted_date": "2024-08-27",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03065465"
    },
    {
      "nct_id": "NCT00241553",
      "title": "Esomeprazole for Prevention of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "NSAIDs",
        "Upper GI Symptoms"
      ],
      "interventions": [
        {
          "name": "Esomeprazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AstraZeneca",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 276,
      "start_date": "2001-04",
      "completion_date": "2003-02",
      "has_results": false,
      "last_update_posted_date": "2011-01-24",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 31,
      "location_summary": "Tallassee, Alabama • Phoenix, Arizona • Garden Grove, California + 28 more",
      "locations": [
        {
          "city": "Tallassee",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00241553"
    },
    {
      "nct_id": "NCT00579410",
      "title": "Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Esophagitis",
        "Inflammation",
        "Gastritis",
        "Abdominal Pain",
        "Heartburn"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2004-05",
      "completion_date": "2009-10",
      "has_results": false,
      "last_update_posted_date": "2011-03-22",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00579410"
    },
    {
      "nct_id": "NCT00475592",
      "title": "Validation of Esophageal Variceal Grading: A Comparative Study of Upper Gastrointestinal (GI) Endoscopy and Capsule Endoscopy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Esophageal and Gastric Varices"
      ],
      "interventions": [
        {
          "name": "Esophageal Capsule Endoscopy",
          "type": "DEVICE"
        },
        {
          "name": "Upper Gastrointestinal Endoscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2007-01",
      "completion_date": "2008-05",
      "has_results": false,
      "last_update_posted_date": "2017-07-24",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475592"
    },
    {
      "nct_id": "NCT03642093",
      "title": "HOPE - A Study to Evaluate the Effect of a Prehabilitation Program on GI Cancer Patients Planning to Undergo Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pancreatic Cancer",
        "Esophageal Cancer",
        "Gastric Cancer"
      ],
      "interventions": [
        {
          "name": "Nutritional Intervention",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Physical Activity Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "BEHAVIORAL"
      ],
      "sponsor": "Siobhan Trotter",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "25 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-08-01",
      "completion_date": "2019-05",
      "has_results": false,
      "last_update_posted_date": "2018-09-11",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03642093"
    },
    {
      "nct_id": "NCT03090945",
      "title": "Pediatric Acute Gastrointestinal Bleeding Registry",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Upper Gastrointestinal Bleeding",
        "Gastro Intestinal Bleeding"
      ],
      "interventions": [
        {
          "name": "This is an obsevational cohort study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 300,
      "start_date": "2017-05-01",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2020-09-16",
      "last_synced_at": "2026-07-23T05:32:56.351Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Houston, Texas",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03090945"
    }
  ]
}