{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vaginal+Dysbiosis",
    "query": {
      "condition": "Vaginal Dysbiosis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T06:14:55.099Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04118049",
      "title": "Vaginal Probiotics and Pessaries and Their Impact on the Vaginal Microenvironment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Organ Prolapse",
        "Inflammatory Response",
        "Dysbiosis"
      ],
      "interventions": [
        {
          "name": "BiopHreshTM vaginal probiotic supplement (Good Clean Love, Inc. Eugene, OR) and RestoreTM gel.",
          "type": "OTHER"
        },
        {
          "name": "Standard Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Hartford Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 89 Years · Female only"
      },
      "enrollment_count": 141,
      "start_date": "2019-10-30",
      "completion_date": "2021-05-30",
      "has_results": false,
      "last_update_posted_date": "2022-03-25",
      "last_synced_at": "2026-06-11T06:14:55.099Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04118049"
    },
    {
      "nct_id": "NCT07526948",
      "title": "Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Menopausal Complaints",
        "Vaginal Atrophy",
        "Genitourinary Symptoms",
        "HIV (Human Immunodeficiency Virus)",
        "Menopause Related Conditions",
        "Vaginitis",
        "Perimenopause"
      ],
      "interventions": [
        {
          "name": "Vaginal estradiol tablets",
          "type": "DRUG"
        },
        {
          "name": "Vaginal moisturizer",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 70 Years · Female only"
      },
      "enrollment_count": 62,
      "start_date": "2026-06-01",
      "completion_date": "2031-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-06-11T06:14:55.099Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07526948"
    },
    {
      "nct_id": "NCT06470906",
      "title": "Feasibility of an Oral Intervention for Sexual Health in Transgender Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vaginal Dysbiosis",
        "Vaginal Disease",
        "Molecular-bacterial Vaginosis"
      ],
      "interventions": [
        {
          "name": "Probiotic Group",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Group",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 29,
      "start_date": "2024-08-14",
      "completion_date": "2024-11-21",
      "has_results": false,
      "last_update_posted_date": "2025-05-09",
      "last_synced_at": "2026-06-11T06:14:55.099Z",
      "location_count": 1,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06470906"
    },
    {
      "nct_id": "NCT07453069",
      "title": "Effect of FB301 on Vaginal Bacterial Profile in Women With Asymptomatic Vaginal Dysbiosis Undergoing a Mock Frozen Embryo Transfer Cycle",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vaginal Dysbiosis"
      ],
      "interventions": [
        {
          "name": "FB-301",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Chlorhexidine (0.5%) Vaginal Cleanse",
          "type": "OTHER"
        },
        {
          "name": "Sham vaginal cleanse (saline)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Freya Biosciences ApS",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2026-04-15",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-06-11T06:14:55.099Z",
      "location_count": 1,
      "location_summary": "Waltham, Massachusetts",
      "locations": [
        {
          "city": "Waltham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07453069"
    },
    {
      "nct_id": "NCT04079218",
      "title": "Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "HIV Infection",
        "Vaginal Atrophy",
        "Menopause",
        "Menopause Related Conditions",
        "Aging",
        "Premature Aging",
        "Atrophic Vaginitis",
        "Dysbiosis",
        "Vaginitis"
      ],
      "interventions": [
        {
          "name": "Estradiol Vaginal Insert",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kerry Murphy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 70 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2020-09-01",
      "completion_date": "2023-08-09",
      "has_results": true,
      "last_update_posted_date": "2025-03-14",
      "last_synced_at": "2026-06-11T06:14:55.099Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04079218"
    }
  ]
}