{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vascular+Cognitive+Impairment&page=4",
    "query": {
      "condition": "Vascular Cognitive Impairment",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 144,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vascular+Cognitive+Impairment&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vascular+Cognitive+Impairment&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T08:30:59.744Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04637100",
      "title": "Gaming Apps Post-Stroke",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Cognitive Impairment",
        "Executive Dysfunction",
        "Cognitive Change",
        "Cognitive Deficit"
      ],
      "interventions": [
        {
          "name": "Mobile or tablet-based gaming applications",
          "type": "OTHER"
        },
        {
          "name": "Stroke-related educational videos",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-12",
      "completion_date": "2022-04",
      "has_results": false,
      "last_update_posted_date": "2021-06-16",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04637100"
    },
    {
      "nct_id": "NCT07416734",
      "title": "RCT of HeartBot in Women",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Participants Must be Women Aged 25 Years or Older",
        "Participants Should Have no Self-reported History of Heart Disease or Stroke",
        "Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease",
        "Participants Should Not be a Healthcare Professionals or Healthcare Trainees",
        "Participants Should Not be Employed in the Healthcare Field",
        "Participants Should Reside in the United States and be a University of California, San Francisco Health Patient",
        "Participants Should Possess a Smartphone With an Active Data Plan or Access to Wi-Fi"
      ],
      "interventions": [
        {
          "name": "HeartBot II Program",
          "type": "OTHER"
        },
        {
          "name": "Waitlist Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "25 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2026-03-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07416734"
    },
    {
      "nct_id": "NCT00227994",
      "title": "Acetylcholinesterase Inhibitors to Improve Cognitive Function and Overall Rehabilitation After a Stroke",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cerebrovascular Accident"
      ],
      "interventions": [
        {
          "name": "Galantamine",
          "type": "DRUG"
        },
        {
          "name": "Donepezil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2003-04",
      "completion_date": "2005-03",
      "has_results": true,
      "last_update_posted_date": "2017-12-11",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00227994"
    },
    {
      "nct_id": "NCT01140854",
      "title": "Cognitive Dysfunction in Hypertensive Patients Having Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Lumbar spine surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Neurologic/neuropsychometric examinations",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "60 Years to 90 Years"
      },
      "enrollment_count": 179,
      "start_date": "2009-01",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2015-06-04",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01140854"
    },
    {
      "nct_id": "NCT00605072",
      "title": "The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cognitive Impairment",
        "Hypertension",
        "Aging"
      ],
      "interventions": [
        {
          "name": "candesartan",
          "type": "DRUG"
        },
        {
          "name": "lisinopril",
          "type": "DRUG"
        },
        {
          "name": "hydrochlorothiazide",
          "type": "DRUG"
        },
        {
          "name": "nifedipine, long acting",
          "type": "DRUG"
        },
        {
          "name": "metoprolol, long-acting",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2008-01",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2013-02-15",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Boston, Massachusetts",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00605072"
    },
    {
      "nct_id": "NCT01953705",
      "title": "n-3 PUFA for Vascular Cognitive Aging",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Age Related Cognitive Decline",
        "Alzheimer's Disease",
        "Vascular Dementia",
        "Endothelial Dysfunction",
        "Executive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Omega 3 PUFA",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "75 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "75 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2014-05",
      "completion_date": "2021-06",
      "has_results": false,
      "last_update_posted_date": "2020-09-04",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01953705"
    },
    {
      "nct_id": "NCT02777060",
      "title": "Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Cancer",
        "Multiple Sclerosis",
        "Arthritis",
        "Parkinson's Disease",
        "Cognitive Disorders",
        "Brain Injury",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Exergame",
          "type": "PROCEDURE"
        },
        {
          "name": "Home based balance training",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2014-09",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2016-05-19",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02777060"
    },
    {
      "nct_id": "NCT02080520",
      "title": "Nattokinase Atherothrombotic Prevention Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prevention of Subclinical Atherosclerosis Progression",
        "Prevention of Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Nattokinase",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "55 Years to 100 Years"
      },
      "enrollment_count": 265,
      "start_date": "2014-04",
      "completion_date": "2019-07-31",
      "has_results": true,
      "last_update_posted_date": "2024-03-19",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02080520"
    },
    {
      "nct_id": "NCT05741060",
      "title": "Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Arterial Stiffness",
        "White Matter Lesions",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "S-equol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Akira Sekikawa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 369,
      "start_date": "2023-06-29",
      "completion_date": "2027-01-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Winston-Salem, North Carolina • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05741060"
    },
    {
      "nct_id": "NCT03885674",
      "title": "Improving Medication Self-Administration and Health After Brain Injury",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Stroke, Acute",
        "Cognitive Impairment",
        "Brain Injuries, Traumatic",
        "Medication Adherence",
        "Medication Compliance"
      ],
      "interventions": [
        {
          "name": "Video Call Reminder Condition",
          "type": "OTHER"
        },
        {
          "name": "Automated Text Message Reminder Condition",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2016-07",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-02-17",
      "last_synced_at": "2026-10-09T08:30:59.744Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03885674"
    }
  ]
}