{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Upper+Respiratory+Disease",
    "query": {
      "condition": "Upper Respiratory Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 223,
    "total_pages": 23,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Upper+Respiratory+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:48:49.167Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00228254",
      "title": "Vitamin A and Zinc: Prevention of Pneumonia (VAZPOP) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pneumonia",
        "Diarrhea",
        "Acute Upper Respiratory Tract Infections"
      ],
      "interventions": [
        {
          "name": "Zinc (12.5 mg/day)",
          "type": "DRUG"
        },
        {
          "name": "vitamin A 10,000 IU per week",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "6 Months to 36 Months"
      },
      "enrollment_count": 2582,
      "start_date": "2000-01",
      "completion_date": "2004-06",
      "has_results": false,
      "last_update_posted_date": "2005-09-28",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00228254"
    },
    {
      "nct_id": "NCT06101199",
      "title": "Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Acute Intermittent Hypercapnic Hypoxia",
          "type": "OTHER"
        },
        {
          "name": "Transcutaneous spinal cord stimulation",
          "type": "OTHER"
        },
        {
          "name": "SHAM Acute Intermittent Hypercapnic Hypoxia",
          "type": "OTHER"
        },
        {
          "name": "SHAM Transcutaneous spinal cord stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 4,
      "start_date": "2023-10-16",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-17",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06101199"
    },
    {
      "nct_id": "NCT04139499",
      "title": "Use of High-resolution Manometry to Detect Upper Airway Obstruction During Sleep",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Drug-induced sleep endoscopy (DISE)",
          "type": "PROCEDURE"
        },
        {
          "name": "High-resolution manometry (HRM):",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "5 Years to 90 Years"
      },
      "enrollment_count": 18,
      "start_date": "2019-01-16",
      "completion_date": "2021-05-05",
      "has_results": false,
      "last_update_posted_date": "2025-11-13",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04139499"
    },
    {
      "nct_id": "NCT05292677",
      "title": "Laryngeal Nerve Block for Chronic Cough",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Laryngeal Nerve Block",
        "Chronic Neurogenic Cough",
        "Laryngeal Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Steroid/Anesthesia Mixture",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eastern Virginia Medical School",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2021-07-21",
      "completion_date": "2023-06-25",
      "has_results": false,
      "last_update_posted_date": "2022-03-23",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05292677"
    },
    {
      "nct_id": "NCT04505098",
      "title": "A Pragmatic Randomized Trial of Icosapent Ethyl for High-Cardiovascular Risk Adults",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Covid19",
        "Atherosclerosis",
        "Cardiovascular Diseases",
        "Upper Respiratory Tract Infections"
      ],
      "interventions": [
        {
          "name": "Icosapent ethyl",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 39600,
      "start_date": "2020-08-07",
      "completion_date": "2022-12-15",
      "has_results": false,
      "last_update_posted_date": "2023-07-18",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Oakland, California",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04505098"
    },
    {
      "nct_id": "NCT01939938",
      "title": "Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea (OSA)"
      ],
      "interventions": [
        {
          "name": "Nasal and Oronasal PAP Mask",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2013-06",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2018-07-17",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01939938"
    },
    {
      "nct_id": "NCT01744145",
      "title": "Effect of Exercise and Education After Pneumonia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pneumonia"
      ],
      "interventions": [
        {
          "name": "Interventional 40-60",
          "type": "OTHER"
        },
        {
          "name": "Interventional 60 and above",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Winthrop University Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2012-08",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Mineola, New York",
      "locations": [
        {
          "city": "Mineola",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01744145"
    },
    {
      "nct_id": "NCT00001936",
      "title": "Electrical Muscle Stimulation to Aid Swallowing in Dysphagia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Deglutition Disorder",
        "Healthy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "Up to 90 Years"
      },
      "enrollment_count": 155,
      "start_date": "1999-09-28",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001936"
    },
    {
      "nct_id": "NCT04826809",
      "title": "New Reusable Mask Design With Superior Filtration and Fit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Covid19",
        "Tuberculosis",
        "Respiratory Viral Infection"
      ],
      "interventions": [
        {
          "name": "N95 mask",
          "type": "DEVICE"
        },
        {
          "name": "Nordell single E-100 layer mask",
          "type": "DEVICE"
        },
        {
          "name": "Nordell double E-100 layer mask",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2021-04-09",
      "completion_date": "2022-10-27",
      "has_results": true,
      "last_update_posted_date": "2023-07-07",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Mankato, Minnesota",
      "locations": [
        {
          "city": "Mankato",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04826809"
    },
    {
      "nct_id": "NCT03388645",
      "title": "Challenge Infection of Healthy Adult Volunteers With RSV A2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Upper Respiratory Tract Infections"
      ],
      "interventions": [
        {
          "name": "10^6.3 PFU of RSV A2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "10^7 PFU of RSV A2",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 19,
      "start_date": "2018-02-20",
      "completion_date": "2019-12-06",
      "has_results": true,
      "last_update_posted_date": "2020-12-03",
      "last_synced_at": "2026-05-22T07:48:49.167Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03388645"
    }
  ]
}